Xiaohe Chen

ORCID: 0000-0003-0508-5392
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About
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Research Areas
  • Liver physiology and pathology
  • Melanoma and MAPK Pathways
  • Synthesis and biological activity
  • Bone and Dental Protein Studies
  • Integrated Circuits and Semiconductor Failure Analysis
  • RNA and protein synthesis mechanisms
  • Periodontal Regeneration and Treatments
  • Connective Tissue Growth Factor Research
  • Animal Genetics and Reproduction
  • Silicon and Solar Cell Technologies
  • Bone Metabolism and Diseases
  • Cancer Mechanisms and Therapy
  • Mechanisms of cancer metastasis
  • Electrostatic Discharge in Electronics

China University of Petroleum, Beijing
2025

To explore the possibility of separating and establishing clonal cell subpopulations with different metastatic phenotype from a human lung large carcinoma line (WCQH-9801), to identify difference biological molecular biology between NL9980 L9981 lines.Two sub-cell lines (NL9980 L9981) were isolated established (WCQH-9801) by single cloning techniques. The RELP, mRNA protein transcript expression detected in Southern blot, RT-PCR Western blot. characteristics vivo vitro determined MTT, plate,...

10.3779/j.issn.1009-3419.2003.06.13 article EN Zhongguo feiai zazhi/Zhongguo fei'ai zazhi 2003-12-20

It has been known that oncogenesis and development of lung can- cer is a complex process regulated many genes involved in multistages. Recent studies have demonstrated signal transduction abnormality may play very important role these procedures. The aim this study to investigate the influence exogenous MEK1/2 pathway inhibitor U0126 on expression activity extracellular signal-regulated kinase (ERK1/2) human high-metastatic large cell cancer line L9981 its malignant biological behaviors.The...

10.3779/j.issn.1009-3419.2005.06.04 article EN Zhongguo feiai zazhi/Zhongguo fei'ai zazhi 2005-12-20
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