In Bangladesh, an array of measures have been adopted to control the rapid spread COVID-19 epidemic. Such general population could significantly influence perception, knowledge, attitudes, and practices (KAP) towards COVID-19. Here, we assessed KAP immediately after lock-down were implemented during rise period outbreak. Online-based cross-sectional study conducted from March 29 April 19, 2020, involving Bangladeshi residents aged 12-64 years, recruited via social media. After consenting,...

ABSTRACTBACKGROUND: Latin American countries have been profoundly affected by COVID-19. Due to the alarming incidence of identified cases, we intended explore which psycho-social elements may be influencing poor adherence toward mandatory control measures among population. OBJECTIVE: We aimed assess knowledge, attitudes and vulnerability perception Peruvians during coronavirus outbreak.METHOD: Using a web-based cross-sectional survey, collected data from 225 self-selected participants,...

Life style conditions such as social relationships and diet impinge on mood homeostasis, a mechanism that becomes dysregulated in high-incidence mental illnesses depression or Alzheimer dementia (AD). Since insulin-like growth factor 1 (IGF-1) modulates its blood levels are altered both AD affective disorders, we investigated whether activity was the brain of mice submitted to isolation fed with high-fat (HFD). As humans, life increased anxiety depression-like behavior. Significantly,...

Theory of mind (ToM) is crucial for socioemotional interaction. ToM deficits may explain behavioral changes in dementia, especially Alzheimer's disease (AD) and frontotemporal dementia (FTD). This study examined the psychometrics a new test healthy adults, identified differences syndromes, assessed if scores predict neuropsychiatric function real-life behavior. The UCSF Cognitive Emotional Perspective Taking Test (CEPT) was evaluated 195 adults (age: 42.69 ± 16.20) clinic cohort 304...

In Bangladesh, an array of measures have been adopted to control the rapid spread COVID-19 epidemic. Such general population could significantly influence perception, knowledge, attitudes, and practices (KAP) towards COVID-19. Here, we assessed KAP immediately after lock-down were implemented during rise period outbreak. Online-based cross-sectional study conducted from March 29 April 19, 2020, involving Bangladeshi residents aged 12-64 years, recruited via social media. After consenting,...

Background: Latin American countries have been profoundly affected by COVID-19. Due to the alarming incidence of identified cases, we intended explore which psychosocial elements may influence poor adherence mandatory control measures among population. Objective: We aimed assess Peruvians’ knowledge, attitudes, and vulnerability perception during coronavirus outbreak. Method: collected data from 225 self-selected participants using a web-based cross-sectional survey. Results: The overall...

Insulin-like growth factor-I (IGF-I) signaling plays a key role in learning and memory processes. While the effects of IGF-I on neurons have been studied extensively, involvement astrocytes consequences synaptic plasticity animal behavior remain unknown. We found that induces long-term potentiation (LTP IGFI ) postsynaptic potentials is caused by depression inhibitory transmission mice. demonstrated this long-lasting decrease evoked astrocytic activation through its receptors (IGF-IRs). show...

Although sleep disturbances are common co-morbidities of metabolic diseases, the underlying processes linking both not yet fully defined. Changes in duration paralleled by changes levels insulin-like growth factor-I (IGF-I), an anabolic hormone that shows a circadian pattern circulation and activity-dependent entrance brain. However, specific role, if any, IGF-I this universal homeostatic process remains poorly understood. We now report activity orexin neurons, discrete cell population...

Increasing evidence supports the notion that Alzheimer's disease (AD), a condition presents heterogeneous pathological disturbances, is also associated to perturbed metabolic function affecting insulin and insulin-like growth factor I (IGF-I). While impaired activity leading resistance has been AD, whether altered IGF-I affects not entirely clear. Despite limitations of mouse models mimic AD pathology, we took advantage serum deficient mice (LID mice) present many functional perturbations in...

Even though infant crying is a common phenomenon in humans' early life, it still challenge for researchers to properly understand as reflection of complex neurophysiological functions. Our study aims determine the association between neonatal cry acoustics with signals and behavioral features according different distress levels newborns.Multimodal data from 25 healthy term newborns were collected simultaneously recording vocalizations, electroencephalography (EEG), near-infrared spectroscopy...

Obesity is a risk factor for Alzheimer’s disease (AD), but underlying mechanisms are not clear. We analyzed peripheral clearance of amyloid β (Aβ) in overweight mice because its systemic elimination may impact brain Aβ load, major landmark AD pathology. also whether circulating insulin-like growth I (IGF-I) intervenes the effects as this modulates and increased serum mice. Overweight showed accumulation by liver, site Aβ, unaltered levels. found that hepatocytes stimulated IGF-I, with low...

Abstract During the current pandemic, Pakistan is badly affected. It has exerted great pressure on vigor as well psychology of healthcare professionals. Limited resources, illiteracy, myths, and not following proper protocol by general population may have increased risk for everyone, anxiety fear among frontline Anxiety a common response to any stressful situation its unknown it multiple consequences.In study, we attempted analyze professionals Pakistan. An online questionnaire-based survey...

Abstract Maladaptive coping behaviors are probably involved in post-traumatic stress disorders (PTSD), but underlying mechanisms incompletely understood. We now report that mice lacking functional insulin-like growth factor I (IGF-I) receptors orexin neurons of the lateral hypothalamus (Firoc mice) unresponsive to anxiolytic actions IGF-I and develop PTSD-like behavior is ameliorated by inhibition neurons. Conversely, systemic treatment a wild-type mouse model PTSD (PTSD mice). Further,...

The coronavirus (COVID-19) pandemic, confinement, fear, lifestyle changes, and worldwide health care impacted almost all diseases. Reports from countries outside Latin America revealed differences in migraine patients. In this study, we describe compare the immediate changes symptoms associated with COVID-19 quarantine patients Argentina, Mexico, Peru. An online survey was conducted May to July 2020. answered by 243 patients, questions related sociodemographic data, conditions, working...

Electroencephalography (EEG) can detect changes in cerebral activity during spaceflight. This study evaluates the effect of spaceflight on brain networks through analysis Default Mode Network (DMN)'s alpha frequency band power and functional connectivity (FC), persistence these changes. Five astronauts' resting state EEGs under three conditions were analyzed (pre-flight, in-flight, post-flight). DMN's FC computed using eLORETA phase-locking value. Eyes-opened (EO) eyes-closed (EC)...

El objetivo de esta revisión bibliográfica es delimitar y conceptualizar la Teoría Mente (ToM), como un proceso carácter metacognitivo socioemocional que permite reconocer las intenciones, creencias emociones los otros, así propias, favoreciendo una efectiva interacción humana. Se analizan distintas teorías explicativas este concepto, especialmente postura modular sus niveles complejidad, métodos evaluación relevancia en estudios actuales Latinoamérica sobre fenómenos conscientes psicopatología.

Anorexia nervosa (AN) is a very debilitating disorder and has shown different cognitive deficit patterns. Some of them are controversial because they relate some with autistic traits. Both, social cognition executive function top-down processes that regulate interaction adaptive behavior in complex world. Neurocognitive profiles focused on this process especially useful as endophenotypes clinic research intervention.The aims study (1) assessing the contribution to socio-emotional...

We recently reported that exercise increases resilience to stress in young female mice.Underlying mechanisms include an interaction of the ovarian hormone estradiol (E2) with insulin-like growth factor I (IGF-I), and increase hippocampal levels latter.Since changes mood regulation during aging may contribute increasing incidence affective disorders at older age, we determined whether protective actions are maintained later ages.We found peri-menopause, no longer improves even becomes...

Introduction. Social cognition (SC) and executive function (EF) research in borderline personality disorder (BPD) has proven to be controversial lack of sufficient information about deficit patterns. Objective. Assess the contribution SC EF socio-emotional cognitive patterns BPD, as well investigate possible relationships between SC, EF, clinic features BPD. Method. The study evaluated 20 females with BPD ambulatory hospitalization healthy women social (“Reading mind through eyes” IOWA...