Zixuan Chen

ORCID: 0000-0002-3017-1121
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About
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Research Areas
  • Advanced biosensing and bioanalysis techniques
  • Electrochemical Analysis and Applications
  • Electrochemical sensors and biosensors
  • Asphalt Pavement Performance Evaluation
  • Infrastructure Maintenance and Monitoring
  • Microbial Fuel Cells and Bioremediation
  • Perovskite Materials and Applications
  • Biosensors and Analytical Detection
  • Nanoplatforms for cancer theranostics
  • Gold and Silver Nanoparticles Synthesis and Applications
  • Conducting polymers and applications
  • Geotechnical Engineering and Underground Structures
  • Molecular Junctions and Nanostructures
  • Advanced Nanomaterials in Catalysis
  • Supercapacitor Materials and Fabrication
  • Ubiquitin and proteasome pathways
  • Hemoglobinopathies and Related Disorders
  • RNA Interference and Gene Delivery
  • Multiferroics and related materials
  • Nanopore and Nanochannel Transport Studies
  • Electrocatalysts for Energy Conversion
  • Quantum Dots Synthesis And Properties
  • Advancements in Battery Materials
  • Luminescence and Fluorescent Materials
  • Geology and Paleoclimatology Research

Nanjing University
2015-2025

State Key Laboratory of Pollution Control and Resource Reuse
2024-2025

Southeast University
2022-2025

Chang'an University
2022-2025

Huazhong University of Science and Technology
2025

Nanjing Institute of Agricultural Mechanization
2024

Ministry of Agriculture and Rural Affairs
2024

Fujian Medical University
2015-2024

Wuhan Textile University
2024

Hebei Agricultural University
2024

Abstract A bio‐coreactant‐enhanced electrochemiluminescence (ECL) microscopy realizes the ECL imaging of intracellular structure and dynamic transport. This uses Ru(bpy) 3 2+ as electrochemical molecular antenna connecting extracellular environments, biomolecules coreactants reactions via a “catalytic route”. Accordingly, structures are identified without using multiple labels, autophagy involving DNA oxidative damage is detected nuclear signals. time‐resolved image sequence discloses...

10.1002/anie.202012171 article EN Angewandte Chemie International Edition 2020-11-14

This article describes a multimodified core–shell gold@silver nanoprobe for real-time monitoring the entire autophagy process at single-cell level. Autophagy is vital understanding mechanisms of human pathologies, developing novel drugs, and exploring approaches controlling. A major challenge study lies in monitoring. One solution might come from detection situ superoxide radicals (O2•–), because it main regulator autophagy. In this work, our proposed nanoprobes were etched by O2•– gave...

10.1021/ja5112628 article EN Journal of the American Chemical Society 2015-01-21

The quest for new techniques to measure single nanomaterials is a great impetus research efforts understand individual behaviours. Here, we develop an electrochemiluminescence (ECL) microscopy visualization of stochastic collision electrochemistry nano-emitters without the interference current and optical background. This design uses water-immersion objective capture ECL emission nanoparticles near specular electrode surface enhancing light collection efficiency. approach enables us trace...

10.1039/c8sc02251h article EN cc-by-nc Chemical Science 2018-01-01

Single-cell imaging is essential for elucidating the biological mechanism of cell function because it accurately reveals heterogeneity among cells. The electrochemiluminescence (ECL) microscopy technique has been considered a powerful tool to study cells its high throughput and zero cellular background light. However, since are immobilized on electrode surface, steric hindrance insulation from make difficult obtain luminous ECL image. To solve this problem, direct single was investigated...

10.1021/acs.analchem.8b00194 article EN Analytical Chemistry 2018-03-06

Monitoring and characterization methods that provide performance tracking of hydrogen evolution reaction (HER) at the single-nanoparticle level can greatly advance our understanding catalysts' structure activity relationships. Electrochemiluminescence (ECL) microscopy is implemented for first time to identify HER activities single nanocatalysts a direction further optimization. Here, we develop novel ECL blinking technique directly monitor H2 nanobubbles generated from hollow carbon nitride...

10.1021/acs.nanolett.0c01129 article EN Nano Letters 2020-06-09

C-C coupling is of utmost importance in the electrocatalytic reduction CO

10.1038/s41467-024-51397-4 article EN cc-by-nc-nd Nature Communications 2024-08-20

Double perovskites Cs2AgSbCl6 have been synthesized via the solution state for applications as a promising photovoltaic absorber. Considering TiO2 an electron transport layer (ETL), Cs2AgSbCl6/TiO2 heterojunction nanoparticles also prepared by hydrothermal process to study interface effect. Experimental measurements show that has cubic structure with lattice constant of 10.699 Å. The absorption peaks in optical spectrum Ag and Sb-based double agree well our density functional theory...

10.1063/1.4999192 article EN Applied Physics Letters 2017-10-09

Measuring local heat generation and dissipation in nanomaterials is critical for understanding the basic properties developing applications of nanomaterials, including photothermal therapy joule heating nanoelectronics. Several technologies have been developed to probe temperature distributions but a sensitive thermal imaging technology with high temporal spatial resolution still lacking. Here, we describe plasmonic microscopy (PTM) image diffusion from nanostructures biologically relevant...

10.1021/acsnano.5b05306 article EN ACS Nano 2015-10-04

Abstract Lead halide perovskite quantum dots (QDs) are promising electrochemiluminescence (ECL) nanoemitters due to their fascinating photophysical properties. However, poor structural stability against the external environment, trade‐off between colloidal and carrier injection/transport efficiency is a major challenge in advancement of perovskite‐based ECL technology. In this work, intense stable from CsPbBr 3 (CPB) QDs achieved by simultaneously encapsulating CPB coreactant (CoR) into situ...

10.1002/adfm.201902533 article EN Advanced Functional Materials 2019-06-04

In this work, a potential-resolved electrochemiluminescence (ECL) method is developed and used for the apoptosis diagnosis at single-cell level. The of cells usually induces decreasing expression epidermal growth factor receptor (EGFR) promotes phosphatidylserine (PS) eversion on cell membrane. Here, Au@L012 g-C3N4 as ECL probes are functionalized with (EGF) peptide (PSBP) to recognize EGFR PS surface, respectively, showing two well-separated signals during potential scanning. Experimental...

10.1021/acs.analchem.9b01401 article EN Analytical Chemistry 2019-04-09

Circularly polarized organic light-emitting diodes (CP-OLEDs) hold great potential for naked-eye 3D displays, necessitating efficient chiral luminescent materials with an optimal CP luminescence (CPL) dissymmetry factor (

10.1039/d4mh00605d article EN Materials Horizons 2024-01-01

Catalytic route electrochemiluminescence microscopy enables us to image upper cell membranes with a vertical resolution mode by using nitrogen-doped carbon dots as nano-coreactants and labels.

10.1039/d0cc08223f article EN Chemical Communications 2021-01-01

Abstract Small molecule‐based photothermal agents (PTAs) hold promising future for therapy; however, unexpected inactivation exerts negative impacts on their application clinically. Herein, a self‐regenerating PTA strategy is proposed by integrating 2,2′‐azino‐bis(3‐ethylbenzothiazoline‐6‐sulfonic acid) radical cation (ABTS •+ ) with thermodynamic agent (TDA) 2,2′‐azobis[2‐(2‐imidazolin‐2‐yl) propane] dihydrochloride (AIPH). Under NIR laser, the effect of ABTS accelerates production alkyl...

10.1002/smtd.202400697 article EN Small Methods 2024-06-02
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