A5100632544- Metabolomics and Mass Spectrometry Studies
- Curcumin's Biomedical Applications
- Parkinson's Disease Mechanisms and Treatments
- Porphyrin Metabolism and Disorders
- Paraquat toxicity studies and treatments
- Diet and metabolism studies
- Mitochondrial Function and Pathology
- Adipose Tissue and Metabolism
- Genetics and Neurodevelopmental Disorders
- Receptor Mechanisms and Signaling
- Cancer, Hypoxia, and Metabolism
- Pancreatic function and diabetes
- Cassava research and cyanide
- Aldose Reductase and Taurine
- Pesticide Exposure and Toxicity
- Traditional Chinese Medicine Analysis
- Cardiac Ischemia and Reperfusion
- Protein Degradation and Inhibitors
- Pharmacological Effects of Natural Compounds
- Ginseng Biological Effects and Applications
- Nicotinic Acetylcholine Receptors Study
- Enzyme function and inhibition
- Metabolism and Genetic Disorders
- Ziziphus Jujuba Studies and Applications
- Phytochemicals and Antioxidant Activities
Third Affiliated Hospital of Guangzhou Medical University
2024
Guangzhou Medical University
2024
Ministry of Education of the People's Republic of China
2017-2021
Northwest University
2013-2021
Science North
2010
Although the adriamycin-induced nephropathy model is frequently employed in study of nephrotic syndrome and focal segmental glomerulosclerosis, accompanying myocardial damage has always been a cause for concern. Therefore, there great need to cardiorenal communication this model.An was established via tail vein injection. The levels biochemical indicators serum albumin, globulin, total protein, cholesterol, creatinine (SCr), urinary (UCr) were measured, histopathological changes heart...
Abstract A sensitive, specific and accurate liquid chromatography–tandem mass spectrometry (LC–MS/MS) method was developed validated for the simultaneous determination of seven constituents Zaoren Anshen prescription (ZAP) in rat plasma after oral administration ZAP: spinosin, salvianic acid A, 6′′′‐feruloylspinosin, protocatechualdehyde, salvianolic B, schisandrin deoxyschisandrin. The samples internal standard (IS) sulfamethoxazole were extracted using acetonitrile. Chromatographic...
Bornyl gallate (BG) is a potential drug candidate synthesized by the reaction of two natural products, gallic acid and borneol. Previous studies have strongly suggested that BG worthy further investigation due to antioxidant, antiatherosclerosis activities, obvious activity stimulating intersegmental vessel growth in zebrafish. This work was designed elucidate metabolic profile through analyzing its metabolites vitro vivo chromatographic separation coupled with mass spectrometry. The were...
Forced swimming in cold water causes physiological and psychological stress that leads to altered biochemical homeostasis neurobehavioral responses. In this study, plasma urinary metabolites Sprague-Dawley (SD) rats subjected forced (CWFSS) were characterized using NMR conjunction with multivariate data analysis. Metabolic analysis demonstrated decreased levels of lipoprotein increased O-acetyl glycoprotein, glucose, lactate, pyruvate, creatine, citrate, succinate amino acids including...
To study the influence of processing on metabolism main component bitter almond-amygdalin in rat.The blood was collected at different times after amygdalin given by injection and oral, almond its processed production oral respectively, then detected both HPLC HPLC-MS(n) methods extraction pretreatment.After injection, absorbed prototype to rapidly, while other three kinds medicine were all not amygdalin, but two metabolites which isomers prunasin confirmed mass spectrometry. The metabolic...
Background: Curcumin (CUR), a natural isolated compound from turmeric, helps in fighting many diseases, but the broad application of curcumin has been limited ascribed to low bioavailability. Objective: The aim this study is pursue enhancement bioavailability through coadministration vitamin C. Methods: Such purpose was achieved analysis pharmacokinetics by highperformance liquid chromatography coupled with electrospray ionization - tandem mass spectrometry (HPLC ESI MS/MS). plasma separated...