A5067516297- Peripheral Neuropathies and Disorders
- Multiple Sclerosis Research Studies
- Hereditary Neurological Disorders
- Congenital Anomalies and Fetal Surgery
- Neurogenetic and Muscular Disorders Research
- Retinal Imaging and Analysis
- RNA modifications and cancer
- Retinal and Optic Conditions
Ural State Medical University
2015-2022
Regional Children's Clinical Hospital No. 1
2017-2021
Background . The efficacy and safety of onasemnogene abeparvovec have been demonstrated in patients with spinal muscular atrophy (SMA) several clinical observational studies. Gene replacement therapy results Russian SMA is not investigated yet. Objective aim the study to children real practice. Methods included proximal 5q administered abeparvovec. Diagnosis was verified by biallelic deletion 7th exon SMN1 gene. according decision neurologists consensus case absence antibodies...
Introduction. Predicting relapse in acute demyelinating episode (ADE) children is an urgent problem, since progressive diseases are associated with the risk of disability and cognitive impairment. Methods. Descriptive cohort study. The results long-term follow-up 75 after first demyelination presented. Based on clinical radiological parameters event, prognostic factors for were determined using logistic regression method. Results. When comparing instrumental signs we identified those that...