Zhongyu Zhou

ORCID: 0000-0003-3288-4827
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Research Areas
  • Acupuncture Treatment Research Studies
  • Healthcare and Venom Research
  • Traditional Chinese Medicine Studies
  • Diet and metabolism studies
  • Pelvic floor disorders treatments
  • Adipose Tissue and Metabolism
  • Dietary Effects on Health
  • Complementary and Alternative Medicine Studies
  • Allergic Rhinitis and Sensitization
  • Anorectal Disease Treatments and Outcomes
  • Pharmacology and Obesity Treatment
  • Urinary Bladder and Prostate Research
  • Medical Research and Treatments
  • Adipokines, Inflammation, and Metabolic Diseases
  • Asthma and respiratory diseases
  • Neurological Disease Mechanisms and Treatments
  • Metabolomics and Mass Spectrometry Studies
  • Menopause: Health Impacts and Treatments
  • Dermatology and Skin Diseases
  • Musculoskeletal pain and rehabilitation
  • Ovarian function and disorders
  • RNA modifications and cancer
  • Gut microbiota and health
  • Infrared Thermography in Medicine
  • Olfactory and Sensory Function Studies

Hubei Provincial Hospital of Traditional Chinese Medicine
2012-2025

Hubei University of Chinese Medicine
2013-2025

Hubei University
2012-2024

Sun Yat-sen University
2022

Sun Yat-sen University Cancer Center
2022

China Association of Acupuncture-Moxibustion
2021

Hubei Provincial Women and Children's Hospital
2021

State Administration of Traditional Chinese Medicine of the People's Republic of China
2021

Weatherford College
2021

Harbin Medical University
2015-2019

<h3>Importance</h3> Electroacupuncture involving the lumbosacral region may be effective for women with stress urinary incontinence (SUI), but evidence is limited. <h3>Objective</h3> To assess effect of electroacupuncture vs sham SUI. <h3>Design, Setting, and Participants</h3> Multicenter, randomized clinical trial conducted at 12 hospitals in China enrolling 504 SUI between October 2013 May 2015, data collection completed December 2015. <h3>Interventions</h3> Participants were randomly...

10.1001/jama.2017.7220 article EN JAMA 2017-06-27

Acupuncture has been used for chronic constipation, but evidence its effectiveness remains scarce.To determine the efficacy of electroacupuncture (EA) severe functional constipation (CSFC).Randomized, parallel, sham-controlled trial. (ClinicalTrials.gov: NCT01726504).15 hospitals in China.Patients with CSFC and no serious underlying pathologic cause constipation.28 sessions EA at traditional acupoints or sham (SA) nonacupoints over 8 weeks.The primary outcome was change from baseline mean...

10.7326/m15-3118 article EN Annals of Internal Medicine 2016-09-12

Abstract Objective To assess the efficacy of manual acupuncture as prophylactic treatment for naive patients with episodic migraine without aura. Design Multicentre, randomised, controlled clinical trial blinded participants, outcome assessment, and statistician. Setting Seven hospitals in China, 5 June 2016 to 15 November 2018. Participants 150 Interventions 20 sessions at true points plus usual care, non-penetrating sham heterosegmental non-acupuncture or care alone over 8 weeks. Main...

10.1136/bmj.m697 article EN cc-by-nc BMJ 2020-03-25

INTRODUCTION: This multicenter, randomized, noninferiority trial compared electroacupuncture with prucalopride for the treatment of severe chronic constipation (SCC). METHODS: Participants SCC (≤ 2 mean weekly complete spontaneous bowel movements [CSBMs]) were randomly assigned to receive either 28-session over 8 weeks follow-up without 24 or (2 mg/d before breakfast) 32 weeks. The primary outcome was proportion participants ≥3 CSBMs 3–8, based on modified intention-to-treat population, −10%...

10.14309/ajg.0000000000001050 article EN The American Journal of Gastroenterology 2020-12-03

Polymorphisms of microRNA (miRNA), as a novel mechanism, are closely associated with disease states by interfering miRNA function. Direct correlations have been identified between single-nucleotide polymorphisms (SNPs) in miRNA, but the effect on type 2 diabetes mellitus (T2DM) onset among Chinese population remains unclear. Therefore, aim this study was to identify common SNPs miR-27a, miR-146a, and miR-124a T2DM population, well explore diabetic pathological mechanisms impact environmental...

10.4103/0366-6999.151112 article EN cc-by-nc-nd Chinese Medical Journal 2015-02-09

To observe the effect of electroacupuncture (EA) on hypothalamic liver kinase B1 (LKB1)/AMP-activated protein (AMPK) signaling pathway, sympathetic nerve activity and browning white adipose tissue (WAT) in obese mice, so as to explore possible central mechanisms EA improving obesity. C57BL/6J male mice were divided into normal group (n=8) high fat diet (n=30) randomly, fed by for 8 weeks, respectively. In group, with body weight over 20% heavier than that considered mice. The model groups...

10.13702/j.1000-0607.20240109 article EN PubMed 2025-04-25

Obesity is a worldwide public health problem. Currently, increasing evidence suggests acupuncture and related therapies are effective for obesity. This network meta-analysis (NMA) was performed to compare the effectiveness of different therapies. We searched potential randomized controlled trials (RCTs) in three international databases. Thirty-four involving 2283 participants were included. Pairwise showed that superior lifestyle modification placebo reducing weight body mass index (BMI)....

10.1155/2018/9569685 article EN cc-by Evidence-based Complementary and Alternative Medicine 2018-01-01

Meta-analysis of GWAS in East Asian populations had established 10 loci that were associated with type 2 diabetes. Eight them genome-wide significance and two a border line association. Since these data have not been studied an independent Han Chinese population, we aimed to investigate the association susceptibility diabetes population. We executed case-control study 000 by SNPscan method. Firstly, repetitive sequences assessed. Next, investigated 8 SNPs out constructed GRS those SNPs....

10.18388/abp.2018_2632 article EN cc-by Acta Biochimica Polonica 2019-05-30

UBE2E2 encodes ubiquitin-conjugating enzyme E2E2, which plays an important role in the synthesis and secretion of insulin. Two previous studies indicated that SNPs were associated with risk for type 2 diabetes mellitus (T2DM) Japanese Korean populations, respectively. We examined association one SNP this gene, rs7612463, T2DM 1957 Han participants northeastern China, using SNPscan(TM) Kit. rs7612463 genotype was significantly under various genetic models, including additive model (P =...

10.18388/abp.2014_936 article EN cc-by Acta Biochimica Polonica 2015-01-01

This study aimed to examine the efficacy and safety of acupoint catgut embedding (ACE) for obesity over a 16-week treatment period using sham stimulation as control.A multicenter, randomised, parallel, sham-controlled trial was conducted from February 10, 2017, May 15, 2018. Men with waistlines ≥85 cm women ≥80 at three sites were randomised receive eight sessions (over 16 weeks) ACE (n = 108) or skin penetration acupoints. The embedded once every two weeks alternating sets follow-up lasted...

10.1155/2022/4780019 article EN Evidence-based Complementary and Alternative Medicine 2022-02-27

To observe the effects of moxibustion on intestinal barrier function and Toll-like receptor 4 (TLR4)/nuclear factor-κB p65 (NF-κB p65) signaling pathway in obese rats explore mechanism intervention obesity.

10.13703/j.0255-2930.20230529-k0003 article EN PubMed 2024-04-12

Background: Acupuncture has been found to be effective for reducing body weight (BW) with few adverse effects. Objective: The aim of this study was evaluate the effect auricular acupressure plus exercise in primary obese women a randomized controlled clinical trial. Design, Setting, and Patients: Sixty Chinese (ages 18–54) obesity (body mass index [BMI] ≥25 waist circumference [WC] ≥80 cm) were enrolled study. Intervention: patients randomly assigned 2 groups: Group A B. Patients (n=30)...

10.1089/acu.2012.0881 article EN Medical Acupuncture 2012-11-14

To analyze the core acupoints and compatibility of electroacupuncture (EA) for simple obesity based on complex network technique, to explore usage EA waveform.The clinical research literature regarding published from January 1980 June 2016 were searched in PubMed, CNKI, WanFang, VIP, CBM TCM online database establish a prescription obesity. The Matlab2014a software was used perform center analysis cluster analysis, points conducted. Gephi 9.1 demonstrate diagram further waveform.Totally 238...

10.13703/j.0255-2930.2018.03.028 article EN PubMed 2018-03-12

Abstract Background: Obesity is a chronic metabolic disease in which patients are overweight due to the excessive accumulation of fat body. As subtype acupuncture, catgut embedding at acupoints has increased clinical application for obesity. The aim this study evaluate effectiveness and safety acupoint therapy simple Methods analysis: Electronic searches Cochrane Library, PubMed, Springer Medline, EMBASE, Web Science, China National Knowledge Infrastructure (CNKI), Wan-Fang Data (WANFANG),...

10.1097/md.0000000000023728 article EN cc-by-nc Medicine 2020-12-17

To investigate the effect of electroacupuncture (EA) plus treadmill exercise on expression peroxisome proliferator activated receptor γ coactivator 1α(PGC-1α), Irisin, AMP-activated protein kinase (AMPK) in skeletal muscle diet-induced obesity (DIO) rats, so as to explore its mechanism underlying body reduction promotion.Forty-two male SD rats were divided into normal diet (control, n=10), high fat (model), EA, and EA (combination) groups (n=8 each latter 4 groups). The model was established...

10.13702/j.1000-0607.180460 article EN PubMed 2019-07-25

To observe the therapeutic effect of electroacupuncture (EA) and acupoint catgut embedding in treatment simple obesity.Simple obesity patients were randomized into EA group (7 men 36 women, 21-42 years age) (4 37 22-41 age). Hz/20 Hz, a tolerable strength) was applied to main acupoints Zhongwan (CV12), bilateral Tianshu (ST25), Daheng (SP15), Daimai (GB26), Shuidao (ST28), Zhigou (TE6), Yinlingquan (SP9), Zusanli (ST36), Fenglong (ST40), Sanyinjiao (SP6), some auxiliary for 30 min, once...

10.13702/j.1000-0607.170768 article EN PubMed 2019-01-25
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