A5103000219- Mechanical Circulatory Support Devices
- Cardiac Structural Anomalies and Repair
- Cardiac Arrest and Resuscitation
- Transplantation: Methods and Outcomes
- Congenital Heart Disease Studies
- Cardiac and Coronary Surgery Techniques
- Fuel Cells and Related Materials
- Organ Transplantation Techniques and Outcomes
- Heart Failure Treatment and Management
- Respiratory Support and Mechanisms
- Cardiac pacing and defibrillation studies
- Cardiac Valve Diseases and Treatments
- COVID-19 Clinical Research Studies
- Financial Reporting and Valuation Research
- Cell Adhesion Molecules Research
- Renal Transplantation Outcomes and Treatments
- Viral Infections and Immunology Research
- Infective Endocarditis Diagnosis and Management
- Kawasaki Disease and Coronary Complications
- COVID-19 and healthcare impacts
- Cardiovascular Function and Risk Factors
- Chemical and Physical Studies
- Tracheal and airway disorders
- Organ and Tissue Transplantation Research
- Acute Kidney Injury Research
Penn State Milton S. Hershey Medical Center
2014-2024
Pennsylvania State University
2011-2024
Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico
2023
Italfarmaco (Italy)
2023
University of Massachusetts Amherst
2023
Kermanshah University of Medical Sciences
2019
Imam Reza Hospital
2019
NIHR Bristol Cardiovascular Biomedical Research Unit
2018
University of Bristol
2018
John Radcliffe Hospital
2018
Development of aortic insufficiency (AI) in patients supported with continuous flow left ventricular assist devices (LVAD) can adversely affect pump performance. In this study, we examined the incidence new AI after LVAD implant at our institution. Pre- and postoperative echocardiograms 66 who received HeartMate II or Heartware institution since June 2008 were reviewed for presence AI. Median support duration was 221 days. New developed 6 (9.5%) a median time 374.5 days support. There no...
In several case reports and series, extracorporeal membrane oxygenation during chest compression (CPR) has been shown to be a reasonable tool improve outcome of patients under resuscitation. Although recommendations for cardiopulmonary resuscitation (ECPR) include younger with shockable rhythm short previous CPR-time, it remains unclear if nonhighly selected have similar outcome. Aim this study was determine in our patient population treated ECPR investigate possible predictors survival. We...
Objectives: Acute myocardial infarction is the most common cause of cardiogenic shock. Although number patients with acute complicated by shock who were treated venoarterial extracorporeal membrane oxygenation increased during last decade, detailed data on survival are lacking. We sought to analyze covariates that independently associated in this patient population and externally validate newly developed prEdictioN Cardiogenic OUtcome foR salvaGed Extracorporeal (ENCOURAGE) score. Design:...
Background: In patients supported with extracorporeal membrane oxygenation, and who develop heparin-induced thrombocytopenia, there is no clear evidence to support changing a non-heparin-coated oxygenation circuit. Our goal was evaluate clinical outcomes of were continued on heparin-bonded circuits despite diagnosed thrombocytopenia. Methods: We completed single-center retrospective study all underwent from July 2008 2017 tested thrombocytopenia positive while support. After diagnosis mean...
The optimal timing of left ventricular assist device (LVAD) implantation in the management advanced heart failure remains controversial. We hypothesize that patients with cardiogenic shock, severity end-organ dysfunction as determined by sequential organ assessment (SOFA) score is a determinant outcomes after LVAD implantation. preoperative SOFA and short- long-term 97 consecutive who received HeartMate II or HeartWare at our institution since January 2007. Kaplan-Meier analysis was used to...
Objectives: Cardiogenic shock [CS] is associated with a high-mortality. Suitable patients maybe successfully bridged using newer intravascular micro-axial left-ventricular assist devices [M-LVAD] for recovery or determination of definitive therapy. Methods: Between January-2020 and July-2024, 107 underwent placement M-LVAD CS. The cohort was divided into 4 groups based on their destination; group-1: 34 [32%] receiving transplant; group-2: 25 [23%] durable LVAD; group-3: 42 [39%] bridging...
Background: Renal failure is a common occurrence in patients with refractory cardiogenic shock including those supported veno-arterial extracorporeal membrane oxygenation. Prevalence and outcome of acute chronic kidney oxygenation have not been well documented. In this study, we investigated the as predictors for survival. Methods: This single center retrospective clinical study. We included adult who were by between 2008 2015. The primary endpoint study was injury (KDIGO Stage 3) during...
Summary Transplant coronary artery disease is the pre-eminent cause of late cardiac allograft failure. It primarily characterized by a concentric intimal hyperplasia, which we designate transplant hyperplasia (TIH). Although pathogenesis TIH predominately immune driven, specific role alloantibodies in process remains undefined. In this study investigated contribution to development murine model. Orthotopic, carotid transplantation was performed between B10A(2R) (H-2h2) donor mice and B-cell...