A5075464864- Adipose Tissue and Metabolism
- Diet, Metabolism, and Disease
- Diet and metabolism studies
- Birth, Development, and Health
- Circadian rhythm and melatonin
- Liver Disease Diagnosis and Treatment
- Dietary Effects on Health
- Stress Responses and Cortisol
- Biochemical effects in animals
Hospital Sant Joan de Déu Barcelona
2020-2023
Institut de Recerca Sant Joan de Déu
2020-2021
Sant Joan de Déu Research Foundation
2020
Hospital Civil de Guadalajara
2018
Universidad de Guadalajara
2018
Litter size is a biological variable that strongly influences adult physiology in rodents. Despite evidence from previous decades and recent studies highlighting its major impact on metabolism, information about litter currently underreported the scientific literature. Here, we urge this important should be explicitly stated research articles.
Anthocyanin consumption is linked to benefits in obesity-related metabolic alterations and non-alcoholic fatty liver disease (NAFLD), though the functional role of delphinidin (Dp) yet be established. Therefore, this study examined effects Dp on associated with NAFLD, molecular mechanisms HepG2 cells diet-induced obese mice. Cells incubated palmitate induce lipid accumulation, concomitantly treated Dp, reduced triglyceride accumulation by ~53%, downregulated gene expression CPT1A, SREBF1,...
Childhood obesity is a strong risk factor for adult obesity, type 2 diabetes, and cardiovascular disease. The mechanisms that link early adiposity with late-onset chronic diseases are poorly characterised. We developed mouse model of through litter size reduction. Mice reared in small litters (SLs) insulin resistance, hepatic steatosis during adulthood. liver played major role the development To gain insight into molecular childhood resistance. analysed transcriptome (Affymetrix) control SL...
To study the effect of 18-hydroxy-eicosapentaenoic acid (18-HEPE) and 17-hydroxy-docosahexaenoic (17-HDHA) in a murine model obesity/nonalcoholic fatty liver disease.C57BL/6 mice were fed with standard chow diet (CD) or high-fat, fructose-enriched (HFD) for 16 wk. Then, three groups treated 14 d either, switch (HFD CD), 18-HEPE, 17-HDHA. Weight fasting glucose recorded on weekly basis. Insulin tolerance test was performed at end treatment. Histological analysis (HE Masson's trichrome stain)...
Time restricted feeding (TRF) refers to dietary interventions in which food access is limited during a specific timeframe of the day. TRFs have proven useful improving metabolic health adult subjects with obesity. Their beneficial effects are mediated, part, through modulating circadian rhythm. Nevertheless, translation these onto obese/overweight children and adolescents remains uncharacterized. The objective this study explore feasibility temporal for context childhood