A5089278733- Asymmetric Hydrogenation and Catalysis
- X-ray Diffraction in Crystallography
- Synthetic Organic Chemistry Methods
- Crystallization and Solubility Studies
- Chemical Synthesis and Analysis
- Nanomaterials for catalytic reactions
- Asymmetric Synthesis and Catalysis
- Synthesis and Biological Evaluation
- Organometallic Complex Synthesis and Catalysis
- Carbon dioxide utilization in catalysis
- Catalysis for Biomass Conversion
- Neurotransmitter Receptor Influence on Behavior
- Cyclopropane Reaction Mechanisms
- Photochemistry and Electron Transfer Studies
- Zebrafish Biomedical Research Applications
- Electrochemical Analysis and Applications
- Luminescence and Fluorescent Materials
- Receptor Mechanisms and Signaling
- Ferrocene Chemistry and Applications
- Molecular Sensors and Ion Detection
- Crystallography and molecular interactions
- Chemical synthesis and alkaloids
- Electron Spin Resonance Studies
- Parkinson's Disease Mechanisms and Treatments
- Multicomponent Synthesis of Heterocycles
University of Chile
2009-2024
Universidad Bernardo O'Higgins
2017-2020
Universidad de Santiago de Chile
2015-2018
Faculty (United Kingdom)
2016
Universidad Central
2016
Leibniz Institute for Catalysis
2011-2014
Millennium Institute for Integrative Biology
2013
Abstract Recent developments in the synthesis of chiral phosphorus ligands are summarized. Main emphasis is given to multitude protocols for their starting from compounds pool or by using other easily available materials. Besides mono‐ and bidentate P‐ligands hybrid bearing N, O, olefinic groups as second ligating units addressed. The syntheses new P‐chirogenic ligands, well with supramolecular structures likewise reviewed. In appropriate cases related privileged comparison. When available,...
The rhodium-catalyzed hydroformylation of methyl oleate (MO) with new monodentate phosphoramidite ligands 1a–d is investigated here. are characterized by lactam rings different size (four- to seven-membered rings). In mild conditions (synthesis gas pressure: 30 bar, 80 °C), the rhodium catalysts based on P-azetidinone 1a gave within 6 h complete conversion and produced mainly 9- 10-formylstearate (MFS) 99% chemoselectivity. hydrolysis test, was also most stable. This additionally confirmed...
Highly stereoselective intramolecular imino-Diels–Alder reaction without any catalyst in water and under microwave irradiation for the synthesis of complex organic systems.
The mono N-alkylation of arylamines using alkylamines as alkyl group donors has been scarcely investigated. In this work, we report the several (52–95%) catalyzed by complex ruthenium-triphos in presence Al(OTf)3. Moreover, highly reductant ability catalyst system allows tandem reduction/N-alkylation nitrobenzenes good yields (up to 80%). addition, can be recycled after three reaction cycles without loss activity.
The electrochemical reduction of nitroarenes allows direct access to manifold nitrogen containing heterocycles. This work reports the simple and electro-organic synthesis 18 different examples 2
The synthesis of fused benzoxepines relies on the use complex substrates and methodologies. Herein, we report our experimental theoretical findings about an unprecedented Rauhut-Currier-type reaction catalyzed by Cs
A systematic experimental and theoretical study of the intermolecular Aza-Diels–Alder reaction using 5-aminopyrrole as a building block shows that commonly accepted endo selectivity, ruled by controversial secondary orbital interactions, are overcome non-covalent interactions affording to unusual exo adduct. Additionally, regioselectivity is also influenced for such interactions. The starting materials easily prepared, use water solvent great achievement development cleaner synthetic methodologies.
Herein, we report an efficient and highly selective method for the reduction of aromatic, heteroaromatic halonitro compounds using readily available cost-effective Ru/C as a catalyst along with unconventional CaH2 source hydride. In most cases corresponding anilines can be obtained by simple filtration without further purification. The use 2-MeTHF operational work-up constitute valid alternative to previous methodologies.
The use of biomass as a new platform chemical substrates has become subject intensive research. In this article the selective functionalization and isomerization allylbenzenes by transfer hydroformylation with formaldehyde is reported.
A series of diphosphoramidites has been synthetized with a piperazine, homopiperazine, and an acyclic 1,2-diamine unit in the backbone. New compounds were tested alongside related N-acyl phosphoramidites as ligands Rh-catalyzed hydroformylation n-octenes to investigate their influence on activity regioselectivity. subsequent study hydrolysis stability revealed that most stable induced highest catalytic reaction.
Abstract The high content of oxygenated compounds present in the biomass constitutes an important drawback to transforming it into a suitable alternative chemical entities. In this sense, hydrodeoxygenation (HDO) is reaction for cleavage strong C−O bond. Herein we report our findings about use Pd/C and CaH 2 system HDO several aromatic aliphatic aldehydes ketones.
Reduction of carbonyl moieties to the corresponding alcohol using simply hydrazine hydrate has been considerably unfeasible until now due well-known condensation reaction. However, herein, we report that an excess 20-fold equivalents, reduction proceeds in excellent yields. 1H NMR study reaction and density functional theory (DFT) calculations indicate final fate hemiaminal intermediate is crucial obtain or hydrazone.