A5088524018- Vestibular and auditory disorders
- Ear Surgery and Otitis Media
- Hearing, Cochlea, Tinnitus, Genetics
- Nasal Surgery and Airway Studies
- Meningioma and schwannoma management
- Obstructive Sleep Apnea Research
- Facial Nerve Paralysis Treatment and Research
- Sinusitis and nasal conditions
- Tracheal and airway disorders
- Ear and Head Tumors
- Hearing Loss and Rehabilitation
- Ophthalmology and Eye Disorders
- Head and Neck Surgical Oncology
- Gastroesophageal reflux and treatments
- Respiratory and Cough-Related Research
- Head and Neck Anomalies
- Salivary Gland Tumors Diagnosis and Treatment
- Neurofibromatosis and Schwannoma Cases
- Nerve injury and regeneration
- Airway Management and Intubation Techniques
- Neuroscience of respiration and sleep
- Oral and Maxillofacial Pathology
- Reconstructive Facial Surgery Techniques
- Allergic Rhinitis and Sensitization
- Otitis Media and Relapsing Polychondritis
Campus Bio Medico University Hospital
2000-2025
Università Campus Bio-Medico
2014-2024
Johns Hopkins Medicine
2017
Johns Hopkins University
2017
Merck Serono (Switzerland)
2010
Sapienza University of Rome
2005
Università Cattolica del Sacro Cuore
1985-2004
Catholic University of America
1990
Obstructive sleep apnea syndrome (OSAS) is a complex chronic clinical syndrome, characterized by snoring, periodic apnea, hypoxemia during sleep, and daytime hypersomnolence. It affects 4-5% of the general population. Racial studies chromosomal mapping, familial twin have provided evidence for possible link between OSAS genetic factors also most risk involved in pathogenesis are largely genetically determined. A percentage 35-40% its variance can be attributed to factors. likely that...
Summary Background Gastro‐oesophageal reflux disease (GERD) may contribute to the onset of chronic cough (CC); however, multichannel intraluminal impedance‐pH (MII‐pH) monitoring is often within normal range and response proton pump inhibitors (PPIs) unsatisfactory. The measure impedance baseline (IB) increases sensitivity MII‐pH in patients with typical symptoms. Aim To evaluate role variables, including IB, predicting PPI define characteristics pattern CC patients. Methods Prospectively...
This is a report of 12 cases clival chordomas that were surgically treated at the Catholic University Medical School, Rome, Italy, over 7-year period. The study emphasizes role transsphenoidal approach. group included seven men and five women whose ages ranged from 26 to 80 years (mean 49.8 years). Diplopia was most common presenting symptom (eight cases). tumor involved upper middle clivus in cases, five, lower two cases. One patient developed spinal metastasis. On histological examination,...
In this study we evaluate the postoperative facial nerve function after vestibular schwannoma (VS) surgery and analyze factors that cause it. We included 97 consecutive patients undergoing surgical excision of sporadic unilateral VS. Patient tumor characteristics, approaches, function, extent removal, perioperative complications are all analyzed through standardized systems. Four different approaches used: translabyrinthine, retrolabyrinthine, retrosigmoid, middle cranial fossa. Anatomic...
Background: Refractory Meniere's disease (MD) is a disabling disease; moreover, selective vestibular neurectomy (VN), in these selected cases of drug-resistant pathology, can be considered an alternative surgical option order to preserve hearing and facial nerve function.
To investigate the effect of nasal obstruction surgery on eustachian tube function and middle ear ventilation.Prospective study.University Campus Bio-Medico Rome.Forty consecutive patients who underwent were evaluated for ventilation tubal function.Pre- postoperative Valsalva Toynbee tests, tympanometry fullness sensation both ears each patient.Results tests significantly better than preoperative ones (90% versus 46%; P<0.001). No significant difference in tympanometric values was found. The...
The objective of the study was to evaluate efficacy three therapeutic strategies (Semont maneuver, flunarizine, and no treatment) in patients with benign paroxysmal positional vertigo.Randomized prospective trial.One hundred fifty-six consecutive older than 60 years age who were affected by vertigo posterior semicircular canal enrolled. diagnosis made on basis history recurrent sudden crisis positional-induced typical nystagmus after Dix-Hallpike positioning maneuver. Patients randomly...
Background This study was designed to prospectively evaluate the role of nebulized hyaluronic acid (HA) given for 10 days/mo over 3 months as adjunct treatment minimize symptoms and preventing exacerbation chronic rhinosinusitis (CRS). Methods Thirty-nine eligible patients were randomized receive 9-mg sodium hyaluronate nasal washes plus saline solution (21 patients) or 5 mL alone (18 patients), according an open-label, parallel-group design, with blind observer assessment. A questionnaire...
The aim of the study was to evaluate hearing thresholds in 38 patients with rheumatoid arthritis, divided according disease activity into active (group A, n = 20) and non-active B, 18) patients. Pure tone audiometry, tympanometry complete rheumatological assessment were performed. All presented poorer auditory compared controls. Patients group A had both air bone conduction than B (although not statistically significant), most groups an air-bone (a-b) gap. No significant difference middle...
Background. The endoscopic endonasal transclival approach (EETCA) is a minimally-invasive technique allowing direct route to the base of implant clival lesions with reduced brain and neurovascular manipulation. On other hand, it associated potentially severe complications related difficulties in reconstructing large skull defects high risk postoperative cerebrospinal fluid (CSF) leakage. aim this paper describe precise layer by reconstruction EETCA including suture mucosa as an additional...
Acrylic hydrogels, like the polymer of 2-hydroxyethyl methacrylate, are biocompatible, mechanically stable, porous materials that can be coated with collagen or laminin acting as bioadhesive substrates. Poly- methacrylate sponges have been proposed for restoring anatomical continuity damaged neural structures. In present work, ability poly-2-hydroxyethylmethacrylate to provide injured spinal cord neurons a conductive substrate their regenerating axons was investigatedin 32 adultWistar rats....