- Phytochemistry and Biological Activities
- Biological and pharmacological studies of plants
- Plant and animal studies
- Natural product bioactivities and synthesis
- Ginseng Biological Effects and Applications
- Bioactive Natural Diterpenoids Research
- Analytical Methods in Pharmaceuticals
- Chemical synthesis and alkaloids
- Traditional and Medicinal Uses of Annonaceae
- Phytochemistry and biological activities of Ficus species
- Sesquiterpenes and Asteraceae Studies
- Essential Oils and Antimicrobial Activity
- Ethnobotanical and Medicinal Plants Studies
- Plant biochemistry and biosynthesis
- Pharmacological Effects of Medicinal Plants
- Hungarian Social, Economic and Educational Studies
- Cassava research and cyanide
- Allelopathy and phytotoxic interactions
- Plant chemical constituents analysis
- Synthetic Organic Chemistry Methods
- Mediterranean and Iberian flora and fauna
- Phytochemical Studies and Bioactivities
- Phytochemistry and Bioactivity Studies
- Biological Activity of Diterpenoids and Biflavonoids
- Phytochemical compounds biological activities
University of Szeged
2018-2024
Yeditepe University
2023
ole-gum-resin extracts (BSEs) are commonly used as food supplements, especially in osteoarthritis management. The quality standard is established by determining 11-keto-β-boswellic acid (KBA) and acetyl-11-keto-boswellic (AKBA) content using high-performance liquid chromatography (HPLC) or assessing the total boswellic (TBA) titrimetry. limited geographical distribution of
Continuing our search for bioactive compounds in species from the Juncaceae family, Juncus articulatus was investigated. Ten previously undescribed phenanthrenes─articulins A–J (1–10)─and ten known compounds─juncuenin B, dehydrojuncuenin juncatrin ensifolins E, F, H, I, K, juncuenin D, and luzulin A (11–20)─along with other compounds, have been isolated identified. The were evaluated antibacterial activity against Escherichia coli, Pseudomonas aeruginosa, methicillin-susceptible...
Species in the Juncaceae accumulate different types of secondary metabolites, among them phenanthrenes and 9,10-dihydrophenanthrenes substantial amounts. These compounds have chemotaxonomic significance also possess interesting pharmacological activities. The present study has focused on isolation, structure determination, investigation from Juncus gerardii. Twenty-six compounds, including 23 phenanthrenes, been isolated a methanol extract this plant. Twelve gerardiins A–L (1–12), were...
Monoterpene and 5-methylcoumarin- or 5-methylchromone-coupled meroterpenoids occurring mainly in the Asteraceae species proved to have high potency against protozoans, worms, various tumor cells, which make them interesting targets for searching new bioactive compounds. The African plant
Juncaceae family represents an abundant source of phenanthrenes. In continuation our work aiming at the isolation biologically active compounds from species, Juncus maritimus Lam. was subjected to phytochemical and pharmacological investigations. The process carried out by using combined extraction chromatographic methods. structures obtained chemical were elucidated spectroscopic analysis, including HRESIMS, 1D (1H, 13C-JMOD), 2D (1H-1H-COSY, HSQC, HMBC, NOESY) NMR spectra. Four new...
Abstract Juncus species are valuable sources of phenanthrene compounds that have been used in traditional Chinese medicine for thousands years. Effusol and juncusol the most investigated reported to antimicrobial anticancer effects; however, date, their effects on higher plants not investigated. In this study, we examined effusol growth other biochemical parameters dicot model plant Arabidopsis thaliana a concentration-dependent manner with focus polyamine metabolism. Phenanthrene induced...
Eight previously undescribed chromones, named pauciflorins F-M and two 5-methyl-2,4-chromadione derivatives as N O, were isolated from the methanol extract of leaves Centrapalus pauciflorus (Willd.) H.Rob. together with known (+)-spiro-ethuliacoumarin. The structures determined via extensive spectroscopic analyses, including HRESIMS, 1D NMR (1H, 13C JMOD), 2D (HSQC, HMBC, 1H-1H COSY, NOESY) experiments. Through an MTT assay, seven compounds tested for their antiproliferative properties...
Phenanthrenes are the main special metabolites of Juncaceae species from phytochemical, pharmacological, and chemotaxonomical points view. The present study focused on isolation, structure determination, pharmacological investigation phenanthrenes Juncus ensifolius. Nineteen compounds, including 17 phenanthrenes, were identified methanol extract plant. Thirteen namely, ensifolins A–M (1–13), obtained for first time natural sources. Four...
A previously unreported secoiridoid glycoside, cruciatoside (1) was isolated from the aerial parts of Gentiana cruciata L. along with ten known compounds eustomoside (2), eustomorusside (3), gentiopicroside (4), 6'-O-β-D-glucopyranosyl (5), loganic acid (6), isoorientin (7), isovitexin (8), 2''-(E)-ferulate (9), mangiferin (10), and 2-methyl-inositol (11). The chemical structures isolates were elucidated based on extensive 1 D 2 NMR experiments as well HRMS analysis. All evaluated for their...
Indonesia is among the countries with most significant biodiversity globally. Jamu, traditional medicine of Indonesia, predominantly uses herbal materials and an integral component Indonesian healthcare system. The present study reviewed ethnobotanical data seven Euphorbiaceae species, namely Euphorbia atoto, E. hypericifolia, Homalanthus giganteus, Macaranga tanarius, Mallotus mollissimus, M. rufidulus, Shirakiopsis indica, based on RISTOJA database other literature sources. An...
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Using various chromatographic methods, seven compounds, including two secoiridoid glycosides; depressine (1) and gentiopicroside (2), one iridoid glycoside; loganic acid (3), flavone-C-glycosides; isoorientin (4) isovitexin ( 5), xanthone-C-glycoside, mangiferin (6) as well a nucleoside; adenosine (7) were isolated from the MeOH extract prepared aerial parts of Gentiana asclepiadea L. Their structures elucidated unambiguously by spectroscopic methods such 1D 2D NMR HRESIMS.The...