- Analytical Methods in Pharmaceuticals
- Analytical Chemistry and Chromatography
- Quinazolinone synthesis and applications
- Synthesis and Characterization of Heterocyclic Compounds
- Synthesis and biological activity
- Chemical Synthesis and Reactions
- Phenothiazines and Benzothiazines Synthesis and Activities
- Catalytic Cross-Coupling Reactions
- Synthesis and Biological Evaluation
- Multicomponent Synthesis of Heterocycles
- Catalytic C–H Functionalization Methods
- Chemical Synthesis and Analysis
- Synthesis of Organic Compounds
- Sulfur-Based Synthesis Techniques
- Structural Health Monitoring Techniques
- Reproductive Physiology in Livestock
- N-Heterocyclic Carbenes in Organic and Inorganic Chemistry
- Antibiotics Pharmacokinetics and Efficacy
- Advanced Sensor and Energy Harvesting Materials
- Synthesis of heterocyclic compounds
- Synthesis and Catalytic Reactions
- Thermodynamic and Exergetic Analyses of Power and Cooling Systems
- Oxidative Organic Chemistry Reactions
- Organic Chemistry Cycloaddition Reactions
- Catalytic Alkyne Reactions
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ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTModeling of naphtha pyrolysisPramod Kumar and Deepak KunzruCite this: Ind. Eng. Chem. Process Des. Dev. 1985, 24, 3, 774–782Publication Date (Print):July 1, 1985Publication History Published online1 May 2002Published inissue 1 July 1985https://pubs.acs.org/doi/10.1021/i200030a043https://doi.org/10.1021/i200030a043research-articleACS PublicationsRequest reuse permissionsArticle Views1412Altmetric-Citations107LEARN ABOUT THESE METRICSArticle Views...
Abstract Supersonic intakes, under adverse operating conditions, can have unwanted oscillations of shock system internal and external to its duct, known as intake buzz. These buzz instabilities degrade performance by causing violent pressure fluctuations, reducing mass flow, decreasing thrust, leading combustion well. This study examines the onset this in an axisymmetric with various throttles investigates effects dynamic angular deflection a portion cowl on resulting phenomena. Computations...
A four-stage manufacturing route for the preparation of dolutegravir sodium (1) was assessed and optimized leading to a higher yielding, simpler scalable process. Key improvements in process include development mild workup procedure by selective derivatization difficult remove impurity using tert-butyldimethylsilyl chloride. Metal-based hydrogenation-free O-debenzylation is optimized, critical isomeric formed identified eliminated from establishment proper control strategy.
A new industrial process, involving only two isolation and drying steps, for 10-methoxyiminostilbene (MISB), an advance intermediate of widely prescribed antiepileptic drug, oxcarbazepine, has been developed. salient feature this process is the novel use 1,3-dibromo-5,5-dimethylhydantoin (DBDMH) to afford bromohydrin methyl ether from N-acetyliminostilbene. The byproducts namely acetic acid, 5,5-dimethylhydantoin Et3N·HBr are recyclable as well nontoxic. This amenable large-scale production MISB.
One unknown impurity (Imp-II) during the analysis of laboratory batches isoproterenol hydrochloride was detected in level ranging from 0.04% to 0.12% by high performance liquid chromatography with UV detection. The structure proposed as 4-[2-(propan-2-ylamino)ethyl]benzene-1,2-diol using chromatography--mass spectrophotometry (LC--MS) analysis. Imp-II isolated semi-preparative impurity-enriched reaction crude sample. Its confirmed nuclear magnetic spectroscopy such 1H, 13C, DEPT (1D NMR),...