A5078621310- Colorectal Cancer Surgical Treatments
- Colorectal Cancer Screening and Detection
- Colorectal and Anal Carcinomas
- Inflammatory Bowel Disease
- Cardiac, Anesthesia and Surgical Outcomes
- Gastric Cancer Management and Outcomes
- Clinical practice guidelines implementation
- Microscopic Colitis
- Pancreatic and Hepatic Oncology Research
- Reproductive Biology and Fertility
- Health Systems, Economic Evaluations, Quality of Life
- Colorectal Cancer Treatments and Studies
- Patient-Provider Communication in Healthcare
- Diverticular Disease and Complications
- Radiomics and Machine Learning in Medical Imaging
- Ovarian function and disorders
- Reproductive Health and Technologies
- Anorectal Disease Treatments and Outcomes
- Intraperitoneal and Appendiceal Malignancies
- Enhanced Recovery After Surgery
- Cancer survivorship and care
- Economic and Financial Impacts of Cancer
- Genetic factors in colorectal cancer
- Appendicitis Diagnosis and Management
- Pelvic floor disorders treatments
Mount Sinai Hospital
2016-2025
University of Toronto
2016-2025
Sinai Health System
2001-2024
University College Cork
2024
Princess Margaret Cancer Centre
2011-2023
University Health Network
2009-2023
Health Sciences Centre
2023
McGill University Health Centre
2022-2023
Providence Health Care
2023
Juravinski Hospital
2023
Toronto was the site of North America's largest outbreak severe acute respiratory syndrome (SARS). An understanding patterns transmission and effects on public health in relation to control measures that were taken will help officials prepare for any future outbreaks.We analyzed SARS case, quarantine, hotline records measures. The two phases compared.Toronto Public Health investigated 2132 potential cases SARS, identified 23,103 contacts patients as requiring logged 316,615 calls its...
Sleep loss in attending physicians has an unclear effect on patient outcomes. In this study, we examined the of medical care provided by after midnight outcomes their scheduled elective procedures performed during day.We conducted a population-based, retrospective, matched-cohort study Ontario, Canada. Patients undergoing 1 12 daytime physician who had treated patients from to 7 a.m. were matched 1:1 ratio same procedure day when not midnight. Outcomes included death, readmission,...
<h3>Importance</h3> Chemoradiotherapy (CRT), followed by surgery, is the recommended approach for stage II and III rectal cancer. While CRT decreases risk of local recurrence, it does not improve survival leads to poorer functional outcomes than surgery alone. Therefore, new approaches better select patients are important. <h3>Objective</h3> To conduct a phase 2 study evaluate safety feasibility using magnetic resonance imaging (MRI) criteria with "good prognosis" tumors primary surgery....
Fistulas occur in about 25% of patients with Crohn’s disease (CD) and can be difficult to treat. The aim this consensus was provide guidance for the management perianal fistulizing CD. A systematic literature search identified studies on quality evidence strength recommendations were rated according Grading Recommendation Assessment, Development Evaluation (GRADE) approach. Statements developed through an iterative online platform using a modified Delphi process, then finalized, voted by...
The purpose of this article is to evaluate the diagnostic performance MRI for detection extramural venous invasion (EMVI) compared with histopathologic analysis using elastin stain.Forty-nine patients rectal cancer who had undergone surgical resection preoperative were identified. Thirty-seven received chemoradiation therapy (CRT). Sixty-nine studies independently reviewed by two blinded radiologists EMVI a score 0-4. Comparison was made results obtained pathologists reviewing...
Importance Over the last 2 decades, increasing use of multimodal strategies has led to significant improvements in oncologic outcomes for patients with rectal cancer. However, uptake these varies among centers, suggesting that best evidence is not always implemented into practice. Objectives To identify gaps care and initiate knowledge translation interventions close existing gaps. Design, Setting, Participants This 3-year multifaceted, prospective quality improvement study was conducted at...
Objective To determine the incidence of small bowel obstruction (SBO), to identify risk factors for its development, and most common sites adhesions causing SBO in patients undergoing ileal pouch–anal anastomosis (IPAA). Methods All IPAA at Mount Sinai Hospital were included. Data obtained from institution’s database, patient charts, a mailed questionnaire. was based on clinical, radiologic, surgical findings. Early defined as hospital stay greater than 10 or 14 days because delayed...
PURPOSE: This study was designed to evaluate the pregnancies, method of delivery, and functional results females with chronic ulcerative colitis who have an ileal pouch-anal anastomosis. METHODS: A mailed questionnaire sent all anastomosis for colitis. Information on pregnancy, outcome collected. Those had a successful pregnancy delivery were contacted by telephone clarify determine pouch results. Other clinical information obtained from Mount Sinai Hospital Inflammatory Bowel Disease...
Abstract Background In Ontario, FOLFIRINOX (FFX) and gemcitabine + nab‐paclitaxel (GnP) have been publicly funded for first‐line unresectable locally advanced pancreatic cancer (uLAPC) or metastatic (mPC) since April 2015. We examined the real‐world effectiveness safety of FFX vs GnP cancer, in uLAPC mPC. Methods Patients receiving from 2015 to March 2017 were identified New Drug Funding Program database. Baseline characteristics outcomes obtained through Ontario Cancer Registry other...
Infertility can be a devastating adverse effect of cancer treatment for young women. Fertility preservation may an important and influential factor in decisions. Despite American Society Clinical Oncology guidelines recommending discussion around potential infertility with patients, nearly 50% women remain uninformed.
BACKGROUND: Although the body of evidence supporting nonoperative management for rectal cancer has been accumulating, there little systematic investigation to explore how physicians and patients value tradeoffs between oncologic functional outcomes after abdominal perineal resection management. OBJECTIVE: The purpose this study was elicit patient physician preferences relative in setting low cancer. DESIGN: We conducted a standardized interviews cross-sectional survey physicians. SETTINGS:...
Abstract Background Increased length of stay after surgery is associated with increased healthcare utilization and adverse patient outcomes. While enhanced recovery (ERAS) protocols have been shown to reduce colorectal in trial settings, their effectiveness real-world settings more uncertain. The aim this study was assess the impact ERAS protocol implementation on surgery, using data. Methods In 2012, were introduced at 15 Ontario hospitals as part iERAS study. A cohort patients undergoing...
BACKGROUND: Although multidisciplinary cancer conferences have been reported to lead improved patient outcomes, few studies results of these for rectal cancer. OBJECTIVE: The purpose this work was assess the quality conferences, effect conference on initial treatment plan, compliance with recommendations, and clinical outcomes DESIGN: This a prospective, longitudinal study. SETTINGS: study conducted at tertiary care academic hospital. PATIENTS: Patients primary were included in INTERVENTION:...
Abstract Background & Aims Crohn’s disease (CD) is a lifelong illness with substantial morbidity, although new therapies and treatment paradigms have been developed. We provide guidance for of ambulatory patients mild to severe active luminal CD. Methods performed systematic review identify published studies the management The quality evidence strength recommendations were rated according Grading Recommendation Assessment, Development Evaluation (GRADE) approach. Statements developed...
Purpose Patient decision aids are interventions designed to help patients make deliberative choices about their treatment options and have been shown significantly improve patient outcomes. Although considered optimal, not widely used in clinical practice for cancer treatment. The objectives of this study determine physicians' awareness use aids, perceptions the major barriers physician characteristics predictive practice. Methods A population-based survey was mailed general surgeons,...
BACKGROUND: Colorectal cancer physician champions across the province of Ontario, Canada, reported significant concern about appropriate selection patients for preoperative chemoradiotherapy because perceived variation in completeness and consistency MRI reports. OBJECTIVE: The purpose this work was to develop, pilot test, implement a synoptic report staging rectal cancer. DESIGN: This an integrated knowledge translation project. SETTINGS: study conducted Canada. PATIENTS: Surgeons,...
Educational demands coupled with restricted hours reduce residents' availability to provide care at academic hospitals. Physician assistants (PAs) may address this issue. This study assessed the effect of PAs on patient discharges, resident workload, and perceptions a surgical team.Two were employed teams caring for complex patients. Measures included time discharge order entry, residents spent electronic medical record (EMR), opinions PA effectiveness.The had 0.5% late 16% early rate....
Objective: The purpose of the present review was to provide evidence-based guidance about provision cytoreductive surgery (crs) with hyperthermic intraperitoneal chemotherapy (hipec) in treatment peritoneal cancers. Methods: guideline developed by Program Evidence-Based Care together Surgical Oncology at Ontario Health (Cancer Ontario) through a systematic relevant literature, patient- and caregiver-specific consultation, internal external reviews. Results: Recommendation 1a: For patients...