A5052884239- Escherichia coli research studies
- Salmonella and Campylobacter epidemiology
- Mycobacterium research and diagnosis
- Gut microbiota and health
- Gastric Cancer Management and Outcomes
- Vibrio bacteria research studies
- Dermatology and Skin Diseases
- Oral health in cancer treatment
- Advanced Drug Delivery Systems
- Antibiotic Resistance in Bacteria
- Inflammatory Bowel Disease
- Probiotics and Fermented Foods
- Microscopic Colitis
- Inhalation and Respiratory Drug Delivery
University of British Columbia
2023-2025
British Columbia Children's Hospital
2023
University of Alberta
2022
Abstract NOT PUBLISHED AT THE AUTHOR’S REQUEST Funding Agencies: None
Abstract NOT PUBLISHED AT AUTHOR’S REQUEST Please acknowledge all funding agencies listed below Funding Agencies: CCC, CIHRWeston Family Foundation
Citrobacter rodentium is an attaching and effacing (A/E) pathogen used to model enteropathogenic enterohemorrhagic Escherichia coli infections in mice. During colonization, C. must adapt stresses the gastrointestinal tract, such as antimicrobial peptides, pH changes, bile salts. The Cpx envelope stress response (ESR) a two-component system by some bacteria remediate modulating gene expression, it necessary for pathogenesis Here, we utilized simulated colonic fluid (SCF) mimic environment,...
Abstract Background Inflammatory bowel disease (IBD) pathobionts are commensal microbes with pathogenic potential that may cause or exacerbate IBD symptoms. Some (ex. Escherichia coli) reside at low levels in the lumen of a healthy gut but can rapidly grow inflamed colons ulcerative colitis (UC) patients. To promote disease, these must cross colonic mucus barrier (comprised MUC2) separates epithelium from luminal microbes. It is currently unclear how bacterial UC Aims Using and patient...
Abstract Citrobacter rodentium is an attaching and effacing (A/E) pathogen used to model enteropathogenic enterohemorrhagic Escherichia coli infections in mice. During colonization, C. must adapt stresses the gastrointestinal tract such as antimicrobial peptides, pH changes, bile salts. The Cpx envelope stress response (ESR) a two-component system by some bacteria remediate modulating gene expression necessary for pathogenesis Here, we utilized simulated colonic fluid (SCF) mimic environment...
Abstract Citrobacter rodentium is an attaching and effacing (A/E) pathogen used as a model for enteropathogenic enterohemorrhagic Escherichia coli infections in mice. While the host, C. must adapt to stresses gastrointestinal tract such antimicrobial peptides, pH changes, bile salts. The Cpx envelope stress response (ESR) two-component system by some bacteria remediate modulating gene expression necessary pathogenesis To investigate genes regulon that may contribute pathogenesis, RNA-Seq,...