A5075814589- Acupuncture Treatment Research Studies
- Traditional Chinese Medicine Studies
- Healthcare and Venom Research
- Medical Research and Treatments
- Osteoarthritis Treatment and Mechanisms
- Biochemical effects in animals
- Complementary and Alternative Medicine Studies
- Dietary Effects on Health
- Cancer-related molecular mechanisms research
- Pharmacological Effects of Natural Compounds
- Regulation of Appetite and Obesity
- Inflammatory mediators and NSAID effects
- Stress Responses and Cortisol
- Pain Management and Placebo Effect
- Mycobacterium research and diagnosis
- Sirtuins and Resveratrol in Medicine
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Intensive Care Unit Cognitive Disorders
- Respiratory Support and Mechanisms
- Anesthesia and Neurotoxicity Research
- Public Health and Nutrition
- Tryptophan and brain disorders
- Vagus Nerve Stimulation Research
- Gastrointestinal motility and disorders
- Pain Mechanisms and Treatments
Chinese Academy of Medical Sciences & Peking Union Medical College
2020-2024
Guangzhou Medical University
2024
State Key Laboratory of Cardiovascular Disease
2024
Zhejiang University
2015-2023
Xianning Central Hospital
2021-2023
Hubei University of Chinese Medicine
2013-2023
National Natural Science Foundation of China
2023
Hubei University
2023
Northwest University
2018-2023
Beijing University of Chinese Medicine
2012-2022
Abstract MicroRNAs (miRNAs) encapsulated within exosomes can serve as essential regulators of intercellular communication and represent promising biomarkers several aging-associated disorders. However, the relationship between exosomal miRNAs osteoarthritis (OA)-related chondrocytes synovial fibroblasts (SFCs) remain to be clarified. Herein, we profiled fluid-derived explored effects derived from SFCs on chondrocyte inflammation, proliferation, survival, further assessed their impact...
Abstract Background The pathophysiology of cognitive impairment in patients with the major depressive disorder (MDD) may involve neuroinflammation mediated by cytokines. Objective aim this study was to examine serum interleukin-6 (IL-6) levels, sustained attention, and their association MDD. Methods Thirty MDD 30 healthy controls were enrolled case-control study. Sustained attention measured using Rapid Visual Information Processing (RVP) task Cambridge Neuropsychological Tests Automated...
Chronic obstructive pulmonary disease (COPD) is one of the most common lung diseases. It a chronic inflammatory process characterised by airway obstruction and progressive inflammation, associated with difficulty breathing insensitivity to corticosteroid therapy. Although there some preliminary evidence suggest beneficial effect acupuncture on COPD, its mechanism action has not been investigated. Our aim was examine anti-inflammatory effects in rat model COPD induced exposure cigarette smoke...
<b><i>Objective:</i></b> To investigate the anorexigenic and anti-obesity effectiveness of electroacupuncture (EA) on high-fat-diet-induced (HFDI) obese rats with insulin resistance (IR) to reveal possible mechanisms EA affecting SIRT1 (silent mating type information regulation 2 homolog 1) in central nervous system (CNS). <b><i>Methods:</i></b> We divided 60 into 6 groups. All interventions, including intracerebroventricular administration,...
Fibroepithelial polyps (FEPs) are benign mesenchymal skin tumors that usually occur in folds. FEPs clinically vary appearance and size; typically, small papillomatous grow <5 cm; however, large pedunculated forms can rarely >5 cm, called giant FEPs. In females during reproductive years, the genitals, commonly vagina vulva cervix. The present case is of a 27-year-old sexually active nulliparous, who presented with complaint large, soft, single bag-like growth from her left labium majus. It...
Acupuncture has been indispensable in Chinese medicine. However, its function still remains elusive. This paper studies the effect of acupuncture ischemia stroke treatment using Sprague Dawley rat animal model. We induced focal cerebral rats middle artery occlusion (MCAO) procedure. For each real group (n = 63), sham acupoint 62) and blank control 30), we acquired 3-D fluorodeoxyglucose-microPET images at baseline, after MCAO treatment, respectively. Then, measured changes injury-volume...
Obesity is a worldwide public health problem. Currently, increasing evidence suggests acupuncture and related therapies are effective for obesity. This network meta-analysis (NMA) was performed to compare the effectiveness of different therapies. We searched potential randomized controlled trials (RCTs) in three international databases. Thirty-four involving 2283 participants were included. Pairwise showed that superior lifestyle modification placebo reducing weight body mass index (BMI)....
Moxibustion is the main alternative medicine treatment that has been beneficial to diabetic peripheral neuropathy (DPN), a common complication secondary microvascular injury. However, underlying protective mechanism of moxibustion against neuroinflammation remains unclear. We hypothesized treats DPN by regulating balance nuclear factor-2 erythroid-related (Nrf2)-nuclear factor-kappa light chain enhancer B cells (NF-кB). In vivo, diabetes was induced in rats injecting streptozotocin (STZ; 60...
Diabetic nephropathy (DN) is one of the most devastating diabetic microvascular complications. It has previously been observed that iron metabolism levels are abnormal in patients. However, mechanism by which affect DN poorly understood. This study was designed to evaluate role iron-chelator deferoxamine (DFO) improvement DN. Here, we established a rat model induced diets high carbohydrates and fat streptozotocin (STZ) injection. Our data demonstrated DFO treatment for three weeks greatly...
Acupuncture is an emerging alternative therapy that has been beneficial for the pain of osteoarthritis (OA). However, underlying mechanism protective effect remains unclear. MCP1/CCR2 axis can be stimulated in various periods OA, and we hypothesize acupuncture may treat OA by regulating axis. This study aimed to explore at points ST35 ST36 on effects hyperalgesia cartilage rats including expression chemokines, nerve growth factor (NGF), inflammatory-related proteins. was induced male...
Acupuncture has been practiced to treat neuropsychiatric disorders for a thousand years in China. Prevention of disease by acupuncture and moxibustion treatment, guided the theory Chinese acupuncture, gradually draws growing attention nowadays investigated role prevention treatment mental such as AD. Despite its well-documented efficacy, biological action remains greatly invalidated. Here, we sought observe whether preventive electroacupuncture during aging process could alleviate learning...
We aim to explore whether acupuncture inhibits inflammation and bone destruction in rat model monosodium iodoacetate (MIA)-induced knee osteoarthritis (KOA) by 18F-fluorodeoxyglucose (18F-FDG) small-animal positron emission tomography (PET) micro-computed (CT) imaging.KOA was induced rats intra-articular injection MIA (2 mg/50 μL) through the right of rats. Forty male Sprague Dawley weighing 280 340 g (12 weeks old) were randomly divided into four groups including Control group, KOA plus...
Inflammation serves a critical role in the pathophysiology of intracerebral hemorrhage (ICH)-induced brain injury. Eupatilin, pharmacologically active flavone derived from Artemisia sp., has been reported to have antioxidant, anti-inflammatory, anti-allergic and antitumor activities. However, effect eupatilin ICH not well studied. The aim present study was investigate on ICH-induced microglial inflammation. MTT Transwell migration assay results revealed that significantly inhibited...
Sleep deprivation (SD) adversely affects brain function and is accompanied by frequency-dependent changes in electroencephalograms (EEGs). Recent studies have suggested that acupuncture an emerging alternative therapy for SD. However, the involvement of frequency EEG α β waves protective effect against SD remains unknown. The present study investigated instant at GV20 on insomnia analyzing using electroencephalography a model sleep deprivation. A total 16 rats (Wistar; male; weight, 340±10...
Objective: Electroacupuncture (EA) pretreatment appears useful in the treatment of chronic myocardial ischemia (CMI). The goal this study was to investigate effect EA preconditioning on regulation hypoxia-inducible factor (HIF)-1α and vascular endothelial growth (VEGF) proteins a CMI model regeneration. Methods: A established by subcutaneous injection isoprinosine hydrochloride (ISO) for 14 days 45 Wistar rats, which had been randomly divided into group ( n = 15), pretreated with sham 21...
Electroacupuncture (EA) therapy has been widely accepted as a useful therapeutic technique with low or no risk in the clinical prevention of cardiac hypertrophy. However, signaling transduction mechanism underlying this effect remains unclear. The current study investigates effects EA on pathways myocardial hypertrophy (MH) rats. Up to 40 3-month-old Sprague-Dawley (SD) rats were randomly divided into normal, model, PC6 (Neiguan), and LI4 (Hegu) groups, ten each group. All except for normal...