Mridula Gupta

ORCID: 0000-0003-0620-7515
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About
Contact & Profiles
Research Areas
  • Insect Resistance and Genetics
  • Molecular Biology Techniques and Applications
  • Insect-Plant Interactions and Control
  • Research on scale insects
  • Genomics and Phylogenetic Studies
  • Viral Infectious Diseases and Gene Expression in Insects
  • Aquatic life and conservation
  • Insect Pest Control Strategies
  • RNA and protein synthesis mechanisms
  • Circadian rhythm and melatonin
  • Salmonella and Campylobacter epidemiology
  • RNA Research and Splicing
  • Sugarcane Cultivation and Processing
  • Agricultural pest management studies
  • Cocoa and Sweet Potato Agronomy
  • Cytomegalovirus and herpesvirus research
  • Date Palm Research Studies
  • Biological Control of Invasive Species
  • Gastric Cancer Management and Outcomes
  • Pineapple and bromelain studies
  • Agricultural Economics and Practices
  • Escherichia coli research studies
  • Venous Thromboembolism Diagnosis and Management
  • Bioactive Compounds and Antitumor Agents
  • HIV, Drug Use, Sexual Risk

Texas A&M University
2021-2025

Mitchell Institute
2024

Punjab Agricultural University
2018-2021

Lancashire Teaching Hospitals NHS Foundation Trust
2019

Guru Angad Dev Veterinary and Animal Sciences University
2016

Baba Farid University of Health Sciences
2016

All India Institute of Medical Sciences
1987-2012

DR. B.R.A. Institute Rotary Cancer Hospital
2012

Virginia Commonwealth University Medical Center
2000

Amrasca biguttula (Ishida) commonly known as cotton leafhopper is a severe pest of and okra. Not much on this insect at molecular level due to lack genomic transcriptomic data. To prepare for functional studies in insect, we evaluated 15 common housekeeping genes (Tub, B-Tub, EF alpha, GADPH, UbiCF, RP13, Ubiq, G3PD, VATPase, Actin, 18s, 28s, TATA, ETF, SOD Cytolytic actin) during different developmental stages under starvation stress. We selected early (1st 2nd), late (3rd 4th) stage nymphs...

10.1371/journal.pone.0191116 article EN public-domain PLoS ONE 2018-01-12

Circadian rhythms are innate biological systems that control everyday behavior and physiology. Furthermore, bilateral interaction between the host’s circadian rhythm gut microbes influences a variety of health ramifications, including metabolic diseases, obesity, mental GALT physiology microbiome population. Therefore, we studying correlation differential gene expression in chicken brain microbiota abundance during rhythms. To understand this, raised freshly hatched chicks under two...

10.3390/microorganisms13040789 article EN cc-by Microorganisms 2025-03-30

Thrips tabaci is a severe pest of onion and cotton. Due to lack information on its genome or transcriptome, not much known about this insect at the molecular level. To initiate studies in insect, RNA was sequenced; de novo transcriptome assembly analysis were performed. The RNAseq data used identify reference RNAi pathway genes insect. Additionally, feeding demonstrated T. for first time. From assembled 27,836 coding sequence (CDS) with an average size 1236 bp per CDS identified. About 85.4%...

10.1186/s12867-019-0123-1 article EN cc-by BMC Molecular Biology 2019-02-18

The whitefly Bemisia tabaci is a global invasive pest that causes substantial losses to agricultural crops worldwide either by feeding and transmitting plant viruses. Management of this with insecticides the biggest challenge due developed resistance. RNA interference (RNAi) has been shown be promising strategy control limit viruses spread. present study targets ten potential genes (AQP, CAL, CYCP, K-1, Hsp20, Hsp 40, Hsp70, Hsp90, SNF IAP) have implicated in various vital physiological...

10.3389/fphys.2020.00123 article EN cc-by Frontiers in Physiology 2020-03-02

Phenacoccus solenopsis is one of the major polyphagous crop pests in India. Inadequate genomic or transcriptomic resources have limited molecular studies this insect despite its huge economic importance. The existing sequence were supplemented through RNA sequencing, de novo transcriptome assembly and analysis, which generated 12, 925 CDS from 23,643 contigs with an average size 1077.5 bp per 85.1% positive BLAST hits NCBI Non redundant (nr) database. Twenty three genes involved RNAi...

10.1038/s41598-019-49997-y article EN cc-by Scientific Reports 2019-09-23

A camptothecin (CPT)-resistant cell line (MCF-7/C4) was established from MCF-7 cells by mutagenic treatment with methylmethanesulfonate and selection CPT. MCF-7/C4 is 30-fold resistant to CPT cross-resistant UV cis-dichlorodiammineplatinum(II) but not VP-16 or ionizing radiation. Topoisomerase I (top1)-mediated cleavable complexes in the presence of CPT, measured oligonucleotide assay alkaline elution, were similar both lines. Other top1 parameters such as protein, RNA levels, DNA relaxation...

10.1016/s0026-895x(25)09604-x article EN Molecular Pharmacology 1996-12-01

Phenacoccus solenopsis, the cotton mealybug (Hemiptera: Pseudococcidae), is one of major pests in India. Scanty information available on molecular studies this insect due to limited genomic or transcriptomic sequence data. With advancement sequencing technology, enormous and data are being generated, RNAi undertaken insects, which require reverse transcription quantitative polymerase chain reaction evaluation. These gene expression normalization mRNA levels with reference genes account for...

10.1093/jee/toy328 article EN Journal of Economic Entomology 2018-10-04

<title>Abstract</title> Background Circadian rhythms are innate biological systems that control everyday behavior and physiology. Furthermore, bilateral interaction between the host's circadian rhythm gut microbes influences a variety of health ramifications, including metabolic diseases, obesity, mental health. Several studies have revealed how neurological components interact with GALT physiology microbiome population in host. Keeping these factors regard, we studying correlation...

10.21203/rs.3.rs-4438538/v1 preprint EN cc-by Research Square (Research Square) 2024-05-31

An outbreak of rice swarming caterpillar, Spodoptera mauritia Boisduval occurred during kharif, 2012 in some parts Dibrugarh district Assam that caused considerable damage to crop its vegetative stage. The was so severe as high twleve caterpillar were found at the base plants day time peak period September and about 805 ha area kharif infested Khowang Tipling area. Moreover, mean larval population density/m2 observed 36.80 against 0.004 non-outbreak year. Standard Precipitation Index (SPI)...

10.5958/0974-8172.2018.00225.0 article EN Indian Journal of Entomology 2018-01-01

Amrasca biguttula (Ishida) commonly known as cotton leafhopper is a serious pest of and okra. Nutritional requirements or growth physiology for this insect has not been much till date. We developed artificial membrane feeding method which can be further used RNA interference studies. Main components diet were L-cysteine (5.0 mg), glycine (2.0 nicotinic acid (1.0 sucrose (500 K2HPO4(50 ZnCl2 (0.04 Thiamine HCl (0.25 Vitamin B6 Becosules capsule powder (Pfizer Limited, USA) Green food dye...

10.17504/protocols.io.ksgcwbw preprint EN 2017-11-13
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