P. Maxwell Slepian

ORCID: 0000-0003-0435-4191
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About
Contact & Profiles
Research Areas
  • Musculoskeletal pain and rehabilitation
  • Resilience and Mental Health
  • Anesthesia and Pain Management
  • Pain Management and Opioid Use
  • Connective tissue disorders research
  • Pain Mechanisms and Treatments
  • Opioid Use Disorder Treatment
  • Fibromyalgia and Chronic Fatigue Syndrome Research
  • Pain Management and Placebo Effect
  • Cerebral Palsy and Movement Disorders
  • Pediatric Pain Management Techniques
  • Blood donation and transfusion practices
  • Dermatological and Skeletal Disorders
  • Stroke Rehabilitation and Recovery
  • Shoulder Injury and Treatment
  • Behavioral Health and Interventions
  • Mindfulness and Compassion Interventions
  • Transcranial Magnetic Stimulation Studies
  • Traumatic Brain Injury Research
  • Pain Management and Treatment
  • Optimism, Hope, and Well-being
  • Organ Donation and Transplantation
  • Death Anxiety and Social Exclusion
  • Heart Rate Variability and Autonomic Control
  • Cardiac, Anesthesia and Surgical Outcomes

Toronto General Hospital
2020-2025

University Health Network
2020-2025

University of Toronto
2022-2025

York University
2020-2025

Krembil Foundation
2024

Krembil Research Institute
2024

Ohio University
2015-2020

VA Connecticut Healthcare System
2020

Center for Innovation
2020

Ohio University Lancaster
2014

Abstract Background The fear-avoidance model of chronic pain holds that individuals who catastrophize in response to injury are at risk for pain-related fear and avoidance behavior, ultimately prolonged disability. Purpose Based on the hypothesis predictive power would be enhanced by consideration positive psychological constructs, present study examined inclusion resilience self-efficacy model. Methods Men women (N = 343) experienced a recent episode back were recruited longitudinal online...

10.1093/abm/kaz051 article EN Annals of Behavioral Medicine 2019-11-11

Clinical hypnosis is an effective strategy for managing acute pain in the surgical setting. However, opioid sparing effects of clinical are not as well understood. This pre-registered (NCT03730350) randomized, controlled trial (RCT) examined impact hypnosis, pre- and post-surgery, on consumption during hospitalization measures intensity, interference, depressed mood, anxiety, sleep, catastrophizing. Participants (M = 57.6 years; SD 10.9) awaiting oncologic surgery were randomized to...

10.2147/jpr.s424639 article EN cc-by-nc Journal of Pain Research 2024-01-01

Abstract Evidence-based treatment of chronic pain requires a multidisciplinary approach grounded in the biopsychosocial model. Implementing this within health systems relies on its acceptance by both healthcare providers and patients. While pioneering clinics can serve as model for implementation, systematic effort is needed to share knowledge effectively broadly. In current paper we provide an overview translation initiatives undertaken at our Transitional Pain Service (TPS) Toronto General...

10.1186/s12913-025-12301-y article EN cc-by BMC Health Services Research 2025-01-29

Abstract Past research has indicated that individuals with Ehlers-Danlos Syndromes (EDS) and Generalized Hypermobililty Spectrum Disorder (G-HSD) report psychological psychiatric symptoms, particularly anxiety disorders depressive at much greater rates than the general population. However, these studies have been primarily conducted in small samples European centres. We a retrospective chart review from 1035 consecutive patients (88% female) assessed for EDS/G-HSD GoodHope EDS Clinic Toronto...

10.1186/s13023-025-03550-5 article EN cc-by Orphanet Journal of Rare Diseases 2025-02-14

Introduction Clinical hypnosis has been proposed for post-surgical pain management its potential vagal-mediated anti-inflammatory properties. Evidence is needed to understand effectiveness recovery. Iin this secondary outcome study, it was hypothesized that surgical oncology patients randomized receive perioperative clinical (CH) would demonstrate greater heart-rate variability (HRV) during rest and relaxation at a 1-month post-surgery assessment compared treatment-as-usual group (TAU)....

10.3389/fpain.2024.1354015 article EN cc-by Frontiers in Pain Research 2024-03-08

BACKGROUND In contrast to standard donor retention strategies (e.g., mailings, phone calls, text messages), we developed a brief telephone interview, based on motivational interviewing principles, that encourages blood donors reflect upon their unique motivators and barriers for giving. This study examined the effect of this combined with action coping plan components, motivations. STUDY DESIGN AND METHODS The design was randomly assign receive either telephone‐delivered interview components...

10.1111/trf.13485 article EN Transfusion 2016-01-29

Whereas decades of research have been devoted to psychological factors that confer vulnerability disability and other negative outcomes in the face chronic pain, recent studies begun emphasize characteristics contribute enhanced adaptation better clinical outcomes. Accordingly, present study was conducted as a longitudinal assessment predictive utility pain resilience catastrophizing indicators among patients receiving standardized treatment for pain.Using an observational design, analyses...

10.1037/hea0000877 article EN Health Psychology 2020-04-23

With >700 transplant surgeries performed each year, Toronto General Hospital (TGH) is currently one of the largest adult centers in North America. There a lack literature regarding both identification and management chronic postsurgical pain (CPSP) after organ transplantation. Since 2014, TGH Transitional Pain Service (TPS) has helped manage patients who developed CPSP solid transplantation (SOT), including heart, lung, liver, renal transplants.In this retrospective cohort study, we describe...

10.1097/tp.0000000000004441 article EN Transplantation 2022-12-09

Mobile health platforms have become an important component of pain self-management programs and hundreds mobile applications are commercially available for patients to monitor pain. However, few these been developed in collaboration with healthcare professionals or critically evaluated. Manage My Pain is a user-driven platform by ManagingLife clinician researchers. allows keep "pain record" supports communication this information clinicians. The current report describes user engagement study...

10.1177/2055207620962297 article EN Digital Health 2020-01-01

Abstract Ehlers-Danlos Syndrome (EDS) are a heterogeneous group of genetic connective tissue disorders, and typically manifests as weak joints that subluxate/dislocate, stretchy and/or fragile skin, organ/systems dysfunction, significant widespread pain. Historically, this syndrome has been poorly understood often overlooked. As result, people living with EDS had difficulty obtaining an accurate diagnosis appropriate treatment, leading to untold personal suffering well ineffective health...

10.1186/s13023-021-01962-7 article EN cc-by Orphanet Journal of Rare Diseases 2021-08-10

Introduction It has been well described that a small but significant proportion of patients continue to use opioids months after surgical discharge. We sought evaluate postdischarge opioid who were seen by Transitional Pain Service compared with controls. Methods conducted retrospective cohort study using administrative data individuals underwent surgery in Ontario, Canada from 2014 2018. Matched pairs created matching other academic hospitals Ontario not enrolled Service. Segmented...

10.1136/rapm-2023-104709 article EN Regional Anesthesia & Pain Medicine 2023-11-08

Pediatric chronic post-surgical pain is a surgical complication associated with various levels of functional limitation. Two commonly used measures limitations in youth are the Functional Disability Inventory (FDI) and PROMIS Pain Interference Scale (PPIS), where former general, latter, specific. The aim present study was to prospectively compare pre-surgical parent risk factors for limitations, assessed by FDI PPIS, 12 months after major pediatric surgery. Risk PPIS were compared 79 dyads...

10.3390/children8050360 article EN cc-by Children 2021-04-30

Post-viral pain syndrome, also known as post-viral syndrome (PVS), is a complex condition characterized by persistent pain, fatigue, musculoskeletal neuropathic neurocognitive difficulties, and sleep disturbances1,2 that can occur after an individual has recovered from viral infection. Much remains unknown regarding the pathophysiology of syndromes few studies have provided comprehensive summary condition, agents cause it, successful treatment modalities. With COVID-19 pandemic continuing to...

10.1080/24740527.2023.2272999 article EN cc-by Canadian Journal of Pain 2023-07-30

Introduction The Transitional Pain Service (TPS) is an innovative, personalized approach to postsurgical opioid consumption and pain management. objectives of this study were identify trajectories intensity within 12 months after initiating treatment through the TPS, biopsychosocial factors associated with trajectory membership, examine relationship between membership other outcomes interest over same 12-month period. Methods Consecutive patients referred TPS included in present (n=466)....

10.1136/rapm-2024-105344 article EN Regional Anesthesia & Pain Medicine 2024-07-30

BACKGROUND Based on the hypothesis that self‐determined motivation is associated with an increased likelihood of future behavior, present study examined ability a motivational interview to promote internal for giving blood and donation attempts. STUDY DESIGN AND METHODS A sample 484 recent whole‐blood double red cell donors (62.4% female; age = 30.2 ± 11.8 years) were randomly assigned either telephone‐delivered or control call approximately 6 weeks after donating. Several before again 1...

10.1111/trf.14203 article EN Transfusion 2017-07-03

BACKGROUND Interventions intended to motivate donors return can be costly and time consuming. The current study examined the effect of a Web‐based automated interview, informed by motivational interviewing self‐determination theory, on donor intention, motivation, behavior in sample highly experienced donors. STUDY DESIGN AND METHODS Approximately 1 week after donating, 1177 whole blood (mean prior donations, 35.5; mean age, 46.9 years; 66.3% female) participated which they were randomly...

10.1111/trf.15402 article EN Transfusion 2019-06-14
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