- Influenza Virus Research Studies
- Animal Disease Management and Epidemiology
- Respiratory viral infections research
- Polyoxometalates: Synthesis and Applications
- Viral gastroenteritis research and epidemiology
- Viral Infections and Vectors
- Quantum Dots Synthesis And Properties
- Molecular Sensors and Ion Detection
- Animal Virus Infections Studies
- Chalcogenide Semiconductor Thin Films
- Peptidase Inhibition and Analysis
- Vector-Borne Animal Diseases
- Asthma and respiratory diseases
- Fluoride Effects and Removal
- RNA and protein synthesis mechanisms
- Vanadium and Halogenation Chemistry
- Ocular Surface and Contact Lens
- Spectroscopy and Quantum Chemical Studies
- Monoclonal and Polyclonal Antibodies Research
- Polymer Surface Interaction Studies
- Protist diversity and phylogeny
- Semiconductor materials and interfaces
- Glaucoma and retinal disorders
- Corneal surgery and disorders
- Sarcoidosis and Beryllium Toxicity Research
Hokkaido University
2013-2025
Hokkaido University of Science
2024
National Institute of Technology, Kisarazu College
2023
Shizuoka Institute of Science and Technology
2022
Tokyo University of Agriculture
2020
Yamagata University
2017
Akita Prefectural University
2013
High pathogenicity avian influenza (HPAI) has impacted poultry and wild birds globally. The number of H5 HPAI virus (HPAIV) infection cases in Hokkaido (Northern Japan) was high the last two seasons, contributing to spillover resident poultry. Therefore, HPAIVs mammals winter 2022–2023 2023–2024 were monitored viruses phylogenetically, antigenically, pathogenetically characterized. Thirty HPAIV isolates subtyped pathotyped by sequencing hemagglutinin (HA) gene viruses. Phylogenetic analysis...
Global dispersion of high pathogenicity avian influenza (HPAI), especially that caused by H5 clade 2.3.4.4, has threatened poultry industries and, potentially, human health. An HPAI virus, A/northern pintail/Hokkaido/M13/2020 (H5N8) (NP/Hok/20) belonging to 2.3.4.4b, was isolated from a fecal sample collected at lake in Hokkaido, Japan where migratory birds rested, October 2020. In the phylogenetic trees all eight gene segments, NP/Hok/20 fell into cluster European isolates 2020, but...
The Hofmeister series has long been of both scientific and technological importance because it allows systematic predictions the interaction between ions molecules to be made. In this work, three different polyoxometalate (POM) anions lipid monolayers were used investigate interplay electrostatic hydrophobic interactions. We Keggin-type POMs with charges ([PW12O40]3–, [SiW12O40]4–, [H2W12O40]6–) eliminate any effects morphology focus on charge hydrophobicity POM anions. adsorb onto cationic...
ABSTRACT Influenza A viruses with fewer amino acids in the neuraminidase (NA) stalk domain are primarily isolated from chickens rather than wild ducks, indicating that a shortened NA is considered an adaptation marker of avian influenza (AIVs) to chickens. Experimental passages H7N7 nonpathogenic AIV (rgVac2-P0) resulted highly pathogenic variant (Vac2-P3L4) 34-amino-acid deletion stalk, encompassing five potential N -glycosylation sites. To investigate how acid truncation and...
Starch, unlike hydrosoluble glycogen particles, aggregates into insoluble, semicrystalline granules. In photosynthetic eukaryotes, the transition to starch accumulation occurred after plastid endosymbiosis from a preexisting cytosolic host metabolism network. This involved recruitment of debranching enzyme chlamydial pathogen origin. The latter is thought be responsible for removing misplaced branches that would otherwise yield water-soluble polysaccharide. We now report implication in...
Abstract ZnS and CdZnS (a mixed crystal phase of CdS) were formed using the open-air CVD method. Cadmium diethyldithiocarbamate (C 10 H 20 CdN 2 S 4 ) zinc ZnN used as source materials for CdS ZnS, respectively. By changing ratio materials, it was found that bandgap lattice constant film continuously without a miscibility gap. Furthermore, obtained films less than reported (3.68 eV) due to incorporation oxygen. X-ray diffraction analysis revealed increase Zn in generated crystalline...
We report the structure-dependent effects of polyoxometalate (POM), a bioactive cluster material, on liposome collapse activity. Structure and lacunary state POM were found to have critical role govern efficiency kinetics model cell membranes. Keggin-type demonstrated fast activity, but with different efficiencies dependent state. Furthermore, an increase in size changed its kinetic properties, from delayed This transition is discussed terms energy barrier during process.
Abstract Polybasic amino acid residues at the hemagglutinin (HA) cleavage site are insufficient to induce highly pathogenic phenotype of avian influenza viruses in chickens. In our previous study, an H7N7 virus named Vac2sub-P0, which is non-pathogenic despite carrying polybasic acids HA site, was passaged chick air sacs and a with high intravenous pathogenicity, namely, Vac2sub-P3, obtained. Intranasal infection Vac2sub-P3 only partially lethal chickens; therefore, this further chicken...
Optimal screening interval for intraocular pressure measurement Asian glaucoma patients
The primary objective of this preliminary intervention study was to clarify the effect continuous intake onion outer skin powder granules (onion peel made into with edible excipients) on human intestinal microflora by molecular microbiological methods.Furthermore, second isolate bacterial strains that show characteristic growth successive cultivation in fecal medium supplemented powder, and obtain basic data such as their role quercetin metabolism.Although statistically significant results...