- Intracranial Aneurysms: Treatment and Complications
- Cerebrovascular and Carotid Artery Diseases
- Acute Ischemic Stroke Management
- Moyamoya disease diagnosis and treatment
- Advanced MRI Techniques and Applications
- Traumatic Brain Injury and Neurovascular Disturbances
- Glioma Diagnosis and Treatment
- Cardiovascular Health and Disease Prevention
- Meningioma and schwannoma management
- Neurological Complications and Syndromes
- Medical Imaging Techniques and Applications
- Neurofibromatosis and Schwannoma Cases
- Craniofacial Disorders and Treatments
- Cardiac and Coronary Surgery Techniques
- Neurosurgical Procedures and Complications
- Vascular Malformations Diagnosis and Treatment
- Head and Neck Surgical Oncology
- Cerebrospinal fluid and hydrocephalus
- Anesthesia and Neurotoxicity Research
- Spinal Fractures and Fixation Techniques
- Surgical Simulation and Training
- Spinal Dysraphism and Malformations
- Aortic Disease and Treatment Approaches
- Musculoskeletal pain and rehabilitation
- Dupuytren's Contracture and Treatments
Nagaoka University of Technology
2024
Kanagawa Cardiovascular and Respiratory Center
2019-2023
Kitasato University
2015-2022
Yokohama City University
2022
Chubu National Hospital
2017
Iwate Medical University
2008-2012
Cyclotron (Netherlands)
2011
Rabin Medical Center
2011
Adverse effects of intravenous acetazolamide administration for evaluation cerebrovascular reactivity using brain perfusion single-photon emission computed tomography (SPECT) were prospectively investigated in 100 patients with major cerebral artery, atherosclerotic, and steno-occlusive diseases. All underwent two SPECT studies (with without challenge) at an interval 2 or 3 days, received a questionnaire immediately after each study, returned the answered within 7 days study. None studied...
Cerebral hyperperfusion after carotid endarterectomy (CEA), even when asymptomatic, often impairs cognitive function. However, conventional magnetic resonance (MR) imaging rarely demonstrates structural brain damage associated with postoperative impairment. MR diffusion tensor (DTI) is potentially more sensitive for detection of white matter damage. Among the common parameters derived by DTI, fractional anisotropy (FA) a marker tract integrity, and mechanical disruption axonal cylinders loss...
Cerebral hyperperfusion after carotid endarterectomy (CEA) occurs in patients with preoperative impairments cerebral hemodynamics. Signal intensity of the middle artery (MCA) on single-slab 3-dimensional time-of-flight magnetic resonance angiography (MRA) can assess hemodynamic impairment hemisphere. The purpose present study was to determine whether signal MCA MRA could identify at risk for CEA.The ipsilateral CEA graded according ability visualize 81 internal stenosis (>or=70%). blood flow...
Low blood flow velocity in the middle cerebral artery (MCA) correlates with development of postoperative ischemic lesions related to generation microemboli during dissection carotid arteries endarterectomy (CEA).The purpose this prospectively controlled trial was determine whether increased mean MCA by intentional hypertension CEA prevented new caused intraoperative microemboli.Patients ipsilateral internal stenosis (>70%) underwent under transcranial Doppler monitoring and microembolic...
The purpose of the present study was to determine whether preoperative cerebral blood flow (CBF) or cortical central benzodiazepine receptor binding potential as measured by brain perfusion (123)I-iomazenil (IMZ) single-photon emission computed tomography (SPECT) imaging, respectively, can predict cognitive improvement after uncomplicated carotid endarterectomy (CEA).Neuropsychological testing performed preoperatively and 1 month postoperatively in 140 patients who underwent CEA for...
Oxygen extraction fraction (OEF) is a key predictor of stroke recurrence in patients with symptomatic major cerebral arterial occlusive disease. The purpose the present study was to compare central benzodiazepine receptor binding potential (BRBP) and blood flow (CBF) images on SPECT OEF PET chronic unilateral middle artery (MCA) or internal carotid (ICA) disease.OEF, CBF, BRBP were assessed using (15)O N-isopropyl-p-(123)I-iodoamphetamine (123)I-iomazenil SPECT, respectively, 20 healthy...
Objective The aim of the present study was to determine whether early and late/early images on 123I-iomazenil (IMZ) single-photon emission computed tomography (SPECT) correlate with cerebral blood flow (CBF) oxygen extraction fraction (OEF) PET, respectively, in cortex patients chronic unilateral middle artery or internal carotid occlusive disease. Methods In 20 normal individuals 68 patients, CBF OEF were assessed using 15O-PET, brain SPECT scans initiated immediately after (early images)...
Cerebral hyperperfusion syndrome is a potential complication of superficial temporal artery-MCA anastomosis for Moyamoya disease. In this study, we evaluated whether TOF-MRA could assess cerebral after disease.This retrospective study included patients with disease who underwent single anastomosis. and SPECT were performed before 1-6 days Bilateral ROIs on the source image manually placed directly parietal branch artery just branching frontal contralateral same axial image, respectively. The...
The aim of the present study was to determine whether central benzodiazepine receptor binding potential (BRBP)/cerebral blood flow (CBF) or a combination CBF and cerebrovascular reactivity (CVR) acetazolamide on single-photon emission computed tomography (SPECT) more accurately detects misery perfusion, indicating elevation absolute value oxygen extraction fraction (OEF) positron (PET), in patients with unilateral major cerebral artery occlusive diseases.In 84 patients, OEF, CBF, CVR...
Risk factors for cerebrovascular complications developing during or after carotid endarterectomy (CEA) include preoperative impairments in cerebral hemodynamics, as detected by the demonstration of decreased reactivity (CVR) to acetazolamide on brain perfusion SPECT. Central benzodiazepine receptor binding potential (CBRBP) and blood flow (CBF) images SPECT provide high sensitivity specificity detecting misery patients with chronic unilateral major artery occlusive disease. The aim present...
Mouthwashes play a pivotal role in oral care, and their efficacy has been explored extensively across various dimensions. As contribution to the development of novel care products, this study aims investigate psychophysiological effects aromatic mouthwashes during resilience period from short-term cognitive stressor utilizing biological signals subjective evaluations.
A 53-year-old man presented with subarachnoid hemorrhage (SAH) in the left sylvian fissure. Preoperative computed tomography angiography revealed symmetrical aneurysms located at bifurcations of right and middle cerebral arteries (MCAs). The MCA aneurysm responsible for SAH was clipped. patient received post-surgical volume expansion treatment that did not induce hypertension. His systolic blood pressure ranged from 170 to 225 mmHg between day first surgery 11th postoperative day. course...
A 48-year-old woman presented with a left cerebellopontine angle mass. Over 93-month period, the patient underwent seven surgeries, two radiosurgeries, and one external beam radiotherapy. The tumor was histologically benign at first operation, but exhibited unusually aggressive behavior after failed radiosurgery demonstrated clinical characteristics of malignancy such as spinal metastasis. gamma knife (GKR) for recurrence despite being located in resectable region. did not respond. Six...
A reduction in cortical benzodiazepine receptor binding potential on late images of I-123 iomazenil SPECT indicates irreversible neural damage or loss. We present the case a 26-year-old woman with status epilepticus whom imaging using and N-isopropyl-p-iodoamphetamine 7 9 days after last seizure, respectively, demonstrated central hyperperfusion affected cerebral hemisphere crossed cerebellar hypoperfusion. However, 3 months later, repeat studies showed resolution potential, hyperperfusion,
While the combination of an angiotensin receptor blocker with thiazide diuretics produces a clinically beneficial reduction in blood pressure patients who otherwise only partially respond to monotherapy blocker, pressure-lowering therapy antihypertensive drug regimens cerebral hemodynamic impairment may adversely affect hemodynamics. The purpose present exploratory study was determine whether losartan plus hydrochlorothiazide (LPH) worsens brain perfusion both hypertension and due...
Handling surgical microscopes with one hand requires force, especially when gripping the operating handle (OH) to swing optic axis toward surgeon and moving it laterally or medially. These physical issues may be attributable non-ergonomic handling of OH. To optimize ease OH handling, we applied ergonomic criteria positioning OH, i.e. holding at as little ulnar deviation possible abduction strengthen grip arm rotation. Of eight male surgeons a mechanically counterbalanced microscope, OPMI...
Knowledge of branching patterns external carotid artery (ECA) is essential for planning and execution head neck surgeries. Digital subtraction angiography (DSA) images 532 ECAs from 302 consecutive patients were retrospectively evaluated. We classify the branch variants ECA into three types, simply based on number branches arising close together. Type A, B, C are defined as two, three, four or more at a common point proximal ECA, respectively. In this classification, distal was counted one...
Posterior reversible encephalopathy syndrome (PRES) is rarely associated with subarachnoid haemorrhage (SAH). We present a case involving patient who developed PRES, prior to induction of hypertensive therapy, 2 days after the onset SAH due ruptured intracranial aneurysm.
Although the abnormal venous drainage into superior ophthalmic vein (SOV) is a well-known entity responsible for ocular symptoms, it remains unclear to what degree affects visual function. The purpose of this study was evaluate incidence, characteristics and outcomes disorders in patients with intracranial arteriovenous fistula (AVF) SOV.This retrospective involved eight diagnosed AVFs SOV between January 2014 December 2016.The most common location AVF cavernous sinus (CS) five patients,...