A5026834440- Graphene and Nanomaterials Applications
- Epigenetics and DNA Methylation
- RNA modifications and cancer
- ICT in Developing Communities
- Advanced Sensor and Energy Harvesting Materials
- Graphene research and applications
- Nanoplatforms for cancer theranostics
- Neuropeptides and Animal Physiology
- Receptor Mechanisms and Signaling
- Electrohydrodynamics and Fluid Dynamics
- Cancer-related gene regulation
- Signaling Pathways in Disease
Stanford University
2023
Ben-Gurion University of the Negev
2019-2021
University of Cambridge
2020
University of Chicago
2018
Adhesion G-protein-coupled receptors (aGPCRs) play critical roles in diverse cellular processes neurobiology, development, immunity, and numerous diseases. The lack of molecular understanding their activation mechanisms, especially with regard to the transmembrane domains, hampers further studies facilitate aGPCR-targeted drug development. Latrophilin-1/ADGRL1 is a model aGPCR that regulates synapse formation embryogenesis, its mutations are associated cancer attention-deficit/hyperactivity...
Interest in the pathogenesis, detection, and prevention of viral infections has increased broadly many fields research over past year. The development water treatment technology to combat infection by inactivation or disinfection might play a key role places where drinking sources are biologically contaminated. Laser-induced graphene (LIG) antimicrobial antifouling surface effects mainly because its electrochemical properties texture, LIG-based filters have been used for bacteria. However,...
DNA 5-methylcytosine (5mC)-specific mapping has been hampered by severe degradation and the presence of 5-hydroxymethylcytosine (5hmC) using conventional bisulfite sequencing approach. Here, we present a 5mC-specific whole-genome amplification method (5mC-WGA), with which achieved 5mC retention during from limited input down to 10 pg scale interference 5hmC signals, providing methylome high reproducibility accuracy.
Graphene in the form of laser-induced graphene (LIG) has antimicrobial and antifouling surface effects due to its electrochemical properties texture, LIG-based water filters were used for inactivation bacteria. However, antiviral activity LIGbased not been explored. Here we showed that LIG also have under application electrical potential using model prototypic poxvirus virus Vaccinia lister. This was compared with antibacterial activity, which higher voltages are required The generation...
FAM86A is a class I lysine methyltransferase (KMT) that generates trimethylation on the eukaryotic translation elongation factor 2 (EEF2) at Lys525. Publicly available data from The Cancer Dependency Map project indicate high dependence of hundreds human cancer cell lines expression. This classifies among numerous other KMTs as potential targets for future anticancer therapies. However, selective inhibition by small molecules can be challenging due to conservation within S-adenosyl...
Graphene in the form of laser-induced graphene (LIG) has antimicrobial and antifouling surface effects due to its electrochemical properties texture, LIG-based water filters were used for inactivation bacteria. However, antiviral activity LIGbased not been explored. Here we showed that LIG also have under application electrical potential using model prototypic poxvirus virus Vaccinia lister. This was compared with antibacterial activity, which higher voltages are required The generation...
ADVERTISEMENT RETURN TO ISSUEPREVAddition/CorrectionNEXTORIGINAL ARTICLEThis notice is a correctionCorrection to "DNA 5-Methylcytosine-Specific Amplification and Sequencing"Chang LiuChang LiuMore by Chang Liu, Xiaolong CuiXiaolong CuiMore Cui, Boxuan Simen ZhaoBoxuan ZhaoMore Zhao, Pradnya NarkhedePradnya NarkhedeMore Narkhede, Yawei GaoYawei GaoMore Gao, Jun LiuJun Xiaoyang DouXiaoyang DouMore Dou, Qing DaiQing DaiMore Dai, Li-Sheng ZhangLi-Sheng ZhangMore Zhang, Chuan He*Chuan HeMore...