Kannan Chandrasekar

ORCID: 0000-0003-0453-167X
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About
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Research Areas
  • Viral Infections and Immunology Research
  • Viral gastroenteritis research and epidemiology
  • Hepatitis C virus research
  • Precipitation Measurement and Analysis
  • Animal Virus Infections Studies
  • Hepatitis Viruses Studies and Epidemiology

Ghent University Hospital
2024

Translational Health Science and Technology Institute
2024

Abstract Recent advances in vaccine technology have positioned messenger RNA (mRNA) vaccines as safe and reliable options for human use. Conventionally, mRNA were designed using linear or self-amplifying (SAM), the latter considered to be superior. However, limited success was achieved with SAM during COVID-19 pandemic. Further, studies on Circular (Circ-RNA) against SARS-CoV-2, Ebola monkey pox proved their efficacy. Circ-RNAs are highly stable, neither they induce inflammatory response nor...

10.1101/2024.08.23.609366 preprint EN cc-by-nc-nd bioRxiv (Cold Spring Harbor Laboratory) 2024-08-27

Local and distant archives of observed weather data present unique opportunities for scientists to obtain long time series the historical hydrology climate many regions world. Unfortunately, most these observational records are still to-date available only on paper, thus require digitization transcribing machine-readable formats facilitate analysis hydroclimatic trends. Here we discuss rescue efforts recorded at 36 stations in Democratic Republic Congo from early 1950’s to-date. We...

10.5194/egusphere-egu24-9889 preprint EN 2024-03-08

Abstract Hepatitis E virus (HEV) is a major cause of acute viral hepatitis in lower- and middle-income countries. HEV infection may lead to liver failure, chronic disease high mortality pregnant women. Antiviral therapy not standard treatment for patients. Computational biology tools promise revolutionize the antiviral drug discovery. Here, we analyzed transcriptome data infected primary human hepatocyte (PHH)-cells through connectivity map database applied control theory on functional...

10.1101/2024.06.21.600064 preprint EN bioRxiv (Cold Spring Harbor Laboratory) 2024-06-23
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