Alexandra V. Kalpadakis-Smith

ORCID: 0000-0003-0568-9364
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About
Contact & Profiles
Research Areas
  • Visual perception and processing mechanisms
  • Ophthalmology and Visual Impairment Studies
  • Face Recognition and Perception
  • Retinal Development and Disorders
  • Neural and Behavioral Psychology Studies
  • Neural dynamics and brain function
  • Aesthetic Perception and Analysis
  • Healthcare Systems and Technology
  • Visual Attention and Saliency Detection
  • Clinical practice guidelines implementation
  • Digital Media and Visual Art
  • Health Systems, Economic Evaluations, Quality of Life
  • Optical Polarization and Ellipsometry
  • Color perception and design
  • Patient-Provider Communication in Healthcare
  • Delphi Technique in Research
  • Patient Satisfaction in Healthcare
  • Ocular and Laser Science Research

Bristol-Myers Squibb (United States)
2024

University College London
2015-2023

Royal Holloway University of London
2014

Visual crowding is the disruptive effect of clutter on object recognition. Although most prominent in adult peripheral vision, also disrupts foveal vision typically developing children and those with strabismic amblyopia. Do these effects share same mechanism? Here we exploit observations that crowded errors are not random: Target objects appear either averaged flankers (assimilation) or replaced by them (substitution). If amblyopic developmental mechanism, then their should be similarly...

10.1167/jov.22.6.3 article EN cc-by-nc-nd Journal of Vision 2022-05-04

While the use of electronic methods to collect patient-reported outcome data in clinical trials continues increase, it remains case that many measures (PROMs) have originally been developed and validated on paper. Careful consideration during move from paper PROMs format is required preserve integrity measure ensure a "faithful migration." Relevant literature has long called out importance following migration best practices this process; nevertheless, such are distributed across multiple...

10.1016/j.jval.2023.10.007 article EN cc-by-nc-nd Value in Health 2023-10-23

Abstract Crowding (the disruption of object recognition in clutter) presents the fundamental limitation on peripheral vision. For simple objects, crowding is strong when target/flanker elements are similar and weak they differ – a selectivity for target-flanker similarity. In contrast, identification upright holistically-processed face stimuli more strongly impaired by than inverted flankers, whereas face-targets both pattern attributed to an additional stage selective “holistic similarity”...

10.1038/s41598-018-30900-0 article EN cc-by Scientific Reports 2018-08-16

Abstract Background: In clinical trials, the single-item-per-screen format is commonly used for electronic patient-reported outcomes (ePROs). However, participant preferences this over multiple items per screen have not been investigated. This study evaluated vs. multiple-items-per-screen ePRO formats, effect on completion times, and comparability of scores between formats. Methods: Participation in randomized, crossover, observational involved both formats an tablet device during two...

10.21203/rs.3.rs-3921908/v1 preprint EN cc-by Research Square (Research Square) 2024-02-09

Whilst it is common for artists asking questions about the very nature of beauty, and universal aspects aesthetic experiences, such are rarely picked up by scientists. However, psychophysics can make this field enquiry accessible as demonstrated Fechner (1876) in his rather programmatic experimental aesthetics. A key issue to overcome attempts visual domain apparently huge range irregularity possible designs paintings, need use systematic well-defined stimuli psychophysics. On way towards...

10.1167/14.10.653 article EN cc-by-nc-nd Journal of Vision 2014-08-22

For children with strabismic amblyopia (a developmental disorder of vision linked ocular deviation), foveal can become affected by crowding: objects that are visible in isolation indistinguishable clutter. Crowding also affects the visual periphery adults, where it produces systematic errors object identification: target appears to be either averaged flanker identities (assimilation), or replaced them (substitution). If same mechanisms underlie crowding and adult periphery, then amblyopic...

10.1167/16.12.237 article EN cc-by-nc-nd Journal of Vision 2016-09-01

Crowding (the disruption of object recognition in clutter) presents the fundamental limitation on peripheral vision. For simple objects, crowding is strong when target/flanker elements are similar and weak they differ – a selectivity for target-flanker similarity. In contrast, identification upright holistically-processed face stimuli more strongly impaired by than inverted flankers, whereas face-targets both pattern attributed to an additional stage selective “holistic similarity” between...

10.31234/osf.io/2z8un preprint EN 2017-07-26

Crowding is the disruptive effect of clutter on object recognition. Despite affecting a range visual features, from colour to motion, most models characterise it as singular mechanism. Studies using faces have challenged this idea by proposing separate ‘holistic’ crowding stage (Louie, Bressler & Whitney, 2007). We first replicate holistic an identity-matching task: strong for upright target face (processed ‘holistically’) when surrounded flanker and weak inverted flankers. find no such...

10.1167/15.12.551 article EN cc-by-nc-nd Journal of Vision 2015-09-01

Crowding is the disruption to object recognition that occurs in clutter, a process strongly limits peripheral vision and becomes elevated foveal/central with amblyopia (‘lazy eye’). Bottom-up ‘pooling’ models depict crowding as an unwanted integration of target flanker elements, amount driven by similarity between elements. In contrast, top-down ‘grouping’ approaches argue follows Gestalt principles organisation. We reasoned if grouping, then wherever occurs, grouping effects should follow....

10.1167/jov.23.9.4805 article EN cc-by-nc-nd Journal of Vision 2023-08-01

Abstract Visual crowding is the disruptive effect of clutter on object recognition. Although most prominent in adult peripheral vision, also disrupts foveal vision typically-developing children and those with strabismic amblyopia. Do these effects share same mechanism? Here we exploit observations that crowded errors are not random: target objects appear either averaged flankers (assimilation), or replaced by them (substitution). If amblyopic developmental mechanism then their should be...

10.1101/2021.11.30.470647 preprint EN cc-by bioRxiv (Cold Spring Harbor Laboratory) 2021-12-02
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