A5059717477- Erythrocyte Function and Pathophysiology
- Groundwater flow and contamination studies
- Ion channel regulation and function
- Neonatal Health and Biochemistry
- Ion Transport and Channel Regulation
- Soil and Unsaturated Flow
- Hemoglobin structure and function
- Pancreatic function and diabetes
- Hemoglobinopathies and Related Disorders
- Semiconductor materials and devices
- Transition Metal Oxide Nanomaterials
- Catalytic Processes in Materials Science
- Lipid Membrane Structure and Behavior
- ZnO doping and properties
- Advanced ceramic materials synthesis
- Gas Sensing Nanomaterials and Sensors
- Enhanced Oil Recovery Techniques
- Clay minerals and soil interactions
- Hydraulic Fracturing and Reservoir Analysis
- X-ray Spectroscopy and Fluorescence Analysis
- Advanced materials and composites
- Semiconductor Quantum Structures and Devices
- Radiation Shielding Materials Analysis
- Nanotechnology research and applications
- Electrophoretic Deposition in Materials Science
Wilmington University
2025
Lewis University
2017-2020
Impact
2014-2016
Watershed Associates
2008-2012
University of Tennessee at Knoxville
2012
Cabot Microelectronics (United States)
2007-2010
Oak Ridge National Laboratory
2003-2004
Naval Medical Center San Diego
2003
Stanford SystemX Alliance
1999
Motorola (United States)
1999
Calibration curves of the Raman spectrum nanophase TiO2 to material’s oxygen stoichiometry are presented. The thermogravimetric analysis studies used determine oxygen-titanium ratio also discussed.
A theoretical model is described for the prediction of relative permeability‐saturation ( k ‐ S ) relations in two‐phase (air‐water) and three‐phase (air‐oil‐water) porous media systems subject to arbitrary saturation paths. Integral expressions air, water, oil realtive permeabilities are presented which extend nonhysteretic permeability Parker et al. (1987) accomodate effects pore blockage by air trapped water phases phase. The parametric saturation‐pressure P fluid entrapment paper 1...
This study investigates field‐scale DNAPL dissolution kinetics using high‐resolution numerical simulations of releases and dissolved phase transport. A percolation model is employed to simulate the distribution TCE within 10 × m source zones with spatially heterogeneous aquifer properties following a release event. Distributed saturations are utilized coupled groundwater flow long‐term Grid‐scale rates computed based on published bench‐scale relationships. Effective mass transfer...
When the internal Na of human red cells is raised, both K influx and lactate production increase become more sensitive to inhibitory action ouabain. This occurs with either glucose or purine nucleoside as substrate. Fresh whole hemolysates enriched Mg will convert intermediates above triose phosphate dehydrogenase step at a rate which slowed by Intermediates beyond phosphoglycerate kinase (PGK) are metabolized very rapid not affected No metabolic effects ouabain were found in ghost-free...
A simple model is proposed to account for large increases in transporter-mediated ion flux across cell membranes that are elicited by small fractional changes of volume. The based upon the concept that, as a result excluded volume effects cytoplasm (macromolecular crowding), tendency soluble macromolecules associate with membrane proteins much more sensitive water content than expected on basis considerations mass action. postulates an transporter may exist either active dephosphorylated...
An experimental apparatus was developed to directly measure functional relationships between fluid saturations S and pressures P of three‐phase (air‐oil‐water) or two‐phase systems in unconsolidated porous media. Porous ceramic rings were chemically treated enable simultaneous measurement regulation water oil pressures. Direct measurements total liquid three phase as functions oil‐water air‐oil capillary heads, respectively, compared S‐P for monotonic drainage saturation paths test commonly...
As dog red blood cells are shrunken in vitro, their sodium permeability increases progressively. Some new features of this volume-responsive transport process described. Retardation movements occurs when chloride is replaced by the more conductive anions: nitrate or thiocyanate. Micromolar concentrations amiloride quinidine inhibit increment flux associated with a reduction cell volume. In presence large outwardly directed gradient, can progressively alkalinize medium which they suspended....
Abstract The points of zero salt effect (PZSE) surface and subsurface horizons soils ranging from an Hapludoll to a Paleudult were obtained batch titrations in CaCl 2 solutions with without prior Ca saturation NaCl following Na saturation. PZSE's Na‐saturated samples equilibrated for 1 hour generally between pH 3, while those Na‐ or Ca‐saturated unwashed days 3 4. equilibration time was attributed gradual sample decomposition accompanied by conversion soil Al‐Na‐system. Points net charge...
Dog red blood cells (RBC) are shown to regulate their volume in anisosmotic media. Extrusion of water from osmotically swollen requires external calcium and is associated with net outward sodium movement. Accumulation by shrunken not dependent uptake. Net movements influenced several variables including cell volume, pH, medium concentration, cellular concentration. Osmotic swelling increases permeability, this effect diminished at acid pH. flux either direction between facilitated when the...
Several mechanisms recently proposed for regulation of the hexose monophosphate shunt require concentration NADP to be low or that NADPH high. The present study indicates first enzyme human erythrocytes is under severe restraint even when these conditions do not exist. In containing low-activity variants this enzyme, glucose-6-phosphate dehydrogenase (D-glucose-6-phosphate:NADP(+) 1-oxidoreductase; EC 1.1.1.49), measurements rate oxidation C-1 labeled glucose show operating at a much closer...
A hysteretic model for two‐phase permeability ( k )‐saturation S )‐pressure P ) relations is outlined that accounts effects of nonwetting fluid entrapment. The can be employed in unsaturated flow computer codes to predict temporal and spatial distributions. Consideration given hysteresis ‐ caused by contact angle, irregular pore geometry, entrapment effects. An air‐water experiment conducted with a 72‐cm vertical soil column where the water table fluctuated generate scanning paths. Water...
A finite‐element model is developed for multiphase flow through soil involving three immiscible fluids: namely, air, water, and a nonaqueous phase liquid (NAPL). variational method employed the formulation corresponding to coupled differential equations governing in three‐fluid porous medium system with constant air pressure. Constitutive relationships fluid conductivities saturations as functions of pressures, which are derived companion paper by J. C. Parker et al. (this issue) may be...
${\mathrm{VO}}_{2}$ single crystals were studied in an effort to resolve the differences that are present two previous reports on Raman spectra of ${\mathrm{VO}}_{2}$. We find surface oxidation effects change stoichiometry material at layer produce large shifting spectral peaks. The experimental evidence is presented and relation studies discussed.
Shrinkage of dog red blood cells (RBC) activates a Na transport pathway that is Cl dependent, amiloride sensitive, and capable conducting Na-proton counterflow. It possible to establish transmembrane gradients for either or protons demonstrate each cation species can drive reciprocal movements the other. The nature coupling between proton was investigated using fluorescent probe diS-C3(5) also by an indirect method in which K through valinomycin channels were used draw inferences about...
Determinants of 45Ca influx, efflux, and 22Na efflux were examined in dog red blood cells. influx is strongly influenced by the Na concentration on either side membrane, being stimulated intracellular inhibited extracellular Na. A saturation curve obtained when Ca plotted as a function medium concentration. The maximum pH (increasing with greater alkalinity) cell volume swelling). Quinidine inhibits influx. Efflux increasing concentrations or medium, effects two ions are mutually exclusive...
Dog red blood cells (RBC) lack a ouabain-sensitive sodium pump, and yet they are capable of volume regulation in vivo. The present study was designed to find vitro conditions under which dog RBC could transport outward, against an electrochemical gradient. Cells were first loaded with chloride water by preincubation hypertonic saline. They then incubated at 37 degrees C media containing physiologic concentrations sodium, potassium, chloride, bicarbonate, glucose, calcium. returned normal...
Red blood cells from mature dogs contain less Na and more K than would be the case if they were in Donnan equilibrium with plasma. They have no ouabain-sensitive pump, their membranes are deficient Na, K-ATPase. Experiments reported which dog red first loaded supranormal quantities of water then reinjected into dog. Over course 26-40 h Na- water-loaded returned to a normal state hydration as judged by density. It is concluded that possess some means correcting swollen status vivo, despite...