A5064119061- RNA and protein synthesis mechanisms
- RNA modifications and cancer
- RNA Research and Splicing
- Genomics and Phylogenetic Studies
- Cancer-related molecular mechanisms research
- Cytokine Signaling Pathways and Interactions
- Hormonal Regulation and Hypertension
- Sexual Differentiation and Disorders
- Hormonal and reproductive studies
- interferon and immune responses
Adam Mickiewicz University in Poznań
2019-2021
Androgen insensitivity syndrome (AIS), manifesting incomplete virilization in 46,XY individuals, is caused mostly by androgen receptor (AR) gene mutations. Therefore, a search for AR mutations routine approach AIS diagnosis. However, some patients lack mutations, which complicates the Here, we describe patient suffering from partial (PAIS) and lacking The whole exome sequencing of his family members identified heterozygous FKBP4 mutation, c.956T>C (p.Leu319Pro), inherited mother. encodes...
Abstract Background The functions of RNA molecules are mainly determined by their secondary structures. These can also be predicted using bioinformatic tools that enable the alignment multiple RNAs to determine functional domains and/or classify into families. However, existing tools, which use structural information, slow in aligning long a large number molecules. Therefore, more rapid tool for may improve classification known and help reveal newly discovered RNAs. Results Here, we...
Abstract Background The functions of RNA molecules are mainly determined by their secondary structures. These can also be predicted using bioinformatic tools that enable the alignment multiple RNAs to determine functional domains and/or classify into families. However, existing tools, which use structural information, slow in aligning long a large number molecules. Therefore, more rapid tool for may improve classification known and help reveal newly discovered RNAs. Results Here, we...