A5026951446- Graphene research and applications
- Graphene and Nanomaterials Applications
- Metabolism, Diabetes, and Cancer
- Cancer, Hypoxia, and Metabolism
- Pharmacological Effects and Toxicity Studies
- Carbon and Quantum Dots Applications
- Cancer, Lipids, and Metabolism
- Pancreatic function and diabetes
- Colorectal Cancer Treatments and Studies
- Nanoparticles: synthesis and applications
- PI3K/AKT/mTOR signaling in cancer
- Advanced Sensor and Energy Harvesting Materials
University of Stavanger
2021-2024
Abstract The scalable production of two-dimensional (2D) materials is needed to accelerate their adoption industry. In this work, we present a low-cost in-line and enclosed process exfoliation based on high-shear mixing create aqueous dispersions few-layer graphene, large scale with Y w ~ 100% yield by weight throughput ϕ 8.3 g h −1 . minimises basal plane defects compared traditional beaker-based shear which attribute reduced Reynolds number, Re 10 5 We demonstrate highly conductive...
Cancer cells exhibit altered metabolism, a phenomenon described century ago by Otto Warburg. However, metabolic drug targeting is considered an underutilized and poorly understood area of cancer therapy. Metformin, commonly used to treat type 2 diabetes, has been associated with lower incidence, although studies are inconclusive concerning effectiveness the in treatment or prevention. The aim this study was determine how glucose concentration influences cells' response metformin,...
Graphene-based drug carriers provide a promising addition to current cancer delivery options. Increased accessibility of high-quality graphene made by plasma-enhanced chemical vapor deposition (PE-CVD) makes it an attractive material revisit in comparison the widely studied oxide (GO) delivery. Here, we show potential repurposing metabolic phenformin for treatment terms stability, binding, and pH-responsive release. Using covalent attachment poly(ethylene glycol) (PEG) onto pristine...
Graphene is an attractive choice for the development of effective drug carrier in cancer treatment due to its high adsorption area and pH-responsive affinity. In combination with highly potent metabolic phenformin, increased doses could be efficiently delivered cells. This study compares use graphene oxide (GO) polyethylene glycol stabilized (PEGylated) pristine nanosheets (PGNSs) delivery applications phenformin. The cytotoxicity mitotoxicity graphene-based systems were assessed human cells...
Graphene, a material composed of two-dimensional lattice carbon atoms, has due to its many unique properties wide array potential applications in the biomedical field. One most common production methods is exfoliation through sonication, which simple but low yields. Another approach, using microfluidization, shown promise scalability for commercial production. Regardless their method, materials made need be tested biocompatibility. Here, we investigated differences toxicity, macrophage...
Graphene-based drug carriers provide a promising addition to current cancer 8 delivery options. Increased accessibility of high-quality graphene made by plasma- enhanced chemical vapor deposition (PE-CVD) makes it an attractive material re-visit in comparison the widely studied oxide (GO) delivery. Here we show potential re-purposing metabolic phenformin for treatment terms stability, binding, and pH-controlled release. Using covalent attachment polyethylene glycol (PEG) onto pristine...
Graphene-based drug carriers provide a promising addition to current cancer 8 delivery options. Increased accessibility of high-quality graphene made by plasma- enhanced chemical vapor deposition (PE-CVD) makes it an attractive material re-visit in comparison the widely studied oxide (GO) delivery. Here we show potential re-purposing metabolic phenformin for treatment terms stability, binding, and pH-controlled release. Using covalent attachment polyethylene glycol (PEG) onto pristine...