A5067106485- Aquaculture Nutrition and Growth
- Protein Hydrolysis and Bioactive Peptides
- Advanced Chemical Sensor Technologies
- Fish Biology and Ecology Studies
- Alcohol Consumption and Health Effects
- Vitamin C and Antioxidants Research
- Electrochemical sensors and biosensors
- Vitamin D Research Studies
- Salivary Gland Disorders and Functions
- Mitochondrial Function and Pathology
- Polyamine Metabolism and Applications
- Neonatal Health and Biochemistry
- Biotin and Related Studies
- Water Treatment and Disinfection
- Metabolism and Genetic Disorders
- Metabolomics and Mass Spectrometry Studies
- Diet and metabolism studies
- Meat and Animal Product Quality
- Forensic Toxicology and Drug Analysis
- Identification and Quantification in Food
Sinop University
2019
Hyperphenylalaninemia (HPA) is defined as blood phenylalanine (Phe) levels exceeding the normal values (>120 μmol/L or >2 mg/dL) and caused by a deficiency in enzyme hydroxylase (PAH). The widespread screening of Phe newborn programs has led to very high number patients with HPA.
Abstract This study presents a comparative analysis of non-enzymatic electrochemical voltammetric sensors, utilizing phenylalanine amino acid metal complexes (M: Ni, Zn, and Co) Polyaniline (PANI) nanocomposites (NCs). The PANI: Zn(Phala)₂ NCs-based sensor detected dopamine (DA) with sensitivity 101.18 μAμM−1 cm−2. limit detection (LOD) for the was calculated as 0.391 μM. exceptional makes highly promising potential integration into biomedical test kits. To gain deeper insights structural...
The rs7041 and rs4588 polymorphisms found in the GC gene, encoding vitamin D-binding protein (DBP), have distinct biochemical phenotypes. aim of this study was to investigate D parameters with these polymorphisms, individuals possible deficiency. most common (49% cohort) genotype GT, especially among high levels free 25(OH)D calculated but low bioavailable 25(OH)D, it AC particular 25(OH)D. phenotypes were Gc1s/2 (35.3%) Gc1s/1s (31.4%), Gc1f/1f rare (5.9%). variations healthy Turkish may be...
Bu çalışmada Karadeniz’de Sinop yarımadası civarında yakalanan izmarit balığı (Spicara smaris) etinin amino asit içeriği ve bu balığın boy ağırlık ilişkisi belirlenmiştir. Amino içeriğinin belirlenmesinde; bir karışımdaki istenen maddeyi ileri düzeyde ayırıp tanımlayabilir ölçebilir özellikteki LC-MS / MS (Sıvı Kromatografi Kütle Spektrometresi) cihazı kullanılmış yöntemle balıkları için sonuçlar ilk kez rapor edilmiştir. esansiyel (EAA) olmayan (NEAA) toplam 19 adet tespit Esansiyel asitler...
LC-MS/MS was used to determine the amino acid composition in muscle, ovary and liver of whiting, Merlangus merlangus euxinus, caught off coast Sinop province Black Sea. A total 19 acids (AA) were found different samples. The essential (EAA) tissues whiting 55.9% meat, 54.8% 51.7% acids. AA contents except for Arg, Glu, Pro Tau meat not significantly (P > 0.05), but Cys, Tyr, Asp, Orn these two < 0.05) higher than liver. These results showed that ovaries have approximately as...
Nitrosamines (NAs) are classified as probable or possible human carcinogens by the International Agency for Research on Cancer (IARC) and presence of these impurities has resulted in numerous drug recalls from market. In April 2020, ranitidine which is prescribed to reduce amount acid secreted stomach been recalled owing contamination with NAs. this work, a simple sensitive method simultaneous determination 10 NAs were developed, utilizing atmospheric pressure chemical ionisation source...
Bu çalışmada, Karadeniz’de Sinop kıyılarından avlanan hamsi balığı etinin esansiyel amino asit (EAA) ve olmayan (NEAA) profili, LC-MS/MS cihazıyla bu cihaza uygun olarak modifiye edilmiş yöntem ile ilk kez analiz edilmiştir. Sonuçlar daha önce diğer balıklar üzerine yapılmış çalışmalarla kıyaslanarak, içeriği balıklardan farkı tartışılmıştır. Hamsi etinde toplam 19 adet tespit olup arginine, cystine, histidine, isoleucine, leucine, lysine, methionine, phenylalanine, serine, threonine,...
Abstract Background Reliable biomarkers have great significance in the investigation of alcohol consumption patterns and treatment alcohol-induced diseases. Direct to detect intake are non-oxidative products ethanol metabolism (1, 2). Phosphatidylethanol (PEth), blood-based direct biomarker, represents a group unnatural phospholipids formed on leukocytes predominantly erythrocyte membranes. The presence PEth blood samples is an indisputable indicator (3, 4). Moreover, detecting drugs abuse...
ÖzAmaç: Etil glukuronit (EtG) ve etil sülfat (EtS), etanolün oksidatif olmayan minör metabolitleridir.İlk etanol tüketiminden kısa bir süre sonra çeşitli vücut sıvılarında tespit edilebilirler ana bileşik olan alkolden daha uzun dedeksiyon penceresine sahiptirler.Son alkol tüketimine yönelik oldukça hassas spesifik biyobelirteçler olarak kabul edilirler.EtG EtS biyobelirteçleri genellikle klinik adalet sistemi içinde uzaklaşmanın izlenmesinde kullanılmaktadır.Bu çalışmada, idrar serum...