A5056218213- EEG and Brain-Computer Interfaces
- Neural dynamics and brain function
- Functional Brain Connectivity Studies
- Muscle activation and electromyography studies
- Motor Control and Adaptation
- Neurobiology and Insect Physiology Research
- Action Observation and Synchronization
Columbia University
2018-2024
Columbia University Irving Medical Center
2024
Stanford University
2014-2019
Center for Theoretical Physics
2018-2019
Society for Neuroscience
2018
Motor cortex (M1) has lateralized outputs, yet neurons can be active during movements of either arm. What is the nature and role activity across two hemispheres? We recorded muscles bilaterally while monkeys cycled with each Most were movement Responses strongly arm-dependent, raising possibilities. First, population-level signals might differ depending on arm used. Second, same present, but distributed differently neurons. The data supported this second hypothesis. Muscle was accurately...
Abstract Motor preparation typically precedes movement and is thought to determine properties of upcoming movements. However, has mostly been studied in point-to-point delayed reaching tasks. Here, we ask whether engaged during mid-reach modifications. Monkeys reach targets that occasionally jump locations prior onset, requiring a correction. In motor cortex dorsal premotor cortex, find the neural activity signals when predicts monkeys’ responses on trial-by-trial basis. We further identify...
Abstract In many neural populations, the computationally relevant signals are posited to be a set of ‘latent factors’ – shared across individual neurons. Understanding relationship between activity and behavior requires identification factors that reflect distinct computational roles. Methods for identifying such typically require supervision, which can suboptimal if one is unsure how (or whether) grouped into distinct, meaningful sets. Here, we introduce Sparse Component Analysis (SCA), an...
Abstract Primary motor cortex (M1) has lateralized outputs, yet M1 neurons can be active during movements of either arm. What is the nature and role activity in two hemispheres? When one arm moves, are contralateral ipsilateral cortices performing similar or different computations? both hemispheres active, how does brain avoid moving “wrong” arm? We recorded muscle neural bilaterally while male monkeys ( Macaca mulatta ) performed a cycling task with other Neurons were Yet response patterns...
In the fifty years since Evarts first recorded single neurons in motor cortex of behaving monkeys, great effort has been devoted to understanding their relation movement. Yet these exist within a vast network, nature which largely inaccessible. With advances recording technologies, algorithms, and computational power, ability study network-level phenomena is increasing exponentially. Recent experimental results suggest that dynamical properties networks are critical movement planning...
In the fifty years since Evarts first recorded single neurons in motor cortex of behaving monkeys, great effort has been devoted to understanding their relation movement. Yet these exist within a vast network, nature which largely inaccessible. With advances recording technologies, algorithms, and computational power, ability study network-level phenomena is increasing exponentially. Recent experimental results suggest that dynamical properties networks are critical movement planning...