A5058490141- Parkinson's Disease Mechanisms and Treatments
- Neurological disorders and treatments
- Sleep and Wakefulness Research
- Cardiovascular Syncope and Autonomic Disorders
- Obstructive Sleep Apnea Research
- Sleep and related disorders
- Neurology and Historical Studies
- Biochemical Analysis and Sensing Techniques
- Genetics and Neurodevelopmental Disorders
- Botulinum Toxin and Related Neurological Disorders
- Traumatic Brain Injury Research
- Nicotinic Acetylcholine Receptors Study
- Cardiovascular Health and Disease Prevention
- Balance, Gait, and Falls Prevention
- Amyotrophic Lateral Sclerosis Research
- Epilepsy research and treatment
- Heart Rate Variability and Autonomic Control
- History of Medical Practice
- Regulation of Appetite and Obesity
- Medical and Biological Sciences
- Restless Legs Syndrome Research
- Neuroscience and Neural Engineering
- Sympathectomy and Hyperhidrosis Treatments
- Clinical Reasoning and Diagnostic Skills
- Advances in Oncology and Radiotherapy
The University of Texas Health Science Center at San Antonio
2023-2025
The University of Texas Health Science Center at Houston
2024-2025
The University of Texas at San Antonio
2024
St. Elizabeth's Medical Center
2020-2024
Boston University
2012-2023
Boston Medical Center
2011-2019
University Medical Center
2019
Noran Neurological Clinic
2013-2016
Automated sleep detection in movement disorders may allow monitoring sleep, potentially guiding adaptive deep brain stimulation (DBS).
Deep brain stimulation (DBS) is an important clinical therapeutic tool to control motor symptoms of Parkinson's disease (PD) for many patients whose are not well controlled by medication alone [1]. DBS therapy involves the delivery electrical current through electrode that surgically placed in brain, traditionally subthalamic nucleus (STN) or globus pallidus internus (GPi). Recent technology has allowed these devices only deliver current, but also measure local field potentials (LFPs). LFPs...
Despite data supporting the rapid adoption of telehealth in delivery clinical care North America, implementation visits research studies has faced critical barriers. These challenges include: (1) variations state licensure requirements for telehealth; (2) disparities access to among disadvantaged populations; (3) lack consistency individual Investigational Review Boards (IRBs). Each barrier prevents systematic conversion protocols include visits. The Parkinson's Foundation and members...
The brain plays central role in regulating physiological systems, including the skeleto-muscular and locomotor system. Studies of cortico-muscular coordination have primarily focused on associations between movement tasks dynamics specific waves. However, brain-muscle functional networks synchronous among waves muscle activity rhythms that underlie control remain unknown. Here we address following fundamental questions: what are structure networks; whether main network mediators control; how...
To compare the efficacy of subcutaneous foslevodopa/foscarbidopa (LDP/CDP) with oral levodopa/carbidopa (LD/CD) across prespecified subgroups patients advanced Parkinson's disease (PD) in a phase 3 study.
Patients with postural orthostatic tachycardia syndrome (POTS) present to outpatient dysautonomia clinics endorsing a wide range of symptoms. Dry eyes and mouth, or sicca complex are frequently reported. This retrospective study investigates the incidence quantifies severity dry eye (DES) in patients POTS.This compiles survey results, clinical data from twenty-three POTS (22 females, average age 34.9 st dev 14.0 years) surveyed during their initial follow-up appointments. Patient's...
SUMMARY Huntington's disease (HD) is an inherited, neurodegenerative disorder characterized by progressive motor dysfunction, abnormal involuntary movements, emotional disturbances and cognitive decline. There currently no treatment to modify the progression of HD. Until modifying agents are established, symptomatic remains cornerstone management. Treating chorea other symptoms may improve quality life sufferers. Multiple interventions have been studied for chorea, but tetrabenazine only US...
Visual hallucinations are reported in 16-37% of drug-treated patients with Parkinson's disease (PD) and the most common PD. We report two PD symptoms that uniquely integrate visual delusions. cases who saw persistence these photographs. These pictures were taken to prove absence hallucinations. believe this is first description peculiar phenomenon, which or illusions could be replicated Both had delusions associated images we speculate they photographs represent a further delusion, hence...
This project aimed to educate medical students on climate change and weather, focusing raising awareness about its potential impacts neurological disorders.
To investigate how positive redirection of dreams provided by the caregiver can help improve symptoms associated with rapid eye movement (REM) sleep behavior disorder.
Variants in the ryanodine receptor 2 (RYR2) gene are primarily associated with catecholaminergic polymorphic ventricular tachycardia. However, recent studies have also identified potential links to neurological pathologies, including Alzheimer’s disease, benign epilepsy of childhood, and neurodevelopmental disorders. Despite these findings, there is limited data on association between RYR2 variants additional symptoms, such as autonomic dysfunction. This case report describes...
OBJECTIVE: To characterize nocturnal awakenings in patients with Postural Orthostatic Tachycardia Syndrome (POTS).
May 6, 2019April 9, 2019Free AccessEffect of a faculty-led comprehensive mentorship program on medical student recruitment and research productivity in neurology (P2.9-038)Shuhan Zhu, Elie Sader, Natalie Thom, Okeanis Vaou, Anna HohlerAuthors Info & AffiliationsApril 2019 issue92 (15_supplement)https://doi.org/10.1212/WNL.92.15_supplement.P2.9-038 Letters to the Editor
OBJECTIVE: To identify the prevalence of alpha-delta sleep in Postural Orthostatic Tachycardia Syndrome (POTS) patients.