Background: Oral mucositis is a debilitating side effect of cancer treatment for which there not much successful treatments at yet. We evaluated the effectiveness topical morphine compared with routine mouthwash in managing treatment-induced mucositis. Materials and Methods: Thirty head neck patients severe (World Health Organization Grade III or IV) were randomized into magic groups. Patients received sulfate 2% solution (contained magnesium aluminum hydroxide, viscous lidocaine,...

Background: Peripheral neuropathy is one of the most important limitations oxaliplatin base regimen, which standard for treatment colorectal cancer. Evidence has shown that Vitamin E may be protective in chemotherapy-induced peripheral neuropathy. The aim this study to evaluate effect administration on prevention oxaliplatin-induced patients with Methods: This was a prospective randomized, controlled clinical trial. Patients cancer and scheduled receive oxaliplatin-based regimens were...

Background: Diarrhea is a well-recognized side effect associated with pelvic radiation; however, there not any effective common treatment for radiation-induced diarrhea. A popular alternative probiotics, which have been used in several gastrointestinal disorders. Probiotics are live microbial food supplements. Furthermore, honey putative nutritional variety of health effects, including antibacterial, antioxidant, anti-inflammatory and prebiotic. The present study evaluated the effects...

Background: Radiotherapy is frequently used in treatment approaches of pelvic malignancies. Nevertheless, it has some known systemic effects on blood cells and the immune system that possibly results their susceptibility to infection. Probiotics are live microbial food ingredients provide a health advantage consumer. Honey prebiotic properties. The aim this clinical trial was investigate probable probiotic or probiotics plus honey cell counts serum IgA levels patients receiving radiotherapy....

Radiotherapy of head and neck cancers causes acute chronic xerostomia mucositis. Xerostomia increases risk radiation caries affects on oral comfort, fit prostheses, speech, swallowing, the growth caries-producing organisms. Salivary flow rate can be measured by asking patients some questions. There are different types commercial synthetic saliva such as BIOXTRA, but until now, no one effectively relieve xerostomia. We tried to design a clinical research BIOXTRA efficacy for treating...

Delivering radiotherapy to the postmastectomy chest wall can be achieved using matched electron fields. Surgical defects of change dose distribution electrons. In this study, improvement homogeneity simple, nonconformal techniques thermoplastic bolus application on a defect is evaluated. The proposed phantom design improves capability film dosimetry for obtaining profiles patient's anatomical condition. A modeled field patient with inward surgical was planned. High energy electrons were...

Background: Despite mammographic density being a strong indicator of breast cancer risk, it is unclear whether there association between and certain subtypes. This study aimed to investigate the relation radiologic category tumor characteristics. Methods: Patients with histologically proven who had undergone diagnostic mammography were reviewed retrospectively from 2016 2019. The American College Radiology BI-RADS categories recorded grouped into low (a b), high (c d). Patient...

For superficial lesions, the electrons may be used for radiation therapy. The high energy photons and are produced by a Linear accelerator (Linac). Many of electron fields need shielding normal or critical organs. shields usually lead slabs with few millimeter thicknesses which should placed near skin, less than 1 cm away from skin. In inspection patients setting in clinic physicist, it was noted that some cases technician places far skin way shadow field still matches shielded area. This is...

Background: Despite the high prevalence of acute radiation dermatitis (ARD) in breast treatment, data about its prevention is inconsistent. We conducted present research to investigate whether use topical corticosteroids with different potencies or moisturizing cream could prevent ARD. Method: In this double-blind randomized trial, 120 patients, who had undergone conserving surgery for cancer, were randomly assigned Mometasone 0.1% hydrocortisone 1% base from first day radiotherapy (RT)...

Introduction: One of the most important complications faced by cancer patients is chemotherapy-induced oral mucositis (CIOM). In addition, role orally used zinc sulfate in its prevention and treatment still a controversial issue results this regard have not been conclusive. Objectives: Evaluation effect supplement on CIOM breast treated with adriamycin cyclophosphamide was aim study. Patients Methods: The current double-blind randomized clinical trial conducted 87 cancer. Consumption two...

Background: The present study was aimed to evaluate the efficacy and safety of at least three cycles Bevacizumab in combination with chemotherapy regimens, FOLFIRI or FOLFOX treat liver metastatic colorectal cancer improved response rates these patients. Materials Methods: In this non-randomized clinical trial, 38 patients were enrolled followed for 12-weeks period chemotherapy. Fifteen under treated FOLOFX (Group I), 15 FOLOFIRI II), 4 + III), 34 IV). Response treatment assessed all as main...

83 Background: Breast carcinoma is the second cause of mortality between female cancers and metastasis main contributing factor to in patients with breast cancer. Optimal management for visceral metastatic cancer (MBC) remains unknown. In this study we aimed assess if adding pioglitazone chemotherapy regimen can improve response MBC. Methods: This double-blind randomized clinical trial enrolled women 18 years or older MBC either previously treated adjuvant therapy currently are undergoing...

Titanium (Ti) mesh plates are used as a bone replacement in brain tumor surgeries. In the case of radiotherapy, these might interfere with beam path. The purpose this study is to evaluate effect titanium on dose distribution electron fields. Simulations were performed using Monte Carlo BEAMnrc and DOSXYZnrc codes for 6 10 MeV beams. simulation, shape was simulated. simulated considered one which head neck surgery thickness 0.055 cm. First, by percentage depth obtained while present, values...

Many cellular damages either in normal or cancerous tissues are the outcome of molecular events affected by ionizing radiation. T-cells most important among immune system agents and used for biological radiation dose measurement recommended standard methods. The herbs with modulating properties may be useful to reduce risk subsequently diseases. as cells being targeted dosimetry This study proposes a flowcytometric-method based on fluorescein isothiocyanate- propidium iodide (PI)-labeled...

The cancer of oral cavity is related to lesions mucous membrane tongue and gum that can be treated with radiation therapy. A lateral photon field used treat this kind tumor, which has a side-effect on normal tissue in the opposite side cavity. In study dosimetric effect various shields evaluated. study, special phantom similar structure capability film dosimetry was designed constructed. shield slabs were made five materials: Lead, Plexiglas, Acrylic resin, Silicon Plaster. For irradiation,...

Abstract BACKGROUND: The purpose of this study is to investigate the relationship between mean heart dose received in left breast cancer radiation therapy and cardiac injury as measured by Pro-BNP Troponin laboratory levels ventricular systolic function, LVEF GLS echocardiography. METHOD: This research was carried out at Omid Hospital, Isfahan City, Iran, using before after intervention single-arm approach on a population patients diagnosed with who for 2021- 2022. Troponin, Pro-BNP, GLS,...