A5021549605- Obstructive Sleep Apnea Research
- Neuroscience of respiration and sleep
- Cardiovascular and Diving-Related Complications
- Sleep and Wakefulness Research
- Cardiovascular Disease and Adiposity
- Sleep and related disorders
- Restless Legs Syndrome Research
- Cardiovascular Health and Disease Prevention
- Diversity and Career in Medicine
- Tracheal and airway disorders
- Respiratory Support and Mechanisms
- Blood Pressure and Hypertension Studies
- Circadian rhythm and melatonin
- Innovations in Medical Education
- Congenital Heart Disease Studies
- Heart Rate Variability and Autonomic Control
- Infection Control and Ventilation
- Biomedical Research and Pathophysiology
- Healthcare professionals’ stress and burnout
- Amyotrophic Lateral Sclerosis Research
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Dementia and Cognitive Impairment Research
- Hip disorders and treatments
- Myasthenia Gravis and Thymoma
- Travel-related health issues
University of Minnesota
2016-2025
University of Minnesota Medical Center
2018-2024
University of Minnesota System
2024
Vidyasagar University
2021
Fairview Health Services
2020
Pulmonary and Allergy Associates
2010-2015
Mayo Clinic
2006-2012
Mayo Clinic in Arizona
2007-2012
Mayo Clinic in Florida
2012
WinnMed
2006
The incidence of sleep-related breathing disorder (SRBD) remains unclear in patients with a continuous flow left ventricular assist device (LVAD). Polysomnography (PSG) the gold standard for diagnosis, but logistical challenges make home sleep apnea testing (HSAT) more practical alternative. WatchPat has failed to accurately diagnose SRBD this population. In contrast, NOX-T3 utilizes channels monitor physiological variables potentially offering improved diagnostic accuracy. Therefore, we...
The link between obesity, hyperleptinemia, and development of cardiovascular disease is not completely understood. Increases in leptin have been shown to impair signaling via caveolin-1-dependent mechanisms. However, the role hyperleptinemia versus impaired adipose tissue known.To determine presence significance leptin-dependent increases caveolin-1 expression humans.We designed a longitudinal study investigate effects on during weight gain humans. Ten volunteers underwent 8 weeks...
Obesity has been associated with increased cardiac sympathetic activation during wakefulness, but the effect on sleep-related modulation is not known. The aim of this study was to investigate fat gain autonomic control wakefulness and sleep in humans. We performed a randomized, controlled assess effects heart rate variability. recruited 36 healthy volunteers, who were randomized either standardized diet ≈4 kg over 8 weeks followed by an 8-week weight loss period (n=20) or serve as...
Sleep medications may contribute to dementia development or indicate sleep disturbances that are markers of contributors neurologic disease. The objective this study was examine the use and incident in a community-based cohort older adults. We hypothesize late-life medication is associated with greater risk dementia.
Scientific investigations in the past few decades have supported important role of sleep various domains health. Sleep apnea is a highly prevalent yet underdiagnosed disorder representing valid cardiovascular risk factor, particularly for hypertension. While several studies demonstrated benefits treatment on subclinical measures, there paucity proving reduction events and mortality. Sufficient high-quality also maintenance Future should focus improving identification patients at greatest...
Introduction:The development of repetitive central apneas during application CPAP in patients initially showing obstructive apneas, a condition called complex sleep apnea syndrome (CompSAS), implies respiratory control instability.Respiratory is known to be transiently destabilized by arousals.We hypothesized that PLMS and PLMrelated arousals would more frequent with CompSAS compared those (OSA) could account for some the instability.Methodology: Comparative retrospective review studied our...
Asian Indians have markedly increased mortality due to coronary artery disease (CAD). Impaired endothelial function has been linked an risk of acute cardiovascular events. We tested the hypothesis that was attenuated in and Caucasians.We studied 14 [mean age: 30 ± 6 years; mean body mass index (BMI): 25 3 kg/m(2)] 11 Caucasians (mean 5 BMI: 26 2 kg/m(2)). All subjects were healthy men nonsmokers without any history CAD or diabetes not taking medications. Endothelial evaluated by ultrasound...
The aim of this study was to utilize an intersectional framework examine academic faculty's lived experiences during COVID-19. Specifically, we set out to: (1) describe the multiple identities (
Many medical schools are instituting gender equity initiatives to address long-standing inequities (e.g., salary, leadership positions, resource distribution) between women and men in academic medicine. However, few theory-driven models exist with built-in metrics assess the impact of initiatives. The authors describe theory- metric-driven process used create Center for Women Medicine Science (CWIMS) at University Minnesota (UMN) Medical School. An innovative approach using community-based...
From the age of menarche through menopause, women report insufficient sleep and insomnia more frequently than men similar ages. The physiological hormonal changes that occur during puberty, menstrual cycle, pregnancy, perimenopause, menopause all influence women’s architecture quality. prevalence some disorders, such as insomnia, hypersomnia, restless legs syndrome are higher in compared with men. other obstructive apnea parasomnias, increase specific stages life. At same time, there a few...
Abstract Introduction Some OSA patients have sleep associated hypoxemia, defined as time spent with oxygen (O2) saturation ◻88% for > 5 minutes (T88). Positive airway pressure (PAP) is the gold standard treatment OSA. Apnea-Hypopnea index (AHI) estimation from PAP download (DL) used by clinicians to determine efficacy. Overnight oximetry therapy usually check resolution of hypoxemia. During COVID-19 pandemic, we WPAT hypoxemia in who were prescribed therapy. However, this practice...