Larry Hartzell

ORCID: 0000-0003-0625-221X
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About
Contact & Profiles
Research Areas
  • Cleft Lip and Palate Research
  • Tracheal and airway disorders
  • Craniofacial Disorders and Treatments
  • Vascular Malformations and Hemangiomas
  • Obstructive Sleep Apnea Research
  • Reconstructive Facial Surgery Techniques
  • Reconstructive Surgery and Microvascular Techniques
  • Ear Surgery and Otitis Media
  • Airway Management and Intubation Techniques
  • Dysphagia Assessment and Management
  • Head and Neck Surgical Oncology
  • Congenital Ear and Nasal Anomalies
  • Meningioma and schwannoma management
  • Neonatal and fetal brain pathology
  • Tumors and Oncological Cases
  • Global Health and Surgery
  • Vestibular and auditory disorders
  • Oral and Maxillofacial Pathology
  • Bone and Dental Protein Studies
  • Delphi Technique in Research
  • Teratomas and Epidermoid Cysts
  • Genomics and Rare Diseases
  • Genomic variations and chromosomal abnormalities
  • Hemispheric Asymmetry in Neuroscience
  • Antenna Design and Analysis

University of Arkansas for Medical Sciences
2013-2025

Arkansas Children's Hospital
2010-2024

Objective The reported prevalence of cleft lip and palate within the state Arkansas (10.63 to 12.22 per 10,000 live births) is much higher than national average. With greater understanding at-risk populations risk factors, we can provide more targeted education improve patient outcomes potentially reduce incidence orofacial clefts. Design This a database review and/or patients using data obtained from Reproductive Health Monitoring System (ARHMS) database, statewide birth defects registry...

10.1177/10556656251326443 article EN cc-by The Cleft Palate-Craniofacial Journal 2025-03-17

Tracheostomy wounds are commonly encountered in children but rarely reported. Relatively few treatments available or have been investigated to manage this problem. Healing times for pediatric tracheostomy often unpredictable and protracted. Recent use of maltodextrin gel (MD) a silver alginate sponge (AG) at our institution has demonstrated expedited healing interest novel treatment wounds.We conducted an 11-month retrospective review with wound complications following placement tertiary...

10.4187/respcare.02822 article EN Respiratory Care 2014-08-05

To evaluate free tissue transfer (FTT) as a safe and effective reconstructive technique to treat arteriovenous malformations. Vascular lesions that present significant clinical challenge the head neck surgeon are often difficult can leave large, complex defects.Retrospective, single-institution case series.We describe 8 patients treated for extensive in various parts of reconstructed with flaps. These malformations have tendency recur, which was 75% our (6 8) during mean follow-up period 5...

10.1001/archfacial.2009.6 article EN Archives of Facial Plastic Surgery 2009-05-01

Objective: To assess the diagnostic accuracy and safety of office-based tracheoscopy when combined with flexible fiberoptic laryngoscopy (FFLT).Flexible on infants is routinely performed by otolaryngologists in clinic.The addition may improve overall airway assessment but rarely due to suspected risk compromise.Design: A 6-year retrospective medical record review.Setting: Tertiary care hospital.Patients: Thirty-one younger than 1 year complete data from preoperative FFLT microlaryngoscopy...

10.1001/archoto.2009.204 article EN Archives of Otolaryngology - Head and Neck Surgery 2010-01-18

To characterize the radiographic dental phenotype of individuals with SATB2-associated syndrome (SAS). Participants were evaluated by a multidisciplinary team during concurrent clinic conducted 1st international SAS family meeting held in 2017 at single institution. Whenever possible, panoramic and/or periapical radiographs obtained or previously and provided caregiver. Of 37 evaluated, 18 (12 males, median age 8.5 years) underwent examination. Dental revealed anomalies all starting 2 years...

10.1007/s00784-018-2702-9 article EN cc-by Clinical Oral Investigations 2018-10-12

Objective Assess interrater agreement of endoscopic assessment velopharyngeal (VP) function before and after viewing the video instruction tool (VIT). We hypothesized improvement in using Golding‐Kushner scale (GKS) VIT. Study Design Prospective study. Setting Multi‐institutional. Methods Sixteen fellowship‐trained pediatric otolaryngologists who treat insufficiency (VPI) rated 50 segments GKS watching Raters assessed gap size percentage lateral pharyngeal wall (LPW), soft palate (SP),...

10.1177/0194599818822989 article EN Otolaryngology 2019-01-15

This report describes the presentation of a newborn male with circumferential tongue-palate fusion associated cleft palate and alveolar bands. After intraoral adhesions lysis, patient was diagnosed Pierre Robin sequence. A family history lip noted, interferon regulatory factor 6 ( IRF6) sequencing revealed heterozygous variant, confirming diagnosis van der Woude syndrome. The disruption IRF6 resulted in abnormal orofacial development including micrognathia as well fusion, then resulting...

10.1177/1055665618773192 article EN The Cleft Palate-Craniofacial Journal 2018-04-30

To evaluate free tissue transfer (FTT) as a safe and effective reconstructive technique to treat arteriovenous malformations. Vascular lesions that present significant clinical challenge the head neck surgeon are often difficult can leave large, complex defects. Retrospective, single-institution case series. We describe 8 patients treated for extensive in various parts of reconstructed with flaps. These malformations have tendency recur, which was 75% our (6 8) during mean follow-up period 5...

10.1001/archfaci.2009.6 article EN Archives of Facial Plastic Surgery 2009-05-01

The ability to competently suture is an expected skill for graduating medical students, but many graduates report feeling unprepared perform this skill. This study aimed improve student confidence and clinical readiness third-year clerkships by implementing a novel, mandatory 7.5-hour longitudinal suturing skills curriculum across the first 3 years of school.The required was implemented all students throughout school at large academic health center in mid-South United States. Precurriculum...

10.14423/smj.0000000000001612 article EN Southern Medical Journal 2023-10-01

Background: The GILLS (gastroesophageal reflux, preoperative intubation, late intervention (>14 days), low birth weight (<2500 g), and syndromic diagnosis) score is a validated predictor of success for tongue-lip adhesion (TLA) in patients with Robin sequence (RS). Objective: To evaluate the application to mandibular distraction osteogenesis (MDO) airway management RS associated syndromes. Methods: A retrospective chart review 21 diagnosed treated MDO surgery between years 2006 2016 was...

10.1089/fpsam.2020.0436 article EN Facial Plastic Surgery & Aesthetic Medicine 2021-04-20

To determine outcomes of type 1 cartilage tympanoplasty in a cohort pediatric patients with history cleft palate repair.Retrospective chart review and comparison historical control group no anomaly undergoing the same procedure by surgeon at tertiary care hospital. A total 37 between ages 4 19 years inclusive (45 ears), repaired palate, underwent or without primary tube insertion from September 2004 to October 2012. Demographics, surgical indication, middle ear status, complications,...

10.1097/mao.0000000000000473 article EN Otology & Neurotology 2014-06-19

Tessier No 3 facial cleft (oro-nasal-ocular clefts) is the rarest and most challenging of all clefts. Reports on clinical findings, surgical techniques, outcomes are varied due to scarcity patients wide range phenotypic findings. The authors present our experience 2 children born with clefts who were both managed at Arkansas Children's Hospital. Our purpose add knowledge this rare craniofacial by providing detailed soft tissue skeletal operative early postoperative outcome, suggestions a...

10.1097/scs.0000000000004634 article EN Journal of Craniofacial Surgery 2018-06-05

To determine whether the presence of detectable upper respiratory infections (URIs) at time adenoidectomy/adenotonsillectomy is associated with increased morbidity, complications, and unexpected admissions.

10.1002/lary.29236 article EN cc-by-nc-nd The Laryngoscope 2020-11-05

Describe the first hybrid global simulation-based comprehensive cleft care workshop, evaluate impact on participants, and compare experiences based in-person versus virtual attendance.Cross-sectional survey-based evaluation.International workshop.Total of 489 participants.Three-day workshop.Participant demographic data, perceived barriers interventions needed for delivery, participant workshop satisfaction, short-term practice stratified by attendance.The included participants from 5...

10.1177/10556656221097820 article EN The Cleft Palate-Craniofacial Journal 2022-05-09

Characterized by developmental delay with severe speech delay, dental anomalies, cleft palate, skeletal abnormalities, and behavioral difficulties, SATB2-associated syndrome (SAS) is caused pathogenic variants in SATB2. The SAS phenotype range of severity has been documented previously large series. Using data from the registry, we present score, a comprehensive scoring rubric that encompasses 15 different individual neurodevelopmental systemic features. Higher (more severe) total (sum...

10.1155/2023/8200176 article EN Human Mutation 2023-04-26

Objective The addition of a uvular flap (PFU) was hypothesized to improve outcomes over standard pharyngeal (PF) for correction velopharyngeal dysfunction. We report differences in PF vs PFU at our institution. Design Retrospective cohort study. Setting Tertiary children's hospital. Patients Children who underwent or with the three highest-volume surgeons institution 2004-2017. Outcome measures examined complications between groups, frequency and type revision surgery, speech-related...

10.1177/10556656231172642 article EN The Cleft Palate-Craniofacial Journal 2023-05-04

Objective To examine whether a preoperative hemoglobin of less than 10 g/dL is associated with higher rate perioperative complications. Design Retrospective review. Setting Tertiary academic hospital at Arkansas Children's Hospital Little Rock, Arkansas. Patients A retrospective chart review evaluated patients undergoing primary cleft lip surgery from 2012 to 2017. Interventions No prospective intervention was performed for this study care. Main Outcome Measures Age, sex, medical history,...

10.1177/10556656241239510 article EN The Cleft Palate-Craniofacial Journal 2024-03-15
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