A5003763397- Crystallization and Solubility Studies
- X-ray Diffraction in Crystallography
- Crystallography and molecular interactions
- Bone Tissue Engineering Materials
- Collagen: Extraction and Characterization
- Chemical Thermodynamics and Molecular Structure
- Crystal structures of chemical compounds
- Metal-Organic Frameworks: Synthesis and Applications
- Thermodynamic properties of mixtures
- Calcium Carbonate Crystallization and Inhibition
- Chemical Synthesis and Characterization
- Dental materials and restorations
- Bone health and treatments
- Phase Equilibria and Thermodynamics
- biodegradable polymer synthesis and properties
- Nanocomposite Films for Food Packaging
- Orthopaedic implants and arthroplasty
- Bone health and osteoporosis research
- Silk-based biomaterials and applications
- Molecular Sensors and Ion Detection
- Nanoparticles: synthesis and applications
- Bone Metabolism and Diseases
- Dental Implant Techniques and Outcomes
- Supramolecular Chemistry and Complexes
- Solid-state spectroscopy and crystallography
University of Bologna
2015-2024
GNA University
2021
Institute of Organic Synthesis and Photoreactivity
2004-2009
TARH (Portugal)
2005
École Centrale Paris
2005
Centre National de la Recherche Scientifique
2005
Kneading them in: A versatile porous material based on the 1D coordination network [CuCl2(dace)]∞ (dace=trans-1,4-diaminocyclohexane) can be inexpensively prepared by a mechanochemical reaction followed mild thermal treatment. The system is able to reversibly absorb molecules from solution or simple kneading, while guest desorption product invariably leads back unsolvated form.
β-tricalcium phosphate (β-TCP) is one of the most common bioceramics, widely applied in bone cements and implants. Herein we synthesized β-TCP by solid state reaction presence increasing amounts two biologically active ions, namely strontium zinc, order to clarify structural modifications induced ionic substitution. The results X-ray diffraction analysis indicate that zinc can substitute for calcium into a structure up about 10 at% inducing reduction cell parameters, whereas substitution...
Abstract In vitro bioactivity of gelatin sponges and hydroxyapatite‐enriched was tested through evaluation the variations in their composition morphology after soaking simulated body fluid (1.5) for periods up to 21 days at 37°C. The presence hydroxyapatite inside promotes deposition bonelike apatite crystals. deposits are laid down as spherical aggregates, with mean diameters increasing from about 1–2 μm, 4 solution, 3.5 μm samples soaked days. Simultaneously, relative amount inorganic...
Mechanical mixing of solid dicarboxylic acids variable chain length HOOC(CH(2))(n)COOH (n = 1-7) with 1,4-diazabicyclo[2.2.2]octane generates the corresponding salts or co-crystals formula [N(CH(2)CH(2))(3)N]-H-[OOC(CH(2))(n)COOH] (n=1-7). Preparation same systems from solution has been instrumental for a full characterization mechanochemical products by means single-crystal and powder-diffraction X-ray analyses, as well solid-state NMR. The acid-base adducts, whether involving proton...
Alendronate incorporation into hydroxyapatite nanocrystals: a novel approach allows the preparation of composite materials and opens new perspectives on chemical structural interactions between bisphosphonates bone mineral phase. Supporting information for this article is available WWW under http://www.wiley-vch.de/contents/jc_2089/2007/c2497_s.pdf or from author. Please note: The publisher not responsible content functionality any supporting supplied by authors. Any queries (other than...
Three crystal forms of the co-crystal 4,4'-bipy/pimelic acid (bipy: bipyridine), [NH(4)C(5)-C(5)H(4)N][HOOC(CH(2))(5)COOH], have been prepared and their relationship investigated by single-crystal X-ray diffraction, variable-temperature powder differential scanning calorimetry solid-state NMR spectroscopy. Both spectroscopic results indicate that no proton transfer takes place, is, three are true co-crystals neutral molecules. Forms I II both convert into Form III at high temperature, being...
The effect of the film-forming solution pH on triple-helix content, thermal stability, and mechanical properties gelatin films was investigated. were prepared from solutions at different pHs type A pigskin gelatin, their characteristics determined. At higher than 9 lower 5, Young’s modulus, E, stress break, σ b , decreased significantly. Cross-linking with genipin reduced deformation ϵ increased modulus. intensity 1.1-nm X-ray diffraction reflection denaturation enthalpy these pHs,...
Enthalpies of mixing, heat capacities, densities, viscosities, and refractive indices dimethyl sulfoxide + carbonate, diethyl propylene carbonate have been measured at 308.15 K atmospheric pressure using a LKB microcalorimeter, Perkin-Elmer differential scanning calorimeter, an Anton Paar density meter, Schott-Geräte AVS unit, Abbe refractometer, respectively. Heat capacities pure components were determined in the range (293.15 < T/K 423.15). The results fitted to Redlich−Kister polynomial...
We have explored the possibility of introducing biologically relevant ions, namely Sr2+, Mg2+, and Mn2+, into structure octacalcium phosphate (OCP). OCP with partial substitutions Sr2+ Mg2+ for Ca2+ up to 7.4 1.0 at%, respectively, was successfully synthesized. On contrary, Mn2+ completely inhibits crystallization, it promotes precipitation brushite. The incorporation disturbs shape crystals reduces stability structure. analysis structural modifications occurring during heat treatment puts...
Bone cell response to 3D bioinspired scaffolds was tested on osteoblast culture supernatants and by means of quantitative polymerase chain reaction (qPCR). Foaming freeze-drying method optimized in order obtain three-dimensional interconnected porous gelatin at different contents nanocrystalline hydroxyapatite (HA). Addition a non toxic crosslinking agent during foaming stabilized the scaffolds, as confirmed slow relatively low release phosphate buffer up 28 days. Micro-computed tomography...
Objective: The use of nanoparticles (NPs) in cancer diagnosis and treatment is a rapidly developing area nanotechnology. main objective this research work to synthesize copper oxide (CuO) NPs investigate its vitro anticancer antibacterial property. Methods: CuO were synthesized via facile cost-effective precipitation method using cupric acetate (monohydrate) (CuAc 2 .2H O), sodium hydroxide, glacial acetic acid. By varying the pH precursor solution, morphology, particle size, reaction rate...
Monetite and brushite are regarded with increasing interest for the preparation of biomaterials applications in musculoskeletal system. Herein, we investigated influence strontium substitution structures these two phosphates on bone cell response. To achieve this aim, co-cultures human primary osteoclasts osteoblast-like MG63 cells were tested strontium-substituted monetite brushite, as well controls. In both structures, calcium amounted to about 6 at% provoked enlargement parameters...
Hydroxyapatite–poly-L-aspartic acid (HA-PASP) and hydroxyapatite–polyacrylic (HA-PAA) composite crystals have been prepared by direct synthesis in aqueous solution. The polyelectrolytes are quantitatively incorporated into the up to about 8–9 wt%, as a function of their concentration structural morphological properties vary polyelectrolyte content. TEM images show that display greater length/width ratio with respect control HA crystals. broadening X-ray diffraction reflections on increasing...
The organometallic complex [Fe(η5-C5H4–C5H4N)2] has been reacted with the anthranilic acid (C6H4)NH2COOH to generate hydrogen bonded supramolecular macrocycle {[Fe(η5-C5H4–C5H4N)2] [(C6H4)NH2COOH]}2. product fully characterized by means of X-ray powder diffraction, 13C and 15N solid-state NMR single crystal diffraction. It shown that same can be obtained, quantitatively, three different processes, namely kneading, i.e. mixing in presence a catalytic amount MeOH, wet compression, pressure...
Molar heat capacities, Cp, densities, ρ, dynamic viscosities, η, and refractive indices, nD, for the binary mixtures poly(ethylene glycol) 200 400 + 2-methyltetrahydrofuran (MTHF) were determined at (293.15, 303.15, 313.15) K using a Perkin-Elmer differential scanning calorimeter, an Anton Paar density meter, Schott-Geräte AVS unit, Abbe refractometer, respectively. Excess molar volumes, , deviations of Δη, ΔR, calculated these temperatures. These properties fitted to Redlich−Kister equation.