A5086754605- Functional Brain Connectivity Studies
- Dementia and Cognitive Impairment Research
- Bacterial Infections and Vaccines
- Advanced Neuroimaging Techniques and Applications
- Health and Wellbeing Research
- Cognitive Functions and Memory
- MRI in cancer diagnosis
- Neurological Disease Mechanisms and Treatments
- Infectious Diseases and Tuberculosis
- Epilepsy research and treatment
- Alzheimer's disease research and treatments
- Amoebic Infections and Treatments
- Cognitive Abilities and Testing
- Neonatal and Maternal Infections
- Diverse Approaches in Healthcare and Education Studies
- Dialysis and Renal Disease Management
- Pneumonia and Respiratory Infections
- Renal and Vascular Pathologies
Inje University Haeundae Paik Hospital
2016-2025
Abstract INTRODUCTION This study aimed to investigate the differential roles of various plasma biomarkers in a stepwise diagnostic strategy for Alzheimer's disease (AD). METHODS A total 2984 participants, including 666 cognitively unimpaired (CU), 2032 with clinical syndrome (ACS), and 286 non‐ACS individuals, were recruited. Plasma amyloid beta (Aβ) 42/40, four phosphorylated tau (p‐tau) epitopes, glial fibrillary acidic protein (GFAP), neurofilament light chain (NfL) levels measured using...
Dementia, particularly Alzheimer's disease, is a significant global health concern, with early diagnosis and treatment development being critical goals. While numerous cohorts have advanced dementia research, there lack of comprehensive data on ethnic differences, for the Korean population. The Korea-Registries to Overcome Dementia Accelerate Research (K-ROAD) aims establish large-scale, hospital-based cohort address this gap, focus understanding disease progression, developing diagnostics,...
The aim of this study was to evaluate the structural and functional connectivities brain network using graph theoretical analysis in neurologically asymptomatic patients with end-stage renal disease (ESRD). We further investigated prevalence cognitive impairment (CI) ESRD analyzed association between measures connectivity function.We prospectively enrolled 40 patients, healthy controls, 20 controls. All subjects underwent diffusion-tensor imaging (DTI) resting-state magnetic resonance...
Background and PurposezzWe investigated the potential role of serum procalcitonin in differentiating tuberculosis meningitis from bacterial viral meningitis, predicting prognosis meningitis.MethodszzThis was a retrospective study 26 patients with meningitis.In addition, 70 49 were included as disease control groups for comparison.The level measured all at admission.Differences demographic laboratory data, including level, analyzed among three groups.In we predictive factors using Glasgow...
Abstract Introduction This study aimed to investigate the association between brain networks and epilepsy development in patients with Alzheimer disease (AD). Methods We enrolled newly diagnosed AD at our hospital who underwent three‐dimensional T1‐weighted magnetic resonance imaging time of diagnosis included healthy controls. obtained cortical, subcortical, thalamic nuclei structural volumes using FreeSurfer applied graph theory obtain global network intrinsic based on BRAPH. Results 25 56...
Our previous study demonstrated that patients with end-stage renal disease had decreased structural and functional brain connectivity, there was a significant association between connectivity cognitive function. The aim of this to evaluate the alterations using graph theoretical analysis in neurologically asymptomatic relatively early-stage chronic kidney (CKD).We enrolled 18 early CKD 28 healthy controls. All subjects underwent diffusion-tension imaging resting magnetic resonance imaging....
We aimed to develop the diagnostic matrix of Seoul Cognitive Status Test (SCST) and compare its performance with traditional paper-and-pencil neuropsychological tests, including Neuropsychological Screening Battery-II (SNSB-II) Korean version Consortium Establish a Registry for Alzheimer's Disease (CERAD-K).