A5057956522- Ocular Oncology and Treatments
- Urticaria and Related Conditions
- Vasculitis and related conditions
- Glaucoma and retinal disorders
- Ocular Infections and Treatments
- Ocular Diseases and Behçet’s Syndrome
- Cancer and Skin Lesions
- Nonmelanoma Skin Cancer Studies
- Histiocytic Disorders and Treatments
- Sarcoidosis and Beryllium Toxicity Research
- Autoimmune and Inflammatory Disorders
- Cutaneous Melanoma Detection and Management
- Vascular Malformations and Hemangiomas
- Nail Diseases and Treatments
- Ear and Head Tumors
- Corneal surgery and disorders
- Hereditary Neurological Disorders
- Effects of Radiation Exposure
- Pregnancy and preeclampsia studies
- Medical Imaging and Pathology Studies
- Genetic and rare skin diseases.
- Retinal and Optic Conditions
- Myofascial pain diagnosis and treatment
- Lung Cancer Treatments and Mutations
- Retinopathy of Prematurity Studies
Douglass Hanly Moir Pathology
2016-2024
Macquarie University
2018-2024
Westmead Hospital
2015
The University of Sydney
2006
In this study, differentiation of pterygium vs. ocular surface squamous neoplasia based on multispectral autofluorescence imaging technique was investigated. Fifty (N = 50) patients with histopathological diagnosis (PTG) and/or (OSSN) were recruited. Fixed unstained biopsy specimens imaged by microscopy. Tissue images obtained a custom-built fluorescent microscope 59 spectral channels, each specific excitation and emission wavelength ranges, suitable for the most abundant tissue fluorophores...
Clinical OSSN diagnostics by non-invasive spectral imaging of eye autofluorescence must be rapid enough to comfortable for patients - without compromising accuracy. This requires identifying optimized signatures based on a minimal number spectrally defined images. Here, we identified such using data-driven methodology swarm intelligence. Ten with histopathological diagnosis ocular surface squamous neoplasia (OSSN) were recruited. Their unstained biopsy specimens investigated custom-built...
In recent years, an immune-mediated disorder involving IgG4 has been described, which targets multiple organs and explains a number of disorders previously regarded as "idiopathic" or unknown origin. Furthermore, the discovery IgG4-related disease (IgG4-RD) placed pathologies within its spectrum, linking symptoms conditions formerly considered isolated. Reports manifestations IgG4-RD in head neck are scarce. Otological have reported, but only handful cases available literature. This is first...
<b>Background:</b> Differentiation patterns of the neural retina and its retinal vasculature are not well matched. The foveal region differentiates first, however central is vascularised until late in gestation. authors explored hypothesis that higher rates endothelial cell proliferation choriocapillaris might compensate for slow growth vessels, providing supplementary nutrients to during early stages neuronal maturation. <b>Methods:</b> Frozen sections five human fetal eyes (14–18.5 weeks’...
Purpose: The purpose of this study was to provide Australian data on the clinical and radiological features outcomes in patients with orbital plasmacytomas. Methods: Multicentre retrospective review plasmacytoma involvement multiple myeloma (MM) from 2005 2022 Australia. Results: Twenty-one participants were identified. median age 62 years (range 34–88 years), 11 (52%) females. Eighteen (84%) had a known diagnosis MM prior their presentation, all eventually being diagnosed systemic MM....
Psoriasis vulgaris is a chronic benign disease of the whole thickness epidermis with symptomatic plaque formation impacting quality life. Relatively low doses fractionated radiotherapy (RT) have been used in past to total dose four six Gray (Gy). We present case an older male seven recalcitrant plaques each treated same prescribed RT. Superficial (SXRT) 100kV beam from Xstrahl 300 machine 20 Gy 10 fractions (#s) at five #s per week was for areas - on scalp and one elbow. At months post...
Introduction: In this study, we investigated the presence of motilin receptors (MR) in adnexal tissue including human main lacrimal gland.Method: 17 specimens comprising 11 isolated gland specimens, four full-thickness eyelid excisions and two exenterations containing portions were immunolabelled with a rabbit polyclonal MR antibody.Results: Our results demonstrated that all (13/13, 100%) positive for expression predominance (10/13 (77%) grade 1+ punctate distribution. Motilin not found...
A man in his 60s presented to the emergency department with marked bilateral preauricular swelling, associated jaw claudication, temporal tenderness and blurred vision. He was immediately treated for arteritis by commencing systemic corticosteroids. artery biopsy showed no evidence of vasculitis. However, positron emission tomography-CT demonstrated increased uptake medium-large vessels, including left superficial aorta. This case illustrates that facial swelling may be an under-recognised...