A5008302042- Thyroid Cancer Diagnosis and Treatment
- Thyroid Disorders and Treatments
- Pituitary Gland Disorders and Treatments
- Hormonal Regulation and Hypertension
- Adrenal and Paraganglionic Tumors
- Ovarian function and disorders
- Growth Hormone and Insulin-like Growth Factors
- Head and Neck Anomalies
- Adipokines, Inflammation, and Metabolic Diseases
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Neuroendocrine Tumor Research Advances
- Adipose Tissue and Metabolism
- Diet and metabolism studies
- Cancer, Hypoxia, and Metabolism
- Diabetes and associated disorders
- Diabetes Management and Research
- Bariatric Surgery and Outcomes
- Pancreatic function and diabetes
- Thyroid and Parathyroid Surgery
- Adrenal Hormones and Disorders
- Sexual Differentiation and Disorders
- Reproductive Biology and Fertility
- Pharmacology and Obesity Treatment
- Hormonal and reproductive studies
- Nutritional Studies and Diet
Ege University
2015-2024
Izmir University
1999-2022
Ege Üniversitesi Tıp Fakültesi Hastanesi
2008-2017
Gazi University
2013
Endocrinology Research Center
2007
Ankara University
2000
University Medical Center
1998
Several health-promoting effects of kefir have been suggested, however, there is limited evidence for its potential effect on gut microbiota in metabolic syndrome This study aimed to investigate the regular consumption composition, and their relation with components syndrome. In a parallel-group, randomized, controlled clinical trial setting, patients were randomized receive 180 mL/day (n = 12) or unfermented milk 10) 12 weeks. Anthropometrical measurements, blood samples, pressure fecal...
The aims of the study were to identify medullary thyroid cancer (MTC) in its earliest stages by screening patients with basal calcitonin measurements and determine whether serum should be a part routine evaluation nodular goiter. Basal levels obtained from 75 (female:male 57:18, mean age 42.8 years, range 18-76 years) nonnodular disease as controls. Their level was 7.8+/-0.4 pg/mL 5-27 pg/mL. Seven hundred seventy-three goiter included 586:187) 46.1 years (range 17-78). Four had elevated...
We hypothesized that the administration of rosiglitazone, an insulin-sensitizing agent thiazolidinedione class, would improve ovulatory dysfunction, hirsutism, hyperandrogenemia, and hyperinsulinemia polycystic ovary syndrome (PCOS) patients. Forty women with PCOS impaired glucose tolerance test (IGT) were randomly assigned to 8-month treatment rosiglitazone at either 2 mg/day or 4 mg/day. compared changes in function, hormonal levels (total free testosterone, estradiol, estrone,...
The purpose of this study was to determine whether polycystic ovary syndrome (PCOS) and nonclassic 21-hydroxylase deficiency (CAH) are related hyperhomocysteinemia, investigate if there is a correlation between homocysteine levels insulin sensitivity in women with PCOS CAH. Fifty patients PCOS, 50 CAH 25 control were included the study. Blood samplings performed early follicular phase for measuring hormone profile, Vitamin B(12), folate, fasting blood glucose. Ovulatory status assessed timed...
Platelet dysfunction and its association with insulin resistance and/or hyperandrogenemia were evaluated in 50 women polycystic ovary syndrome (PCOS), non-classic congenital adrenal hyperplasia (NC-CAH), 30 the control group. Agonist-induced platelet aggregation was measured. Women PCOS had significantly higher levels of aggregations induced by ADP (77.4 +/- 3.3 vs. 67.3 2.8), collagen (79.7 1.8 69.1 3.9), epinephrine (84.7 2.6 67.8 3.8), compared controls. However NC-CAH because (68.2...
Interleukin (IL)-10 is a major anti-inflammatory cytokine that plays crucial role in the regulation of immune system. IL-10 has met criteria for an and immunosuppressive cytokine, its activity may be important clinical outcome diabetic nephropathy (DN). We aimed at evaluating relation between genotypic allelic frequencies (-1082G/A) polymorphisms, their association with risk to develop DN Turkish population.The genotypes were retrospectively determined 43 patients 48 without control group...
Purpose In this study, we aimed to assess the effectiveness of malignancy stratification algorithms American College Radiology (ACR) and European Thyroid Association (ETA) in delineation thyroid nodules using a database that were unequivocally diagnosed by means histopathological examination meticulously matched with imaged nodules. Methods A total 165 patients having 251 histopathologically proven definitive diagnoses during 5-year period included study. All had preoperatively undergone...
Poor glycaemic control, hypertension and duration of diabetes are risk factors for the development diabetic nephropathy, but there may be genetic factors. Recently, a common C to T mutation at nucleotide position 677 MTHFR gene (MTHFR677C > T) has been reported correlated with hyperhomocysteinemia severity coronary artery disease as macroangiopathy. We aim investigate Turkish type 2 patients with/without nephropathy healthy group examine contribution polymorphism nephropathy.DNA was...
Oxidative stress is regarded as a pathogenic factor in hyperthyroidism. Our purpose was to determine the relationship between oxidative and inflammatory cytokines investigate how melatonin affects damage cytokine response thyrotoxic rats. Twenty-one rats were divided into three groups. Group A served negative controls. B had untreated thyrotoxicosis, C received melatonin. Serum malondialdehyde (MDA), glutathione (GSH), reductase (GR), peroxidase (GPx), nitric oxide derivates (NO*x), plasma...
Several studies have shown increased oxidative stress in patients with pre-diabetes and newly diagnosed Type 2 diabetes mellitus (T2DM). It has been proposed that initiates insulin resistance genetically predisposed individuals. The aim of this study was to evaluate the markers offspring T2DM.We examined 60 lean normoglycemic diabetics, 52 age, sex body mass index matched subjects without family history T2DM as controls. Anthropometric, biochemical carotid intima media thickness (IMT)...
We aimed to compare the ultrasonographic and laboratory parameters of euthyroid patients who have only positive antithyroid autoantibody test results with those a hypothyroid status Hashimoto's thyroiditis (HT).Thirty-five newly diagnosed HT, 35 autoantibodies against thyroid peroxidase (TPOAb) and/or thyroglobulin (TgAb), 40 controls were enrolled in study. Plasma free T3, T4, stimulating hormone, TPOAb, TgAb levels obtained retrospectively. For gray-scale ultrasonography, each gland all...
Obesity, insulin resistance and hyperandrogenism, crucial parameters of Polycystic ovary syndrome (PCOS) play significant pathophysiological roles in lipidemic aberrations associated within the syndrome. Parts metabolic (low HDL resistance) appeared to facilitate association between PCOS coronary artery disease, independently obesity. ABCA1 gene polymorphism may be altered this components patients.In study, we studied 98 patients 93 healthy controls. All subjects underwent venous blood...