A5078335216- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Reproductive biology and impacts on aquatic species
- Animal Genetics and Reproduction
- Microbial metabolism and enzyme function
- Sperm and Testicular Function
- Sexual Differentiation and Disorders
- Mesenchymal stem cell research
- Cancer Cells and Metastasis
- Adsorption and biosorption for pollutant removal
- Advanced Cellulose Research Studies
- Inflammatory mediators and NSAID effects
- Bone Metabolism and Diseases
- Fish Biology and Ecology Studies
- Nanomaterials for catalytic reactions
- Cancer, Hypoxia, and Metabolism
- Biochemical Acid Research Studies
- Agronomic Practices and Intercropping Systems
- Plant-based Medicinal Research
- Identification and Quantification in Food
- Coronary Artery Anomalies
- Genomics, phytochemicals, and oxidative stress
- Metal Alloys Wear and Properties
- TGF-β signaling in diseases
- Macrophage Migration Inhibitory Factor
- Cancer-related gene regulation
Guangdong Ocean University
2019-2024
Hunan University
2014-2024
Second Affiliated Hospital of Xi'an Jiaotong University
2024
Second Military Medical University
2021
Shanghai Changzheng Hospital
2021
Hanzhong People's Hospital
2020
Changsha University
2015
Nanjing Medical University
2015
Nanjing Traditional Chinese Medicine Hospital
1980
The cost-effective material NTAA-LCM could be promising in the elimination of heavy metals from acidic or neutral wastewater.
The spotted scat, Scatophagus argus is a member of the family Scatophagidae found in Indo-Pacific coastal waters. It an emerging commercial aquaculture species, particularly East and Southeast Asia. In this study, first chromosome-level genome S. was constructed using PacBio Hi-C sequencing technologies. 572.42 Mb, with scaffold N50 24.67 Mb. Using data, 563.28 Mb (98.67% genome) sequences were anchored oriented 24 chromosomes, ranging from 12.57 to 30.38 assembly high integrity, containing...
Most patients diagnosed with pancreatic cancer are initially at an advanced stage, and radiotherapy resistance impact the effectiveness of treatment. This study aims to investigate effects endocrine disruptor Di-(2-ethylhexyl) phthalate (DEHP) on various biological behaviors sensitivity cells, as well its potential mechanisms. Our findings indicate that exposure DEHP promotes proliferation including those from lung, breast, pancreas, liver, in a time- concentration-dependent manner....
The spotted scat, Scatophagus argus, is a species of fish that widely propagated within the Chinese aquaculture industry and therefore has significant economic value. Despite this, studies its genome are severely lacking. In present study, genomic survey S. argus was conducted using next-generation sequencing (NGS). total, 55.699 GB (female) 51.047 (male) high-quality sequence data were obtained. Genome sizes estimated to be 598.73 597.60 Mbp. repeat ratios calculated 27.06% 26.99% (male)....
In vertebrate the development of gonad into testis or ovary requires combined effect genes and hormones to trigger differentiation from a bipotential gonadal primordium. Knowledge process is vital in studies on fish sex determination differentiation. The spotted scat (Scatophagus argus) an economically important marine with XX/XY sex-determining system exhibits sexual growth dimorphism favor females. Meanwhile, information gene expression patterns early gonads unknown. This study explores...
Gonadal somatic cell-derived factor (Gsdf) is a member of the TGF-β superfamily, which exists mainly in fishes. Homozygous gsdf mutations Japanese medaka and zebrafish resulted infertile females, reasons for their infertility remain unknown. This study presents functional studies Gsdf ovary development using CRISPR/Cas9 Nile tilapia (Oreochromis niloticus). The XX wild type (WT) female fish regularly reproduced from 12 months after hatching (mah), while gsdf-/- never were infertile....
Spotted scat ( Scatophagus argus ) is an important mariculture fish that of great economic significance in East and Southeast Asia. To date, there are no studies on ovary development regulation S. . Herein, the transcriptome profiles at different stages were constructed, genes pathways potentially involved secondary follicle growth identified. A total 25,426 detected by sequencing mRNAs from libraries stage III (n=3) IV (n=3). Notably, 2950 716 up-regulated down-regulated ovary,...
The reproductive-related studies, including genetic and genomic such as gonadal transcriptome analyses, have previously focused on the adult spotted scat, with little information juvenile fish. Transcriptomics is a powerful tool that allows for massive parallel analysis to identify differential expression patterns of gene holistically at particular stage in cell or tissue development. This study presents first report differentiating (juvenile; 4 months after hatch; I ovary testis) scat...
Pyrroloquinoline quinone (PQQ) has been demonstrated to function as an antioxidant by scavenging free radicals and subsequently protecting the mitochondria from oxidative stress-induced damage. The aim of present study was investigate whether PQQ is able rescue premature senescence in liver, induced deletion B cell-specific Moloney MLV insertion site-1 (Bmi-1), inhibiting stress. In vivo, mice were allocated into three groups that underwent following treatment protocols. WT received a normal...
The aim of the present study was to investigate whether pyrroloquinoline quinine (PQQ) serve a radioprotective role in parotid gland damage induced by total body irradiation (TBI) C57BL/6J mice. A 15 female 8-week-old mice were randomly assigned into three treatment groups: i) Untreated control (no irradiation); ii) 4 gray (Gy) X-ray irradiation; iii) Gy with additional dietary PQQ (4 mg PQQ/kg normal diet). Each group included five After weeks, all animals collected for evaluating...
Unlike mammals and birds, many fishes have young sex chromosomes, providing excellent models to study chromosome differentiation at early stages. Previous studies showed that spotted scat possesses an XX-XY determination system. The X has a complete Dmrt3 copy (termed normal) truncated of Dmrt1 (called Dmrt1b), while the Y opposite (normal Dmrt1, which is male-specific, called Dmrt3△-Y). candidate gene, other sex-linked genes remains unknown. proven be good model evolution chromosomes in...
Objective: To investigate the effect of Er:YAG laser irradiation on shear bond strength (SBS) and microleakage self-glazed zirconia (SZ) ceramics. Background: SZ is a novel type ceramic; has started to be used in surface treatment different ceramics, while been rarely studied improve quality. Methods: One hundred twenty blocks (5 mm × 5 mm) ceramics were produced split into eight groups following treatments (n = 15): Group A: no treatment; B: standard grid processing; C–H: power settings...
Spotbanded scat (Selenotoca multifasciata) has become a valuable marine culturing fish species in the southeast coastal areas of China. Herein, sex-linked markers were developed spotbanded to elucidate its genetic foundation sex determination. Eighty-four (84) cultured randomly chosen and used screen test markers. The average weight female (249 g, n = 32) is significantly higher than that male (212 52). whole genome was sequenced using next-generation sequencing technology. Phylogenetic...