A5056351408- Computational Drug Discovery Methods
- Synthesis and biological activity
- Natural product bioactivities and synthesis
- Medicinal Plants and Neuroprotection
- Phytochemistry and Biological Activities
- Flavonoids in Medical Research
- Pharmacological Effects of Natural Compounds
- Tea Polyphenols and Effects
- SARS-CoV-2 and COVID-19 Research
- Cancer Treatment and Pharmacology
- Advanced Breast Cancer Therapies
- Essential Oils and Antimicrobial Activity
- Chemical Synthesis and Analysis
- Vitamin K Research Studies
- Bioactive Compounds and Antitumor Agents
- Avian ecology and behavior
- Pharmacology and Nanomedicine Research
- Phytochemicals and Antioxidant Activities
- Vitamin C and Antioxidants Research
- Chromatography in Natural Products
- Bacteriophages and microbial interactions
- Enzyme function and inhibition
- Biopolymer Synthesis and Applications
- Poxvirus research and outbreaks
- Estrogen and related hormone effects
University of the Punjab
2020-2024
Minhaj University Lahore
2016
Abstract In the current report, we studied possible inhibitors of COVID-19 from bioactive constituents Centaurea jacea using a threefold approach consisting quantum chemical, molecular docking and dynamic techniques. is perennial herb often used in folk medicines dermatological complaints fever. Moreover, anticancer, antioxidant, antibacterial antiviral properties its compounds are also reported. The Mpro (Main proteases) was docked with different through docking. All including apigenin,...
The present research carried out to estimate the antioxidant activity of Anisomeles indica (L.) O. Kuntze leaves by employing some in vitro methods i.e. free radical scavenging activity, reducing ability and chelating ability.The extract showed an excellent all three mechanisms.TEAC (Trolox equivalent capacity) values A. range from 11.17 ±
Birds exhibit a wide variety of behaviors including foraging behavior which could vary both inter- and intra-specifically. The current study was aimed to investigate different aspects the birds in fields situated at Quaid-e-Azam Campus, University Punjab, Lahore. said campus covers an area about 721 ha has stable ecosystem supports diverse range birds. Three were selected for purposes. first field (F1) characterized by dense vegetation. second (F2) contained relatively less vegetation third...
Drug resistance affects the most effective anti-malarial medications, hence finding new, unique bioactive compounds with strong activity is extremely desirable. Falcipain-2 (2GHU) a protease of plasmodium falciparum and considered as an important target to design antimalarial drugs. Objective: To identify potential novel falcipan-2 inhibitor for effect treatment malaria. Methods: Molecular docking analysis was performed by using different bioinformatic tools check interaction between...
Nuclear factor-κB (NF-κB) represents a family of inducible transcription factors, which regulates large array genes involved in different processes the immune and inflammatory responses. Deregulated NF-κB activation contributes to pathogenic process various diseases such as inflammation cancer. signaling cancer cells is cellular proliferation, angiogenesis, invasion, metastasis, development drug resistance anti-apoptosis. Objective: To identify potent IκBα inhibitors using molecular docking...
Centipeda minima (C. minima), is a medicinally important herb commonly called "Sneeze Weed" and widely distributed in humid areas. In China, Malaysia, Nepal, it used folk medicines for the treatment of rhinitis, nasopharyngeal carcinoma, respiratory disorders, also exhibits antibacterial, antioxidant antiprotozoal activity. Recently discovered that various bioactive molecule C. has strong potential to be neoplasms. Thus, this review, we aim summarize discuss cellular targets anticancer...
The novel strain of coronavirus, SARS-CoV-2, has spread adverse effects on human health with high mortality rates worldwide. SARS-CoV-2 is a severe respiratory disease expressed through positive single stranded RNA enveloped virus. had affected globally and influencing the economy as well. rapidly spreading coronavirus infection discombobulated researchers in perpetuate search for different or effective therapeutic drugs. Most connatural products are proposed to have significant clinical...