A5102826760- Elasticity and Material Modeling
- Aortic aneurysm repair treatments
- Cardiovascular Function and Risk Factors
- Cardiac Valve Diseases and Treatments
- Mechanical Engineering and Vibrations Research
Graz University of Technology
2022
King's College London
2021
Understanding the biomechanics of heart in health and disease plays an important role diagnosis treatment failure. The use computational biomechanical models for therapy assessment is paving way personalized treatment, relies on accurate constitutive equations mapping strain to stress. Current state-of-the art account nonlinear anisotropic stress-strain response cardiac muscle using hyperelasticity theory. While providing a solid foundation understanding tissue, most current laws neglect...
An insight into changes of soft biological tissue ultrastructures under loading conditions is essential to understand their response mechanical stimuli. Therefore, this study offers an approach investigate the arrangement collagen fibrils and proteoglycans (PGs), which are located within mechanically loaded aortic wall. The human samples were either fixed directly with glutaraldehyde in load-free state or subjected a planar biaxial extension test prior fixation. ultrastructure was recorded...