A5015220656- Glycosylation and Glycoproteins Research
- Plant Reproductive Biology
- Biochemical effects in animals
- Neurobiology and Insect Physiology Research
- Erythrocyte Function and Pathophysiology
- Caveolin-1 and cellular processes
- Microtubule and mitosis dynamics
- Neuropeptides and Animal Physiology
- Nuclear Structure and Function
- Lipid Membrane Structure and Behavior
- RNA and protein synthesis mechanisms
- Genetic and Kidney Cyst Diseases
Cedarville University
2013
The Ohio State University
1968-1971
Muhlenberg College
1968
The cAMP-dependent aquaporin-2 (AQP2) redistribution from intracellular vesicles into the plasma membrane of renal collecting duct principal cells induces water reabsorption and fine-tunes body homeostasis. However, mechanisms controlling localization AQP2 are not understood in detail. Using immortalized mouse medullary (MCD4) primary rat inner (IMCD) as model systems, we here discovered a key regulatory role Aurora kinase A (AURKA) control AQP2. AURKA-selective inhibitor Aurora-A I novel...
Tetrahymena thermophila are free-living, ciliated eukaryotes. Their behavioral response to stimuli is well characterized and easily observable, since cells swim toward chemoattractants avoid chemorepellents. Chemoattractant responses involve increased speed or a decreased change in direction, while chemorepellent signaling involves ciliary reversal, which causes the organism jerk back forth, small circles, spin an attempt get away from repellent. Many food sources, such as proteins, for...