A5008494553- Genetics and Physical Performance
- Cardiovascular Effects of Exercise
- Muscle metabolism and nutrition
- Sports Performance and Training
- Adipose Tissue and Metabolism
- Renin-Angiotensin System Studies
- Muscle Physiology and Disorders
- Protein Degradation and Inhibitors
- Innovations in Medical Education
- Human Health and Disease
- Healthcare Systems and Public Health
- Diet and metabolism studies
- Eicosanoids and Hypertension Pharmacology
- Histone Deacetylase Inhibitors Research
- Sexual Differentiation and Disorders
- Medical Education and Admissions
- Sports Analytics and Performance
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Health and Medical Research Impacts
- Cardiovascular and exercise physiology
- Cardiovascular Disease and Adiposity
- GDF15 and Related Biomarkers
- Leadership and Management in Organizations
- Hormonal and reproductive studies
- Nutrition, Genetics, and Disease
St Petersburg University
2016-2024
Federal Scientific Center of Physical Culture and Sports
2006-2021
To date, studies investigating the association between ACTN3 R577X and ACE I/D gene variants elite sprint/power performance have been limited by small cohorts from mixed sport disciplines, without quantitative measures of performance. Aim: examine these sprint time in athletes. We collected a total 555 best personal 100-, 200-, 400-m times 346 sprinters large cohort Caucasian or African origin 10 different countries. Sprinters were genotyped for ID variants. On average, male with 577RR DD...
The functional 577R allele of the alpha-actinin-3 (ACTN3) gene has been reported to be associated with elite power athlete status, while nonfunctional 577XX genotype (predicts an deficient phenotype) hypothesised as providing some sort advantage for endurance athletes. In present study, distribution ACTN3 genotypes and alleles in Russian endurance-oriented athletes were examined association between competition results rowers sought.456 regional or national competitive standard involved...
Studies investigating associations between ACTN3 R577X and ACE I/D genotypes endurance athletic status have been limited by small sample sizes from mixed sport disciplines lack quantitative measures of performance. Aim: To examine the association best personal running times in a large homogeneous cohort runners. We collected total 1064 1500, 3000, 5000 m marathon 698 male female Caucasian athletes six countries (Australia, Greece, Italy, Poland, Russia UK). Athletes were genotyped for ID...
The performance of professional strength and power athletes is influenced, at least partly, by genetic components. main aim this study was to investigate individually in combination the association ACE (I/D), ACTN3 (R577X) PPARGC1A (Gly482Ser) gene polymorphisms with strength/power-oriented athletes' status two cohorts European athletes. A cohort Caucasians from Russia Lithuania (161 athletes: groups - weightlifters (87), powerlifters (60), throwers (14); elite 'elite' (104), 'sub-elite'...
Research concerned with predictors of talent in football has highlighted a number potentially important and partially inherited measures such as body size, anaerobic power, aerobic capacity, agility, psychological profile, game intelligence susceptibility to injuries. Genotyping for performance-associated DNA polymorphisms at an early age could be useful predicting later success football. The aim the study was investigate individually combination association common gene player's status. A...
The aim of the study was to determine association between ACE I/D, ACTN3 R577X and PPARA intron 7 G/C gene polymorphisms strength-related traits in 457 middle school-age children (219 boys 238 girls; aged 11 ± 0.4 years). assessment different phenotypes conducted with a number performance tests. Gene were determined by PCR. D allele associated high results standing long-jump test [II 148.3 (16.3) cm, ID 152.6 (19.6) DD 158.2 (19.1) cm; P = 0.037]. R tests males only combination other genes...
Muscle fibre type is a heritable trait and can partly predict athletic success. It has been proposed that polymorphisms of genes involved in the regulation muscle characteristics may predispose precursor cells given individual to be predominantly fast or slow. In present study, we examined association between 15 candidate gene composition vastus lateralis 55 physically active, healthy men. We found rs11091046 C allele carriers angiotensin II 2 receptor (AGTR2; skeletal development,...
Previous studies concerning the relevance of BDKRB2 gene polymorphisms revealed that absence (-9 allele) a nine-base-pair sequence in exon 1 is correlated with higher skeletal muscle metabolic efficiency glucose uptake during exercise, and endurance athletic performance. The aim study was to investigate association between -9/ 9 polymorphism elite status two cohorts eastern European athletes. We examined genotype distribution 9/ polymorphic site group Polish athletes confirmed results...
The androgen receptor (AR) gene contains a polymorphic trinucleotide (CAG) microsatellite repeat sequence (short or long alleles) that has been associated with fat-free mass in untrained men, which needs to be replicated athletic cohorts.The purpose of this study was explore the AR (CAG)n polymorphism trained individuals.A total 61 professional bodybuilders (40 males, 21 females), 73 elite male sprinters and weightlifters 186 controls were enrolled study. influence on muscle strength...
Previous studies concerning the relevance of BDKRB2 gene polymorphisms revealed that absence (−9 allele) a nine-base-pair sequence in exon 1 is correlated with higher skeletal muscle metabolic efficiency, glucose uptake during exercise, and endurance athletic performance. The aim study was to investigate association between −9/+9 polymorphism elite status two cohorts eastern European athletes. We examined genotype distribution 9/+9 polymorphic site group Polish athletes confirmed results...
The leading cause of death in the modern world is chronic non-infectious diseases, and metabolic risk factor high blood pressure. At present, role reactive oxygen species development arterial hypertension well known, influence epigenetic factors, such as social environment, daily routine, nutrition, combination with genetic predisposition, an important area study also. aim our was to identify frequency occurrence polymorphic variants marker gene angiotensinogen (rs4762) polymorphisms genes...
BACKGROUND: Cardiovascular disease remains a major public health problem associated with high mortality. The development of these diseases is many genetic and cardiovascular risk factors, so the study person’s predisposition to based on gene polymorphism actual. aim research was combination polymorphisms ADRB1 rs1801253, AGT rs4762, SOD2 rs4880 CAT rs1001179 genes in healthy young people assess individual disease.
 MATERIALS AND METHODS: involved 33 aged 19 21 years who currently had no...