A5013932260- Biosensors and Analytical Detection
- Amino Acid Enzymes and Metabolism
- Tracheal and airway disorders
- Adenosine and Purinergic Signaling
- RNA modifications and cancer
- Gastric Cancer Management and Outcomes
- Diabetes Treatment and Management
- Genetic factors in colorectal cancer
- TGF-β signaling in diseases
- Antiplatelet Therapy and Cardiovascular Diseases
- Blood Coagulation and Thrombosis Mechanisms
- Glycosylation and Glycoproteins Research
- Advanced biosensing and bioanalysis techniques
- Lung Cancer Research Studies
- Berberine and alkaloids research
- Protease and Inhibitor Mechanisms
- Analytical Chemistry and Sensors
- S100 Proteins and Annexins
- Lung Cancer Diagnosis and Treatment
- Cancer Genomics and Diagnostics
- Cancer Immunotherapy and Biomarkers
- Mycobacterium research and diagnosis
- Ubiquitin and proteasome pathways
- Ginger and Zingiberaceae research
Fujian Medical University
2021-2025
Endothelial cell dysfunction plays a crucial role in the early development of cerebral small vessel disease (CSVD). Arginase-1 (ARG1) is expressed endothelial cells, and its deficiency may exacerbate cerebrovascular damage by increasing reactive oxygen species (ROS) production, thereby inducing apoptosis. Berbamine (BBM) has shown potential neuroprotection cardiovascular prevention. This study aimed to investigate impact ARG1 on human brain microvascular cells protective effects BBM against...
The objective of this study was to investigate the relationship between P2Y1 and P2Y12 genotypes risk acute myocardial infarction (AMI) in Quanzhou population determine associations ADP-induced platelet aggregation population.All subjects were screened for (c.1622A > G) (H1/H2, c.34C T) polymorphisms by direct DNA sequencing. maximal rate (MAR) AMI patients (n = 61) healthy control 50) measured a PL-12 function analyzer, adenosine diphosphate (ADP) (5 μmol/L) used as an agonist.The haploid...
To explore the predictive value of plasma cell-free DNA (cf-DNA) for prognosis in patients with sepsis.105 sepsis admitted to department emergency First Hospital Quanzhou Affiliated Fujian Medical University from June 2015 2017 were enrolled. Patients divided into group (n = 50) and severe 55). At same time, 50 cases physical examination center our hospital randomly selected as healthy control group. The differences cf-DNA, procalcitonin (PCT) acute physiology chronic health evaluation II...
This study aimed to evaluate the prognostic value and biological function of small ubiquitin‐like modifier 2 ( SUMO2 ) in hepatocellular carcinoma (HCC). expression HCC tissues was markedly higher than that normal liver tissues, patients with high had significantly shorter median overall survival those low expression. Furthermore, closely correlated lymph node metastasis vascular invasion a predictor poor prognosis. The knockdown two cell lines (SMMC‐7721 Bel‐7404) dramatically suppressed...
Potentiometric immunoassays have been utilized for the quantitative detection of alpha-fetoprotein (AFP) in hepatocellular carcinoma, but most them involve low sensitivity and enzyme labels, thus are unfavorable routine use. In this work, we report proof-of-concept a sensitive powerful ion-selective potentiometric sensing method AFP with an situ amplified signal readout. This immunoassay mainly contains silver nanocluster-functionalized single-stranded DNA (AgNC-DNA), short primer two...
To determine the plasminogen activator inhibitor-1 (PAI-1) 4G/5G (rs1799889) genotype of subjects in a robust detection method and to explore association PAI-1 polymorphism with susceptibility diabetes mellitus (DM) hypertension (HTN) as well clinical characteristics.This study recruited 208 patients (68 were diagnosed DM, 70 HTN DM combined HTN) 132 healthy controls (HC). A subset population was selected evaluate accuracy Real-time PCR (RT-PCR) for detecting by using sequencing gold...