A5064791921- Respiratory Support and Mechanisms
- Asthma and respiratory diseases
- Neonatal Respiratory Health Research
- Respiratory viral infections research
- Pneumonia and Respiratory Infections
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Inhalation and Respiratory Drug Delivery
- Sepsis Diagnosis and Treatment
- Congenital Diaphragmatic Hernia Studies
- Tracheal and airway disorders
- Obstructive Sleep Apnea Research
- Hemoglobinopathies and Related Disorders
- Airway Management and Intubation Techniques
- Neuroscience of respiration and sleep
- Nosocomial Infections in ICU
- Pneumocystis jirovecii pneumonia detection and treatment
- Inflammasome and immune disorders
- Hemodynamic Monitoring and Therapy
- Long-Term Effects of COVID-19
- Respiratory and Cough-Related Research
- Radiation Dose and Imaging
- Kawasaki Disease and Coronary Complications
- COVID-19 Clinical Research Studies
- Mechanical Circulatory Support Devices
- Pediatric health and respiratory diseases
Chulalongkorn University
2014-2024
King Chulalongkorn Memorial Hospital
2005-2023
Thai Red Cross Society
2019-2020
Pulmonary and Critical Care Associates
2017
Pediatrics and Genetics
2016
Royal Children's Hospital
1997-1998
Totally implantable vascular access devices (TIVADs) are accepted as a safe and effective method of facilitating long term intravenous therapy. We report our experience the use these in children with cystic fibrosis particular focus on incidence type complications.The medical records patients who underwent placement TIVAD at Royal Children's Hospital, Melbourne, Australia from January 1987 to October 1996 were reviewed. Venous ultrasonography Doppler was performed surviving situ November...
The jet nebulizer is a common device used for administering aerosol medication in young children. However, compared to metered dose inhaler-spacer (MDI-spacer), it takes more time and personnel. This study aimed compare the efficacy of salbutamol therapy given via these two devices wheezing A prospective randomized, double-blind, placebo-controlled trial was performed children up 5 years old who had acute were admitted Department Pediatrics, King Chulalongkorn Memorial Hospital. Patients...
To identify the incidence and factors related to upper gastrointestinal (UGI) bleeding in children requiring mechanical ventilation for longer than 48 hrs.Prospective analytic study.Ten-bed-pediatric intensive care unit of a tertiary University Hospital.A total 110 patients hrs from January 1, 2005 December 31, 2005.UGI was defined by evidence blood nasogastric aspirates, hematemesis, or melena within 5 days pediatric admission. We prospectively collected data on patient demographics,...
The cough mechanism is often impaired in children with quadriplegic spastic cerebral palsy, accounting for the high prevalence of pneumonia and atelectasis requiring prolonged hospitalization. Conventional chest physiotherapy (CPT) a current technique recommended at onset lower-respiratory infections palsy. Previous studies have demonstrated usefulness mechanical insufflation-exsufflation (MI-E) neuromuscular disease. To date, there has been no study MI-E objective to compare efficacy...
Smoking cessation is an achievable behavioral change, which reduces the risks of cardiovascular diseases, cancers and tobacco-related diseases. There a need for effective smoking service low middle income country settings where rate generally very high whilst not usually accessible. This study devised new package assessed its effectiveness in primary health care setting northern Thailand. randomized controlled trial was centered at Maetha district hospital, Lampang province, Thailand,...
Pulmonary disease is a common presenting feature and complication of T-cell immunodeficiency. We retrospectively reviewed 15 children with severe combined immune deficiency (SCID) 19 DiGeorge syndrome at the time their first presentation to Royal Children's Hospital in 15-year period from 1981 1995. In SCID, pulmonary was (67%) organisms identified were Pneumocystis carinii (PCP) (n = 7), bacteria 4), viruses 3), fungus 1). Late complications included lower respiratory tract infections,...
To determine the efficacy of lung volume recruitment maneuver (LVRM) with high frequency oscillatory ventilation (HFOV) on oxygenation, hemodynamic alteration, and clinical outcomes when compared to conventional mechanical (CV) in children severe acute respiratory distress syndrome (ARDS).We performed a randomized controlled trial enrolled pediatric patients who were diagnosed have ARDS upon intensive care unit (PICU) admission. LVRM protocol combined HFOV or was used. Baseline...
Viral respiratory tract infections are a major cause of hospitalization in children. Influenza is common but often not laboratory proven. We report prospective study children admitted with clinical diagnosis pneumonia. Infants and (ages 1 month-15 years) who were hospitalized community-acquired pneumonia enrolled the study. Their nasopharyngeal aspirated samples analyzed for viruses, including influenza virus, by reverse transcription-polymerase chain reaction (RT-PCR) or PCR. Out 257...
Pneumonia is the leading cause of pediatric morbidity and mortality worldwide, Mycoplasma pneumoniae Chlamydia are two most common atypical pathogens. This study was designed to determine prevalence clinical impact mycoplasma chlamydia pneumonia in children hospitalized with severe pneumonia. Children 1 month - 15 years old a diagnosis (WHO criteria) were recruited between March 2005 2006. Serologic studies performed for anti-M. anti-C. IgG/M on admission 2-4 weeks afterward using ELISA. Of...
To determine the incidence and associated factors of multidrug-resistant hospital-associated infections (MDR-HAI) in a pediatric intensive care unit (PICU) university hospital Thailand.A prospective study was performed PICU King Chulalongkorn Memorial Hospital during period May-December 2005. Children aged < or = 15 years who developed PICU-related HAI were studied.Forty-four patients (median age 6 months; male:female 1.4:1) 58 episodes HAI. The rate 28.3 per 1000 patient-days. Thirty (52%)...
Antileukotriene has been used for alleviating disease severity in children with adenotonsillar hypertrophy (ATH) and mild obstructive sleep apnea (OSA). Previous study showed the relationship between urinary cysteinyl leukotriene E₄ (uLTE₄) level therapeutic response to montelukast asthmatic adults. However, this never investigated pediatric OSA.To determine uLTE₄ ATH OSA.Children aged 3-15 yrs who had OSA were enrolled. All quality of life (assessed by Thai version OSA-18 QoL questionnaire)...
Severe sepsis and septic shock are major causes of morbidity mortality among children in pediatric intensive care units (PICUs) worldwide. Activated protein C (PC) is a critical endogenous regulator coagulation inflammation patients with sepsis. However, the role PC still obscure. We prospectively recruited infants aged between 1 month 15 years old who were admitted to PICU clinical diagnosis systemic inflammatory response syndrome, sepsis, or shock. Clinical data recorded blood samples kept...
IntroductIonRespiratory distress is one of the most common causes hospitalization in children worldwide. [1]Various forms oxygen therapy are used to treat who have respiratory distress.Oxygen supplement by nasal cannula infants and limited flow due insufficient humidification.If was more than 2-6 L/min, it will make cool dry airway. [2,3]Noninvasive positive pressure ventilation proved reduce need for endotracheal tube intubation, but could patient discomfort.Mechanical through an another...
The Belun ring is a new home sleep apnea testing device using pulse oximeter sensor and neural network algorithm, but its data in children are limited. This study aims to evaluate the correlation agreement of ring, compared with polysomnography (PSG) determine diagnostic accuracy for moderate-to-severe obstructive (OSA).
The long-term respiratory sequelae of COVID-19 infection in children remain poorly understood and may differ across countries. This study aims to investigate the sequelae, including residual symptoms pulmonary function Thai children. secondary aim is identify factors associated with sequelae.
Abstract Background Although previous studies have shown benefits of nebulized hypertonic saline (HS) for improving airway clearance and shortening hospitalization in infants with bronchiolitis, prospective blinded preschool children acute viral wheezing are limited. Objectives To determine 3% HS efficacy young admitted wheezing. Methods This double‐blind, randomized controlled trial was conducted aged 6 months to 5 years from July 1st December 31st 2016. Patients were receive inhalation 2.5...
Abstract The objectives of this study were to identify possible risk factors bronchial hyperesponsiveness (BHR) in children up 5 years age with wheezing‐associated respiratory infection (WARI), and the prevalence BHR. Children WARI enrolled study. parents or caregivers asked about their demographic data clinical histories. Physical examination score assessment performed. Pulmonary function tests, i.e., tidal breathing flow volume (TBFV), performed measure parameters before after salbutamol...