A5107638198- Fungal Biology and Applications
- Silymarin and Mushroom Poisoning
- Carcinogens and Genotoxicity Assessment
- Polyamine Metabolism and Applications
- Growth Hormone and Insulin-like Growth Factors
- Enzyme function and inhibition
- Hypothalamic control of reproductive hormones
- Synthesis and Biological Evaluation
- Syphilis Diagnosis and Treatment
- Medicinal plant effects and applications
- Stress Responses and Cortisol
- bioluminescence and chemiluminescence research
- Chemical Reactions and Isotopes
- Reproductive tract infections research
- Microbial infections and disease research
- Autoimmune Bullous Skin Diseases
- Phytochemistry and Bioactivity Studies
- Cancer Immunotherapy and Biomarkers
- Electron Spin Resonance Studies
- Amino Acid Enzymes and Metabolism
- Neuroendocrine regulation and behavior
- Cutaneous lymphoproliferative disorders research
- Regulation of Appetite and Obesity
- Cutaneous Melanoma Detection and Management
- CAR-T cell therapy research
Semmelweis University
2010-2023
The University of Texas Medical Branch at Galveston
2018
Hungarian Academy of Sciences
2001-2012
Ludwig-Maximilians-Universität München
2007-2008
München Klinik
2008
Klinik und Poliklinik für Frauenheilkunde und Geburtshilfe
2007-2008
Klinik für Frauenheilkunde
2007-2008
University of Nebraska Medical Center
1991-2006
The Eppley Laboratory (United States)
2006
Western New Mexico University
2004
Abstract Solutions of hydrazine as 0.001%, methylhydrazine 0.01%, sulfate and ammonium hydroxide 0.3, 0.2 0.1% were administered continuously in the drinking water 5‐ 6‐week‐old randomly bred Swiss mice for their entire lifetime. Similarly a solution was given to 7‐week‐old inbred C3H mice. Hydrazine significantly increased incidence lung tumors mice, while enhanced development this neoplasm by shortening its latent period. The treatments were, however, without carcinogenic effect, did not...
Administration of 0.01% unsymmet,rical 1,1-dimethylhydrazine in the drinking water 5-week-old randombred Swiss mice throughout their lifetime induced tumors blood vessels, lung, kidney, and liver. The incidences these 4 tissues were: 79, 71, 10, 6%, while untreated controls they were 2, 11, 0, 0%, respectively. vascular occurred liver, muscle, heart, fat. Macroscopic, light electron microscopic, histochemical examinations lesions revealed a morphology typical angiosarcomas. gross histologic...
Abstract The isolation and identification of a prolactin‐releasing factor (PRF) from the neuro‐intermediate lobe pituitary gland has been pursued for over decade. Using high‐pressure liquid chromatography with electrochemical detection (HPLC‐ECD) gas chromatography/mass spectrometry (GC/MS) (R)‐salsolinol (SAL) (a dopamine‐related stereo‐specific tetrahydroisoquinoline) was found to be present in as well median eminence extracts male, intact‐, ovariectomized female rats. Moreover, analysis...
In Swiss mice receiving a single subcutaneous injection of 7,12-dimethylbenz[α]anthracene (DMBA) at birth there is dose level which the carcinogen induces high incidence malignant lymphomas. Increasing above this shortens latent period. Newborn animals are more susceptible to leukemogenic effect DMBA than 2 4 weeks old. The lymphomas observed under our experimental conditions were either undifferentiated (stem cell) type or showed varying types differentiation that lymphocytic, histiocytic,...
4‐Methylphenylhydrazine hydrochloride (4‐MPH) was administered to randomly bred Swiss mice as 26 weekly sc infections of 140 μg per gram body weight and N'‐acetyl‐4‐(hydroxymethyl)phenylhydrazine (AMPH) injections 500 μg/g. As o solvent control, physiological saline also given 0.01 ml/g. The 4‐MPH treatment induced a significant incidence (24%) fibrosarcomas in males. In the 4‐MPH‐treated females some AMPH‐treated male mice, few soft‐tissue tumors were observed; however, their appearance...
Association between rectal or colon cancer risk and serine hydroxymethyltransferase 1 (SHMT1) C1420T methylenetetrahydrofolate reductase (MTHFR) C677T polymorphisms was assessed. The serum total homocysteine (HCY), marker of folate metabolism also investigated.The SHMT1 MTHFR genotypes were determined by real-time PCR PCR-RFLP, respectively in 476 patients with rectal, 479 461 478, respective controls matched for age sex. Homocysteine levels HPLC kit. association evaluated logistic...
A cell-free filtrate was prepared by the Gross technique from a thymic tumor induced single subcutaneous injection of 100 μg DMBA in Swiss mouse and diagnosed cytologically as malignant lymphoma, stem cell type. Out 7 survivors injected with at birth, 6 developed lymphomas, while no such occurred 10 mice treated similarly age 8 weeks. Cytologically they represented more differentiated namely lymphocytic type 5 cases one instance histiocytic
The presence of prolactin (PRL) mRNA in the mammary gland, placenta, and pituitary gland lactating pregnant rats was investigated by polymerase chain reaction (PCR). Polyadenylated RNA prepared from total samples oligo(dT)-cellulose chromatography, complementary cDNAs were synthesized. A standardized amount cDNA each sample used as template a Taq PCR under high-stringency conditions. amplified signal with predicted size approximately 375 bp glands rats, placentae rats. This band specifically...
Journal Article Tumors Induced in Mice by N-Methyl-N-formylhydrazine of the False Morel Gyromitra esculenta Get access Bela Toth, Toth 2The Eppley Institute for Research Cancer, University Nebraska Medical Center, 42d St. and Dewey Ave., Omaha, Nebr. 68105. Search other works this author on: Oxford Academic PubMed Google Scholar Donald Nagel 3We thank Dr. Kashinath Patil statistical analysis Mrs. Connie Anderson technical assistance. JNCI: National Cancer Institute, Volume 60, Issue 1,...