A5076402822- Reproductive Biology and Fertility
- Ovarian function and disorders
- Mesenchymal stem cell research
- Tissue Engineering and Regenerative Medicine
- Liver physiology and pathology
- Assisted Reproductive Technology and Twin Pregnancy
- Reproductive System and Pregnancy
- Liver Disease Diagnosis and Treatment
- Circular RNAs in diseases
- Peroxisome Proliferator-Activated Receptors
- Organ Transplantation Techniques and Outcomes
- Long-Term Effects of COVID-19
- Clinical Nutrition and Gastroenterology
- MicroRNA in disease regulation
- Lipid metabolism and disorders
- COVID-19 Clinical Research Studies
Academic Center for Education, Culture and Research
2020-2025
Tehran University of Medical Sciences
2017-2020
Abstract Background Cell-free Mesenchymal stromal cells (MSCs) have been considered due to their capacity modulate the immune system and suppress cytokine storms caused by SARS-CoV-2. This prospective randomized double-blind placebo-controlled clinical trial aimed assess safety efficacy of secretome derived from allogeneic menstrual blood (MenSCs) as a treatment in patients with severe COVID-19 . Methods Patients were (1:1) either MenSC-derived or control group. Subjects received five...
Poor ovarian response (POR) significantly reduces the success rates of fertility treatments. This study investigates long-term efficacy and potential complications associated with autologous menstrual blood-derived mesenchymal stromal cells (MenSCs) therapy in improving outcomes for women POR. To evaluate MenSC longitudinal, single-center retrospective observational included 105 POR patients who received injections from August 2018 to September 2021. Participants were monitored at least 3...
Abstract Background Assisted reproduction faces a significant obstacle in the form of poor ovarian response (POR) to controlled stimulation. To address this challenge, mesenchymal stem cell therapy has been proposed as potential treatment for female infertility and/or restoration function POR women. Our previous research demonstrated that menstrual blood-derived-mesenchymal stromal cells (MenSCs) injected into ovaries women with can increase pregnancy rates. The objective study was examine...
The peroxisome proliferator-activated receptors (PPARs) are ligand-activated transcription factors that belong to the nuclear hormone receptor superfamily. Several studies have demonstrated a significant association between Pro12Ala polymorphism of PPAR-γ2 gene and metabolic disorders. Therefore, this study aimed evaluate with increased risk NAFLD in Iranian patients type 2 diabetes mellitus.This cross-sectional was performed on 145 healthy control subjects history diabetes. genotyping using...
Abstract Background The major obstacle associated with assisted reproduction is poor ovarian response (POR) to controlled stimulation. Consequently, mesenchymal stem cell therapy has been proposed as a potential treatment for female infertility and/or restoration of function in POR women. initial phase the study showed an increase pregnancy rate women who received menstrual blood-derived-mesenchymal stromal cells (MenSCs) into their ovaries. objective was evaluate whether this could improve...