Retinopathy of prematurity (ROP) is a result increased pathological neoangiogenesis the retina in preterm infants. Cells responsible for pathogenesis ROP are unclear, but some evidence indicates that bone marrow derived cells involved this disorder. Endothelial progenitor (EPCs), play role angiogenesis response to tissue ischemia or endothelial damage. In study, number cEPCs infants with was determined identify whether circulation mobilization EPCs associated ROP. We evaluated 99...

Diabetes mellitus is the most common chronic endocrine disease worldwide. Intensive glycemic control plays an important role in decreasing morbidity and mortality rate of disease. Preclinical studies have shown that biotin has essential regulating blood glucose serum lipid metabolism. This study aims to evaluate effect on plasma lipids concentrations type 1diabetic patients.This randomized double-blind placebo-controlled clinical trial was conducted 70 1 diabetic patients with age range 5-25...

Introduction: Patent ductus arteriosus (PDA) is one of the most common cardiac problems in preterm neonates which could lead to morbidities, such as chronic lung disease, intraventricular hemorrhage and retinopathy. The aim this study was evaluate effect oral acetaminophen on closure PDA neonates.
 Methods: Sixty-nine with significant (confirmed through echocardiography) were recruited study. Ibuprofen indomethacin contraindicated these These newborns randomly divided into two groups...

Many infants who develop bronchopulmonary dysplasia (BPD) are born with serious respiratory distress syndrome (RDS), which is associated impaired vascular and alveolar growth. RDS a breathing disorder that mostly affects preterm occurs in whose lungs have not yet been fully developed. The use of surfactant treatment does necessarily prevent BPD. Endothelial progenitor cells (EPCs) may contribute to lung angiogenesis for the prevention aim this study was evaluate therapeutic efficacy...

Background Neonatal mortality rate is one of the main indicators health care systems in each country. The first step improving level these to identify causes neonatal dead and its related factors. In this study, factors intensive unit at Imam Reza hospital were investigated. Materials Methods A descriptive cross sectional study was carried out from 2014 2016, on all neonates who died Hospital Kermanshah city, Iran. Information about infant, mother infant collected records families physician...

Background: This study aimed to evaluate the safety and efficacy of inhaled salbutamol for treatment Transient Tachypnea Newborn (TTN). Methods: Totally, 80 neonates with TTN were randomly assigned into two groups placebo. The placebo received one dose nebulized (dose 0.15 ml/kg in 2 ml normal saline) only 0.9% saline without salbutamol, respectively. Before starting and30, 60 min, 4 h after nebulization, respiratory heart rates, oxygen saturation, a fraction inspired oxygen, distress score,...

Background: Neonatal jaundice is a common condition in approximately 60% of term newborns during the first week after birth. Therefore, it necessary to detect methods for prevention this problem.This study was conducted evaluate impact massage therapy on transcutaneous bilirubin level healthy newborns. Methods: The present on102 were randomly assigned group and control group. received daily five days from postnatal day while only routine neonatal care (without massage). In both groups,...

Background: Despite the reduction of infant mortality in world, complication preterm birth is a major cause mortality. The present study aimed to evaluate effect abdominal massage and non-nutritive sucking on physiological parameters infants neonatal intensive care units Emam Reza Hospital Kermanshah, Iran. Materials Methods: In this randomized controlled clinical trial, 42 who had inclusion criteria, were selected randomly assigned three groups control (14 for each group). Abdominal first...

Background Jaundice is one of the most common problems in neonatal period. Although efficacy exchange transfusion treatment jaundice knownand quickly reduces blood bilirubin levels, but severe hyperbilirubinemia associated with significant morbidity and mortality. We conducted this study to investigate risk factorsof neonates undergoing Imam Reza Hospital Kermanshah, Iran. Materials Methods In retrospective study, records newborns who were hospital Kermanshah from 2012 2016 studied....

Background: Jaundice is observed during the 1st week of life in approximately 60% term infants. This study was aimed to evaluate effect oral zinc sulfate prevention jaundice healthy newborns. Methods: In this clinical trial study, 124 infants with postnatal age less than 24 hours, that were born Imam Reza Hospital (AS) Kermanshah, enrolled and equally divided into two groups, experimental control (n=62). The group only received routine neonatal care without any intervention. treatment group,...

Background Non-nutritive sucking is part of the initial development process in preterm infants that may speed up transition from tube to oral feeding. The aim this study was evaluate effect non-nutritive on mother's finger feeding tolerance and attainment independent infants. Materials Methods This single blind clinical trial conducted 40 admitted NICU Imam Reza Hospital, Kermanshah 2017. In intervention group, performed three times a day for 10 days during first minutes gavage. Then,...

Purpose: The aim of this study was to compare the effect supine and prone positions on physiological parameters preterm infants under nasal continuous positive airway pressure (N-CPAP). Materials Methods: This cross-over clinical trial conducted 62 hospitalized N-CPAP in neonatal intensive care unit Imam Reza Hospital Kermanshah, Iran. Neonates were placed position at first for 180 minutes then their changed into another minutes. During period, heart rate (HR), respiratory (RR) arterial...

Background: The present study aimed to evaluate the effect of synbiotics on intestinal colonization rate Candida albicans in low birth weight neonates (i.e., under 2,500 g), which is one most important events for necrotizing enterocolitis (NEC).Methods: During year, 106 preterm with a less than g, admitted Neonatal Intensive Care Unit (NICU) Imam Reza Hospital, affiliated Kermanshah University Medical Sciences, Kermanshah, Iran, were randomly selected and investigated two groups case...

Background: Necrotizing enterocolitis (NEC) is a multifactorial disease primarily affecting infants with very low birth weight (VLBW). Research has shown that the pathogenesis of NEC associated abnormal bacterial colonization. Synbiotics, dietary supplements containing probiotics (beneficial bacteria) and prebiotics (non-digestible food), can alter gut microbiome. Methods: A double-blind, randomized controlled trial was conducted to assess efficacy PediLact ® , an oral drop multi-strain...