A5085926829- Advanced Fiber Laser Technologies
- Photoreceptor and optogenetics research
- Laser-Matter Interactions and Applications
- Nonlinear Optical Materials Studies
- Spectroscopy and Laser Applications
- Spectroscopy and Quantum Chemical Studies
- Luminescence Properties of Advanced Materials
- Nanoplatforms for cancer theranostics
- Retinal Development and Disorders
- Synthesis and properties of polymers
- Atomic and Subatomic Physics Research
- Quantum Information and Cryptography
- Advanced Fluorescence Microscopy Techniques
- Analytical chemistry methods development
- Spectroscopy Techniques in Biomedical and Chemical Research
- Nonlinear Dynamics and Pattern Formation
- Gold and Silver Nanoparticles Synthesis and Applications
- Air Quality Monitoring and Forecasting
- Photochromic and Fluorescence Chemistry
- Photorefractive and Nonlinear Optics
- Luminescence and Fluorescent Materials
- Advanced Chemical Sensor Technologies
- Advanced Chemical Physics Studies
- Neurobiology and Insect Physiology Research
- Pharmaceutical and Antibiotic Environmental Impacts
University of Geneva
2016-2024
University of Zurich
2017-2018
École Polytechnique Fédérale de Lausanne
2017-2018
University of Basel
2017-2018
Abstract Proton transfer is one of the most fundamental events in aqueous-phase chemistry and an emblematic case coupled ultrafast electronic structural dynamics 1,2 . Disentangling nuclear on femtosecond timescales remains a formidable challenge, especially liquid phase, natural environment biochemical processes. Here we exploit unique features table-top water-window X-ray absorption spectroscopy 3–6 to reveal proton-transfer ionized urea dimers aqueous solution. Harnessing element...
We experimentally study entangled two-photon absorption in rhodamine 6G as a function of the spatial properties high flux broadband photon pairs. first demonstrate key signature dependence rate on type pair attenuation: linear, when laser pump power is attenuated, and quadratic, itself experiences linear loss. then perform fluorescence-based Z-scan measurement to influence beam waist size process compare this classical single- processes. that shares similar absorption. This result presents...
The design of stimuli-responsive nanocarriers has raised much attention to achieve higher local concentration therapeutics and mitigate the appearance drug resistance. combination imaging properties controlled photorelease active molecules within same nanoconjugate a great potential for theranostic applications. In this study, system NIR light-triggered release molecular cargos induced by second harmonic emission from bismuth ferrite nanoparticles (BFO HNPs) is presented. Silica-coated BFO...
Abstract While chemotherapy is one of the most used treatments in oncology, systemic administration chemotherapeutics generally results undesired damages to healthy tissues and cells, side effects such as severe nausea leukopenia, reduced efficacy due multidrug resistance poor target accessibility. The limitations conventional formulation have prompted development alternative nanomaterials‐based strategies achieve targeted stimuli sensitive payload delivery reach optimal local drug...
Whereas most of the reports on nonlinear properties micro- and nanostructures address generation distinct signals, such as second or third harmonic, here we demonstrate that novel dual output lasers recently developed for microscopy can readily increase accessible parameter space enable simultaneous excitation detection multiple emission orders several harmonics signals stemming from various sum difference frequency mixing processes. This rich response, which in our case features 10...
In recent years, quantum Fourier transform infrared (QFTIR) spectroscopy was proposed as an alternative to conventional in the mid-infrared region of spectrum. this way, harnessing induced coherence and spectral entanglement offers perspectives for practical organic gasses detection. Still, little research conducted order bring QFTIR spectrometers closer domestic or in-field usage. work, we first use such a spectrometer open-path detection multiple interfering ambient air. The accurate...
In recent years, quantum Fourier transform infrared (QFTIR) spectroscopy has emerged as an alternative to conventional absorption in the mid-infrared region of spectrum. By harnessing induced coherence and spectral correlations photon pairs a nonlinear Michelson interferometer, this technique offers promising potential for practical detection organic gases. However, little research was conducted bring QFTIR spectrometers closer domestic or in-field usage. work, we present first use...
Abstract The optical identification of bioaerosols in the atmosphere and its discrimination against combustion related particles is a major issue for real-time, field compatible instruments. In present paper, we show that by embedding advanced pump-probe depletion spectroscopy schemes portable instrument, it possible to discriminate amino acid containing airborne (bacteria, humic particles, etc.) from poly-cyclic aromatic hydrocarbon (Diesel droplets, soot, vehicle exhausts) with high...
Nanoparticle-based drug delivery systems have the potential for increasing efficiency of chemotherapeutics by enhancing accumulation at specific target sites, thereby reducing adverse side effects and mitigating patient acquired resistance. In particular, photo-responsive nanomaterials attracted much interest due to their ability release molecular cargos on demand upon light irradiation. some settings, they can also provide complementary information optical imaging (sub)cellular scale. We...
Vision in living mice is sensitive to femtosecond pulse shaping.
A Quantum FTIR spectrometer was used to detect, discriminate and track organic gases in ambient air with unprecedented sensitivity, leveraging spectral entanglement, induced coherence, long-path absorption, specific analysis techniques such as DOAS.
We experimentally investigate fluctuations in the spectrum of ultrashort laser pulses propagating air, close to critical power for filamentation. Increasing peak broadens while beam approaches filamentation regime. identify two regimes this transition: In center spectrum, output spectral intensity increases continuously. contrast, on edges transition implies a bimodal probability distribution function intermediate incident pulse energies, where high-intensity mode appears and grows at...
Palcewska et al. first demonstrated near infrared (NIR) visual response in human volunteers upon two-photon absorption (TPA), a seminal work of 2014, and assessed the process terms wavelength- power-dependence on murine ex-vivo retinas. In present study, electroretinography (ERG) is further developed to perform complete characterization effect NIR pulse duration, energy, focal spot size response. The same set measurements successively tested living mice. We discuss how nonlinear intensity...
We experimentally investigate fluctuations in the spectrum of ultrashort laser pulses propagating air, close to critical power for filamentation. Increasing peak broadens while beam approaches filamentation regime. identify two regimes this transition: In center spectrum, output spectral intensity increases continuously. contrast, on edges transition implies a bimodal probability distribution function intermediate incident pulse energies, where high-intensity mode appears and grows at...
Whereas most of the reports on nonlinear properties micro- and nanostructures address generation distinct signals, such as second or third harmonic, we recently demonstrated that novel dual output lasers developed for microscopy can readily increase accessible parameter space enable simultaneous excitation detection multiple emission orders several harmonics signals stemming from various sum difference frequency mixing processes. [1] This rich response, which in our case features 10...