A5074352368- Semiconductor Lasers and Optical Devices
- Photonic and Optical Devices
- Optical Network Technologies
- Semiconductor Quantum Structures and Devices
- Advanced Fiber Laser Technologies
- Molecular Junctions and Nanostructures
- Optical Coatings and Gratings
- Glaucoma and retinal disorders
- Eosinophilic Disorders and Syndromes
- Advanced Photonic Communication Systems
- Urticaria and Related Conditions
- Advanced optical system design
- Eosinophilic Esophagitis
- Laser-Matter Interactions and Applications
- Quantum and electron transport phenomena
- Earthquake and Tsunami Effects
- Acute Myeloid Leukemia Research
- Photonic Crystals and Applications
- Iterative Learning Control Systems
- Chronic Myeloid Leukemia Treatments
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- Advanced Fiber Optic Sensors
- Seaweed-derived Bioactive Compounds
- Optical Wireless Communication Technologies
- Earthquake and Disaster Impact Studies
Oita University
2025
Nara Institute of Science and Technology
2007-2017
Jikei University School of Medicine
1992-2010
Japan Science and Technology Agency
2004-2008
Yamagata University Hospital
2006
Yamagata University
2002-2005
Tokyo Institute of Technology
1999-2005
Jikei University Kashiwa hospital
1992-2005
Kyoto University
1982-2003
Mitsubishi Electric (Japan)
1994
Despite the outstanding results generally obtained with imatinib mesylate (IM) in treatment of chronic myeloid leukemia (CML), some patients show a poor molecular response. To evaluate relationship between steady-state trough plasma IM concentration (IM-C(min)) and clinical response CML patients, we integrated data from six independent Japanese studies. Among 254 mean IM-C(min) was 1,010.5 ng/ml. Importantly, significantly higher who achieved major (MMR) than those did not (P = 0.002)....
We demonstrate a novel all-optical buffer memory using 1.55-μm polarization bistable vertical-cavity surface-emitting lasers (VCSELs). A one-bit data is stored as one of two orthogonal states VCSEL in this memory. The state transferred from the to another which optically connected cascade shift register. 4-bit optical constructed sets shift-register parallel. These results show technical feasibility multi-bit
Operation conditions of all-optical buffer memories based on polarization bistable vertical-cavity surface-emitting lasers (VCSELs) were investigated. The switching power dependence the frequency detuning input optical signal was measured for a 980-nm VCSEL. proper operating 10-Gb/s memory operation also and found to be negative side. Calculations two-mode rate-equation model successfully explained characteristics conditions. Maximum data rates strongly depended <i...
Polarization bistability of vertical-cavity surface-emitting lasers (VCSELs) is the situation in which two orthogonal linear polarization states can selectively and stably exist for a single operation condition (e.g., injected current temperature) provide switching between polarizations complex dynamics. This attractive photonic computing sense that complexity nonlinear node be enhanced. However, considered inherent to material properties cavity structure VCSELs, makes it difficult optimize...
The fastest known operation of all-optical flip-flop memory was experimentally demonstrated using a 980-nm polarization bistable vertical-cavity surface-emitting laser (VCSEL). Operating conditions the input signal power and frequency detuning to achieve fast optical were characterized experimentally. At optimum condition, 1-bit data signals arbitrarily sampled memorized from 2(6)-1 pseudorandom bit sequence return-to-zero at 20 Gb/s by AND gate functionalities obtained bistability. In...
We designed and fabricated a vertical-cavity surface-emitting laser (VCSEL) incorporating polarization-independent high-index-contrast subwavelength grating (HCG) mirror on silicon-on-insulator (SOI) for novel polarization-bistable device silicon substrate. The VCSEL consists of the HCG mirror, an active layer with InGaAsP quantum wells having optical gain around 1.55 μm, Al0.9Ga0.1As/Al0.16Ga0.84As DBR. used direct wafer bonding between AlGaAs DBR, benzocyclobutene (BCB) mirror....
<para xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink"> We discuss our demonstration of gigahertz switching lasing circular polarizations in a (110) GaAs-based vertical-cavity surface-emitting laser (VCSEL) obtained by optical spin injection. The (110)-VCSEL's significantly longer relaxation time (2.8 ns) than its carrier lifetime (0.42 enabled it to consecutively oscillate orthogonal with high degree polarization, when the delay between two pump...
A numerical model for the investigation of ultrafast gain properties in asymmetrical multiple quantum-well semiconductor optical amplifiers has been developed considering propagation ultrashort pulses with different wavelengths. The dynamics number carriers and carrier temperature are investigated each quantum well. results agree experimental pump probe measurements It is shown that recovery slower higher energy wells signals all
We demonstrate an optical header processing system using a 1.55-μm polarization bistable vertical-cavity surface-emitting laser (VCSEL) that operates as all-optical AND gate and holding element. Depending on the state of 1 bit in 4-bit header, VCSEL held one two-orthogonal states. The light output through polarizer switched switch. This enables payload to be sent destination determined by header. characteristics enable low-power consumption lower latency operation. also has potential process...
We measured the bit error rate (BER) of all-optical flip-flop operations using a 1.55-μm polarization bistable vertical-cavity surface-emitting laser (VCSEL). Polarization were obtained by injecting optical set and reset pulses with independently adjusted wavelengths toward two VCSEL lasing modes, whose polarizations are orthogonal to each other. Acquired waveforms showed clearly opened eyes, BERs less than 1 × 10 <sup xmlns:mml="http://www.w3.org/1998/Math/MathML"...
This paper considers the restoration of images degraded by a motion blur in presence noise. Based on two-dimensional separable autoregressive image model, one-dimensional horizontally causal vector state space model with multiple delays is derived. By discrete sine transform, decomposed into set nearly uncorrelated scalar subsystems, to which Kalman filter applied obtain an approximate recursive computationally efficient algorithm for images. The same technique also semicausal minimum...
We investigated all-optical shift register operations using 1.55-μm polarization bistable vertical-cavity surface-emitting lasers (VCSELs) formed in an array. The VCSEL array consisted of VCSELs that oscillated with single longitudinal and transverse modes at room temperature. lasing wavelengths were tuned by adjusting the driving currents each VCSEL. A exhibited flip-flop operation injection orthogonally polarized set-reset input pulses. By output light into another same through a polarizer...
We have demonstrated polarization bistability in 1.55 µm vertical-cavity surface-emitting lasers (VCSELs). InAlGaAs/InP VCSELs with square mesa structures oscillated the lowest-order transverse mode and one of two orthogonal linear states. Highly stable all-optical flip-flop operation was performed at telecommunication wavelength for first time by injecting orthogonally polarized light pulses.
We propose and evaluate an all-optical 2-bit header recognition packet switching method using two 1.55-µm polarization bistable vertical-cavity surface-emitting lasers (VCSELs) three optical switches. Polarization VCSELs acted as flip-flop devices by AND-gate operations of the set pulses, together with reset pulses. Optical packets including 40-Gb/s non-return-to-zero pseudo-random bit-sequence payloads were successfully sent to one four ports according state bits in headers a 4-bit 500-Mb/s...
Polarization switching between two orthogonal linear polarizations was experimentally demonstrated in newly designed 980-nm vertical-cavity surface-emitting lasers ( VCSELs ). A square-shaped mesa structure prepared a p-type distributed Bragg reflector mirror. Four p-side electrodes were placed contact with the four sides of square mesa. When same current injected into electrodes, VCSEL oscillated 0 or 90 polarizations. asymmetrically (the for on opposite square, but different neighboring...
The paper presents a new optical drive system incorporating acceleration disturbance suppression control in the focus actuator. uses observer based on modern theory to provide wide range of detection. As result, it has achieved significant improvement robustness from conventional systems.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Polarization bistable vertical-cavity surface-emitting lasers (VCSELs) with an oxidation confinement structure were fabricated for low power consumption operation. Threshold current of the VCSEL was reduced to 0.22 mA. The operated in a single longitudinal and transverse mode one two orthogonal linear polarization modes. All-optical flip-flop operation based on bistability achieved at record bias 1.15 mA, which is about tenth our previously developed without structure.
The T cell-lineage marker CD2 is sometimes expressed in acute promyelocytic leukemia (APL), and expression reported to correlate with some clinical characteristics. However, the significance of APL has not been fully elucidated. We evaluated treated by same treatment strategy a single institute, whether it had any special Among 29 APL, 6 were positive for CD2. Patients CD2+ tended have higher leukocyte count than CD2- (34.5 +/- 13.1/l vs. 6.8 2.1/l), morphological characteristics as...
We investigated detuning and repetition-frequency dependencies of minimum polarization switching optical power for all-optical flip-flop operation using 1.55-μm bistable VCSELs. demonstrated it up to 3.1-GHz frequency by 10-fJ pulses.
The gain dynamics of a multiple-quantum-well semiconductor optical amplifier with wide gain-bandwidth are measured by two-color pump-probe technique using pulses pulse duration on the order 100 fs. short generated selecting narrow spectral components from compressed supercontinuum filters.
We investigated all-optical flip-flop operations with AND-gate functionality by injecting data and set inputs different wavelengths to a 1.55-µm polarization bistable vertical-cavity surface-emitting laser. Control of the phase difference between two is not needed for stable operation, which differs from same wavelength case we have used thus far. Thus, this proposed method will simplify signal processing systems. The dependencies switching power timing jitter were measured 1-ns pulses. For...
Abstract We investigated the optical coupling between a polarization-independent high-index-contrast subwavelength grating (HCG) and two orthogonal in-plane waveguides. fabricated HCG with waveguides on silicon-on-insulator substrate demonstrated that waveguide strong output is switched by changing polarization of light injected into HCG. The coupled more strongly to in direction perpendicular incident than parallel direction. If this waveguide-coupled incorporated bistable vertical-cavity...
For suppressing the development of diabetes mellitus and onset complications, an insulin therapy has been used for normalizing change a blood glucose. In glucose control by linear method such as conventional ARMA, however, there exists problem that results in frequency hypoglycemia. prediction chaos theory, also lower accuracy on behalf impossibility long-time prediction. improvement looks like complicated time series, we propose system combining deterministic theory using equal interval,...