- Mechanical Circulatory Support Devices
- Parkinson's Disease Mechanisms and Treatments
- Neuroscience and Neuropharmacology Research
- Cardiac Arrest and Resuscitation
- Cardiac Structural Anomalies and Repair
- Coronary Interventions and Diagnostics
- Respiratory Support and Mechanisms
- Neurological disorders and treatments
- Neurotransmitter Receptor Influence on Behavior
- Cardiac pacing and defibrillation studies
- Vascular Procedures and Complications
- Organ Transplantation Techniques and Outcomes
- ECG Monitoring and Analysis
- Anesthesia and Pain Management
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Central Venous Catheters and Hemodialysis
- Airway Management and Intubation Techniques
- Diabetes Management and Research
- Shoulder Injury and Treatment
- Enzyme Production and Characterization
- Cerebrovascular and Carotid Artery Diseases
- Genetic Neurodegenerative Diseases
- Cardiac electrophysiology and arrhythmias
- Liver Disease and Transplantation
- Venous Thromboembolism Diagnosis and Management
Penn State Milton S. Hershey Medical Center
2016-2025
Mahatma Gandhi Memorial Medical College
2021
Pennsylvania State University
2016
University of California, San Francisco
2014
Kaiser Permanente San Francisco Medical Center
2013
The University of Texas Southwestern Medical Center
2007-2012
Southwestern Medical Center
2007-2012
Ochsner Health System
2011
Rutgers New Jersey Medical School
2011
Ochsner Medical Center
2011
Abstract The dopamine agonist, bromocriptine, produced either inhibition or stimulation of motor behaviour in rats depending upon the dose and time after administration. Stimulation activity occurred only with high doses a 1–2 h delay. Both were associated decreased turnover brain. Release noradrenaline brain plus adrenaline adrenal varied activity. It is suggested that low bromocriptine inhibit by activating an inhibitory presynaptic receptor, resulting reduced synthesis release dopamine,...
Surgery after drug-eluting stent (DES) implantation may be associated with increased risk for perioperative thrombosis (ST).We evaluated the outcomes of 67 patients who underwent non-cardiac (n=51) or cardiac (n=16) surgery DES at our institution between 2008 and 2010 preoperative "bridging" a glycoprotein IIb/IIIa inhibitor. occurred mean time 13.9 ± 1.7 8.7 2 months post stenting (NCS) surgery, respectively. Glycoprotein inhibitors were administered preoperatively 7.1 0.4 7.8 0.7 days,...
Background Short QT syndrome (QTc ≤ 300 ms) is a novel hereditary channelopathy linked to syncope, paroxysmal atrial fibrillation, and sudden cardiac death. However, its epidemiological features remain unsettled. Objectives (1) To assess the prevalence of short in large population‐based sample; (2) evaluate demographic clinical correlates and; (3) determine prognosis. Methods A database 6.4 million electrocardiograms (ECGs) obtained between 1995 2008 among 1.7 persons was used. An internal,...
Research Article| April 01 1952 A technique for the identification and separation of enzymes by paper chromatography K. V. Giri; Giri 1Department Biochemistry, Indian Institute Science, Bangalore Search other works this author on: This Site PubMed Google Scholar A. L. N. Prasad; Prasad S. Gowri Devi; Devi J. Sri Ram Biochem J (1952) 51 (1): 123–128. https://doi.org/10.1042/bj0510123 Views Icon Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Facebook Twitter...
To test possible biochemical mechanisms by which L-tryptophan may reverse mental side effects of levodopa therapy in parkinsonism we administered levodopa, 250 mg per kilogram intraperitoneally, alone and with L-tryptophan, 500 to rats pretreated the peripheral dopa decarboxylase inhibitor, carbidopa (25 kilogram). Rats were decapitated 0.5, 1, 2 hours following amino acid injection brain levels acids, amines, metabolites determined. As expected, reduced tryptophan serotonin increased...
Abstract Veno‐arterial extracorporeal membrane oxygenation (VA‐ECMO) provides mechanical circulatory support for patients with advanced cardiogenic shock, facilitating myocardial recovery and limiting multi‐organ failure. In severely limited left ventricular ejection, peripheral VA‐ECMO can further increase atrial pressures (LAP). Failure to decompress the heart under these circumstances result in pulmonary edema upper body hypoxemia, that is, cerebral ischemia. Atrial septostomy decrease...
Aim: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), or COVID-19, infection resulting in distress (ARDS) requiring veno-venous veno-arterial extracorporeal membrane oxygenation (VV VA-ECMO) support is a life-threatening disease process that requires prolonged intubation and has high risk of mortality. Methods: In this retrospective, observational, single-center cohort study, we attempt to better understand the role extubation course treatment by dichotomizing groups into those...
The purpose of this study was to ascertain, in the context an integrated health care delivery system, association between a comprehensive list drugs known have potential QT liability and prolongation or shortening.By using self-controlled crossover with 59 467 subjects, we ascertained intra-individual change log-linear regression-corrected (QTcreg ) during period 1995 mid-2008 for 90 while adjusting age, gender, race/ethnicity, comorbid conditions, number electrocardiograms (ECGs), time...
The inability to achieve 85% of the maximum predicted heart rate (MPHR) on dobutamine stress echocardiography (DSE) is defined as chronotropic incompetence and a predictor major cardiac events after orthotopic liver transplantation (OLT). majority patients with end-stage disease (ESLD) receive beta-blockers for prevention variceal bleeding. In these patients, it impossible determine whether secondary cirrhosis-related autonomic dysfunction or merely beta-blocker effect. We evaluated...
Arterial access dissections may complicate cardiac catheterization and can often be treated percutaneously. The goal of this study was to examine the incidence, consequences, treatment arterial at a tertiary referral hospital with an active training program.Patients experiencing dissection during coronary angiography or intervention our institution between October 1, 2004, January 31, 2007, were identified their records retrospectively reviewed.Thirteen 3,062 consecutive patients (0.42%) had...
Atypical antipsychotics (AAP) have been associated with reduced duration of delirium in the intensive care setting. However, long-term use these drugs is significant adverse events, including increased all-cause mortality elderly. Inappropriate continuation AAPs after discharge from unit (ICU) worrisome and needs to be addressed.The aim this work was assess prevalence hospital evaluate risk factors.This a single-center retrospective chart analysis setting adult ICUs at tertiary academic...
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTGrowth and Biochemical Characteristics of Micrococcus lysodeikticus, Sensitive or Resistant to Lysozyme*A. L. N. Prasad Gerald LitwackCite this: Biochemistry 1965, 4, 3, 496–501Publication Date (Print):March 1, 1965Publication History Published online1 May 2002Published inissue 1 March 1965https://pubs.acs.org/doi/10.1021/bi00879a018https://doi.org/10.1021/bi00879a018research-articleACS PublicationsRequest reuse permissionsArticle...