A5100368908- Vibrio bacteria research studies
- Aquaculture disease management and microbiota
- Identification and Quantification in Food
- Bacterial biofilms and quorum sensing
- Legionella and Acanthamoeba research
- Marine Bivalve and Aquaculture Studies
- Antibiotic Resistance in Bacteria
- Heme Oxygenase-1 and Carbon Monoxide
- Plant Pathogenic Bacteria Studies
- Virus-based gene therapy research
- Probiotics and Fermented Foods
- S100 Proteins and Annexins
- RNA and protein synthesis mechanisms
- Amoebic Infections and Treatments
- Enterobacteriaceae and Cronobacter Research
- Bacteriophages and microbial interactions
Chinese Academy of Fishery Sciences
2021-2025
University of Louisville
2024
Qingdao National Laboratory for Marine Science and Technology
2023
Hainan University
2017-2022
Tropical Bioscience and Biotechnology Research Institute
2020-2022
South China Agricultural University
2014-2019
Aix-Marseille Université
2012
Centre National de la Recherche Scientifique
2012
North Sichuan Medical University
2007
Vibrio harveyi is a Gram-negative, halophilic bacterium that an opportunistic pathogen of commercially farmed marine vertebrate species. To understand the pathogenicity this species, genome V. QT520 was analyzed and compared to other strains. The results showed has two unique circular chromosomes three endogenous plasmids, totaling 6,070,846 bp with 45% GC content, 5,701 predicted ORFs, 134 tRNAs 37 rRNAs. Common virulence factors, including ACF, IlpA, OmpU, Flagellin, Cya, Hemolysin MARTX,...
Infections with the pathogenic free-living amoebae Naegleria fowleri can lead to life-threatening illnesses including catastrophic primary amoebic meningoencephalitis (PAM). Efficacious treatment options for these infections are lacking and mortality rate remains >95% in US. Glycolysis is very important infectious trophozoite lifecycle stage inhibitors of glucose metabolism have been found be toxic pathogen. Recently, human enolase 2 (ENO2) phosphonate developed as agents treat glioblastoma...
Haliotid herpesvirus 1 (HAHV-1) causes significant damage to the abalone aquaculture industry. Knowledge of HAHV-1 invasion and host defense mechanisms is limited due lack stable molluscan cell lines. The present study established an in vitro infection model using primary suspension cultures hemocytes from Haliotis diversicolor supertexta discus hannai. cytopathic effects on adherent-cultured both species were also investigated. DNA loads firstly monitored by means quantitative PCR during...
ABSTRACT Infections with the pathogenic free-living amoebae Naegleria fowleri can lead to life-threatening illnesses including catastrophic primary amebic meningoencephalitis (PAM). Efficacious treatment options for these infections are lacking and mortality rate remains >95% in US. Glycolysis is very important infectious trophozoite lifecycle stage inhibitors of glucose metabolism have been found be toxic pathogen. Recently, human enolase 2 (ENO2) phosphonate developed as agents treat...
High temperature is a risk factor for vibriosis outbreaks. Most vibrios are opportunistic pathogens that cause the mortality of aquatic animals at vibrio optimal growth (~25 °C), whereas dominant Vibrio kanaloae strain SbA1-1 isolated from natural diseased ark clams (Scapharca broughtonii) during cold seasons in this study. Consistent symptoms and histopathological features reappeared under an immersion infection with performed 15 °C. The pathogenicity difference was assessed different...
The stringent response mediated by the signal molecule (p)ppGpp is involved in to multiple environmental stresses and control of various physiological processes. Studies have revealed that strongly affects formation maintenance several bacterial biofilms. However, specific regulatory roles biofilms, especially expression genes related cell motility exopolysaccharides (EPSs) production, remain poorly understood. We recently reported two synthetase relA spoT from epizootic pathogen Vibrio...
Vibrio harveyi is one of the most serious bacterial pathogens to aquatic animals worldwide. Evidence mounting that coinfections caused by multiple are common in nature and can alter severity diseases marine animals. However, involving V. have received little attention mariculture. In this study, results pathogen isolation indicated coinfection was a overlooked risk for hybrid groupers (♀ Epinephelus polyphekadion × ♂ E. fuscoguttatus) reared an industrialized flow-through pattern Hainan...
We analyzed the resistance to expanded-spectrum cephalosporins of an Enterobacter cloacae clinical isolate, EC002, by transconjugation, isoelectric-focusing analysis, and cloning experiments. It produced two β-lactamases with isoelectric point values 5.4 8.7, corresponding TEM-141, a novel variant TEM-1, CTX-M-22, encoded transferable plasmid.
Recently, a skin ulcerative disease caused by Vibrio mimicus has led to heavy economic losses in catfish, including yellow southern and Zhengchuan catfish China. Currently, there was no effective method of controlling the outbreak this disease. In study, bacterial isolates were obtained from dying channel identified as V. mimicus, which consist formalin-inactivated (antigen). After first immunization, four weeks later, fishes exposed immune response analyzed: Fish survival, respiratory burst...
The Pacific oyster Crassostrea gigas is one of the most important cultured marine species around world. Production oysters in China has depended primarily on hatchery produced seeds since 2016, with successful introduction and development triploid oysters. However, seed supply threatened by recurring mass mortality events recent years. Vibriosis commonly encountered disease associated intensive culture hatcheries nurseries. Vibrio alginolyticus Bacillus hwajinpoensis were two strains...