Augustin T. Twabela

ORCID: 0000-0003-0695-2734
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About
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Research Areas
  • Animal Disease Management and Epidemiology
  • Influenza Virus Research Studies
  • Viral Infections and Vectors
  • Respiratory viral infections research
  • Vector-Borne Animal Diseases
  • Rabies epidemiology and control
  • Virology and Viral Diseases
  • Viral Infections and Outbreaks Research
  • COVID-19 Clinical Research Studies
  • Bacillus and Francisella bacterial research
  • SARS-CoV-2 and COVID-19 Research
  • Viral gastroenteritis research and epidemiology
  • Mosquito-borne diseases and control
  • Yersinia bacterium, plague, ectoparasites research
  • SARS-CoV-2 detection and testing
  • Poxvirus research and outbreaks

Université Pédagogique Nationale
2024

Hokkaido University
2018-2021

Ministry of Public Health
2020

Food and Agriculture Organization of the United Nations
2018

Istituto Zooprofilattico Sperimentale delle Venezie
2018

Observatoire Volcanologique de Goma
2018

Abstract The role of Africa in the dynamics global spread a zoonotic and economically-important virus, such as highly pathogenic avian influenza (HPAI) H5Nx Gs/GD lineage, remains unexplored. Here we characterise spatiotemporal patterns virus diffusion during three HPAI intercontinental epidemic waves demonstrate that mainly acted an ecological sink viruses. A joint analysis host continuous spatial indicates poultry trade well wild bird migrations have contributed to spreading into Africa,...

10.1038/s41467-019-13287-y article EN cc-by Nature Communications 2019-11-22

Global dispersion of high pathogenicity avian influenza (HPAI), especially that caused by H5 clade 2.3.4.4, has threatened poultry industries and, potentially, human health. An HPAI virus, A/northern pintail/Hokkaido/M13/2020 (H5N8) (NP/Hok/20) belonging to 2.3.4.4b, was isolated from a fecal sample collected at lake in Hokkaido, Japan where migratory birds rested, October 2020. In the phylogenetic trees all eight gene segments, NP/Hok/20 fell into cluster European isolates 2020, but...

10.3390/v12121439 article EN cc-by Viruses 2020-12-14

BackgroundBas-Congo virus (BASV), an emerging tibrovirus, was associated with outbreak of acute haemorrhagic fever in Mangala, Democratic Republic the Congo, 2009. In 2012, neutralising antibodies to BASV were detected lone survivor and one his close contacts. However, subsequent serological molecular surveys unsuccessful as neither nor its RNA detected. this study, we determined seroprevalence infection Mangala 13 years after initial outbreak.MethodsWe conducted a population-based survey...

10.1016/s2666-5247(24)00021-1 article EN cc-by-nc-nd The Lancet Microbe 2024-03-28

In 2017, highly pathogenic avian influenza A(H5N8) virus was detected in poultry the Democratic Republic of Congo.Whole-genome phylogeny showed clustered with H5N8 clade 2.3.4.4B strains from birds central and southern Asia.Emergence this Africa represents a threat for animal health food security.T he detection (HPAI) infections has greatly increased past decades, particular as consequence spread HPAI subtype H5, descendent H5N1 A/goose/Guangdong/1/1996 (Gs/GD), which China 1996 (1).The...

10.3201/eid2407.172123 article EN cc-by Emerging infectious diseases 2018-06-04

Rabies is one of the major public health problems mostly affecting developing countries in Africa and Asia where 99.9% all rabies related human deaths are recorded each year. In Democratic Republic Congo, repeated outbreaks have been reported. Despite this, there little reliable epidemiological data about country for development effective control strategies.A retrospective study was carried out Kinshasa Province during a period five years (2009-2013) to describe proportion rabid animals...

10.1371/journal.pone.0150403 article EN cc-by PLoS ONE 2016-04-07

Newcastle disease (ND) is a highly transmissible and devastating that affects poultry wild birds worldwide. Comprehensive knowledge regarding the characteristics epidemiological factors of ND virus (NDV) critical for control prevention ND. Effective vaccinations can prevent spread NDV in populations. For decades, Democratic Republic Congo (DRC) has reported impacts on commercial traditional farming systems. The reports were preliminary clinical observations, few cases confirmed laboratory....

10.3390/v13020151 article EN cc-by Viruses 2021-01-20

Control measures in the case of high pathogenicity avian influenza (HPAI) outbreaks poultry include culling, surveillance, and biosecurity; wild birds captivity may also be culled, although some rare bird species should rescued for conservation. In this study, two anti-influenza drugs, baloxavir marboxil (BXM) peramivir (PR), used humans, were examined treating HPAI birds, using chickens as a model. Chickens infected with H5N6 virus treated immediately or 24 h from challenge 20 mg/kg BXM PR...

10.3390/v12121407 article EN cc-by Viruses 2020-12-08

Peste des petits ruminants (PPR) is an acute, contagious viral disease of small ruminants, goats and sheep. The Democratic Republic the Congo (DRC) was a PPR-free country until 2007, although in 2006, scare alerts were received from east southwest country, reporting repeated mortalities, specifically goats. In 2008, PPR outbreaks seen several villages west, leading to structured veterinary field operations. Blood, swabs pathological specimens consisting tissues lungs, spleens, lymph nodes,...

10.3390/v13122373 article EN cc-by Viruses 2021-11-26

Purpose: In 2006, 2014 and 2016 Africa was hit by three intercontinental epidemic waves of the highly pathogenic avian influenza virus (HPAIV) belonging to distinct genetic clades A/goose/Guangdong/1/1996 lineage, namely 2.2, 2.3.2.1c 2.3.4.4, which substantially affected local poultry industry. this study we compared global intra-African HPAIV H5 transmission patterns these shed light on spread within explore contributions different host populations introduction dissemination. Methods &...

10.1016/j.ijid.2018.11.041 article EN cc-by-nc-nd International Journal of Infectious Diseases 2019-01-30
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